MOLECULAR RECOGNITION OF SULFAQUINOXALINE AND SULFAPYRIDINE WITH MOLECULARLY IMPRINTED POLYMER

The selective separation of sulfapyridine (SPD) from sulfaquinoxaline (SQX) is investigated by applying high performance liquid chromatography (HPLC) with molecularly imprinted polymer (MIP) as the stationary phase. Herein we report the synthesis of a molecularly imprinting polymer, SPD-MIP, by free...

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Autores principales:	CHENG,T. C, HUANG,Y. T, CHANG,C. Y, YAO,K. S, HWANG,C.C
Lenguaje:	English
Publicado:	Sociedad Chilena de Química 2009
Materias:	selective separation sulfapyridine (SPD) sulfaquinoxaline (SQX) high performance liquid chromatography (HPLC) molecularly imprinted polymer (MIP)
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072009000300019
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spelling	oai:scielo:S0717-970720090003000192010-03-17MOLECULAR RECOGNITION OF SULFAQUINOXALINE AND SULFAPYRIDINE WITH MOLECULARLY IMPRINTED POLYMERCHENG,T. CHUANG,Y. TCHANG,C. YYAO,K. SHWANG,C.C selective separation sulfapyridine (SPD) sulfaquinoxaline (SQX) high performance liquid chromatography (HPLC) molecularly imprinted polymer (MIP) The selective separation of sulfapyridine (SPD) from sulfaquinoxaline (SQX) is investigated by applying high performance liquid chromatography (HPLC) with molecularly imprinted polymer (MIP) as the stationary phase. Herein we report the synthesis of a molecularly imprinting polymer, SPD-MIP, by free radical polymerization process. Because of this powerful method synthetic polymers with specific binding sites to template molecule are provided. In addition, the separation performances were represented by using buffer/acetonitrile (3/2, v/v) as mobile phase under 272 nm UV detection. In order to compare the chromatographic data from the stationary phase, capacity factor (k') and separation factors (á) were given. The value of 2.71 (á) revealed that the MIP was able to recognize structurally subtle differences from the template molecule. Our results are discussed with regard to the amount of template, the composition of the chromatographic mobile phase and adsorption capacity.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.54 n.3 20092009-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072009000300019en10.4067/S0717-97072009000300019
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	selective separation sulfapyridine (SPD) sulfaquinoxaline (SQX) high performance liquid chromatography (HPLC) molecularly imprinted polymer (MIP)
spellingShingle	selective separation sulfapyridine (SPD) sulfaquinoxaline (SQX) high performance liquid chromatography (HPLC) molecularly imprinted polymer (MIP) CHENG,T. C HUANG,Y. T CHANG,C. Y YAO,K. S HWANG,C.C MOLECULAR RECOGNITION OF SULFAQUINOXALINE AND SULFAPYRIDINE WITH MOLECULARLY IMPRINTED POLYMER
description	The selective separation of sulfapyridine (SPD) from sulfaquinoxaline (SQX) is investigated by applying high performance liquid chromatography (HPLC) with molecularly imprinted polymer (MIP) as the stationary phase. Herein we report the synthesis of a molecularly imprinting polymer, SPD-MIP, by free radical polymerization process. Because of this powerful method synthetic polymers with specific binding sites to template molecule are provided. In addition, the separation performances were represented by using buffer/acetonitrile (3/2, v/v) as mobile phase under 272 nm UV detection. In order to compare the chromatographic data from the stationary phase, capacity factor (k') and separation factors (á) were given. The value of 2.71 (á) revealed that the MIP was able to recognize structurally subtle differences from the template molecule. Our results are discussed with regard to the amount of template, the composition of the chromatographic mobile phase and adsorption capacity.
author	CHENG,T. C HUANG,Y. T CHANG,C. Y YAO,K. S HWANG,C.C
author_facet	CHENG,T. C HUANG,Y. T CHANG,C. Y YAO,K. S HWANG,C.C
author_sort	CHENG,T. C
title	MOLECULAR RECOGNITION OF SULFAQUINOXALINE AND SULFAPYRIDINE WITH MOLECULARLY IMPRINTED POLYMER
title_short	MOLECULAR RECOGNITION OF SULFAQUINOXALINE AND SULFAPYRIDINE WITH MOLECULARLY IMPRINTED POLYMER
title_full	MOLECULAR RECOGNITION OF SULFAQUINOXALINE AND SULFAPYRIDINE WITH MOLECULARLY IMPRINTED POLYMER
title_fullStr	MOLECULAR RECOGNITION OF SULFAQUINOXALINE AND SULFAPYRIDINE WITH MOLECULARLY IMPRINTED POLYMER
title_full_unstemmed	MOLECULAR RECOGNITION OF SULFAQUINOXALINE AND SULFAPYRIDINE WITH MOLECULARLY IMPRINTED POLYMER
title_sort	molecular recognition of sulfaquinoxaline and sulfapyridine with molecularly imprinted polymer
publisher	Sociedad Chilena de Química
publishDate	2009
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072009000300019
work_keys_str_mv	AT chengtc molecularrecognitionofsulfaquinoxalineandsulfapyridinewithmolecularlyimprintedpolymer AT huangyt molecularrecognitionofsulfaquinoxalineandsulfapyridinewithmolecularlyimprintedpolymer AT changcy molecularrecognitionofsulfaquinoxalineandsulfapyridinewithmolecularlyimprintedpolymer AT yaoks molecularrecognitionofsulfaquinoxalineandsulfapyridinewithmolecularlyimprintedpolymer AT hwangcc molecularrecognitionofsulfaquinoxalineandsulfapyridinewithmolecularlyimprintedpolymer
_version_	1718445409170358272

MOLECULAR RECOGNITION OF SULFAQUINOXALINE AND SULFAPYRIDINE WITH MOLECULARLY IMPRINTED POLYMER

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