SYNTHESIS, CHARACTERIZATION AND ANTI-MICROBIAL ACTIVITY OF NEW STEROIDAL CHOLEST-5-EN-7-ONE DERIVATIVES FUSED WITH SUBSTITUTED PYRAZOLINE RING

SYNTHESIS, CHARACTERIZATION AND ANTI-MICROBIAL ACTIVITY OF NEW STEROIDAL CHOLEST-5-EN-7-ONE DERIVATIVES FUSED WITH SUBSTITUTED PYRAZOLINE RING

The reaction of cholest-5-en-7-one (1), its 3β-acetoxy (2) and 3β-chloro (3) analogues with thiosemicarbazide in sodium ethoxide affords 2'-thiocarbamoyl-cholest [5,7-cd] pyrazoline (4), 2'-thiocarbamoyl-3β-acetoxycholest [5,7-cd] pyrazoline (5), and 2'-thio...

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Autores principales: SHAMSUZZAMAN, SHAHEEN KHAN,MOHD, ALAM,MAHBOOB
Lenguaje:English
Publicado: Sociedad Chilena de Química 2009
Materias:
thiosemicarbazide
pyrazolines
cholest-5-en-7-one
thiocarbamoyl
anti-bacterial activity
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072009000400010
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