A NOVEL SYNTHESIS OF SUBSTITUTED 4-HYDROXY- 1,8-NAPHTHYRIDINES

Michael addition of 2-aminopyridines with methylpropiolate to afforded the addition compound 1a-g, which on further cyclisation at higher temperature in dowtherm-A to yield cyclised product 2 a-g, with respective yields depends on the nature of the substituents.

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Detalles Bibliográficos
Autores principales: NARENDER,ATMAKURI, LAXMINARAYANA,E, THIRUMALA CHARY,M
Lenguaje:English
Publicado: Sociedad Chilena de Química 2009
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072009000400033
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Descripción
Sumario:Michael addition of 2-aminopyridines with methylpropiolate to afforded the addition compound 1a-g, which on further cyclisation at higher temperature in dowtherm-A to yield cyclised product 2 a-g, with respective yields depends on the nature of the substituents.