NEW AMIDES OF SULPHONAMIDES: SYNTHESIS AND BIOLOGICAL EVALUATION
A series of amide-derivatives has been synthesized by establishing an amide linkage (-CONH-) between appropriate sulphonamide moiety and different 3-(4-substituted-benzoyl) propionic acids through one-pot reaction. The structures of the newly synthesized compounds were established on the basis of mo...
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Sociedad Chilena de Química
2010
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oai:scielo:S0717-970720100001000172010-04-29NEW AMIDES OF SULPHONAMIDES: SYNTHESIS AND BIOLOGICAL EVALUATIONHUSAIN,ASIFAHMAD,AUSAFMUJEEB,MAKHTER,MYMOONA Amide antiinflammatory sulphonamide antibacterial A series of amide-derivatives has been synthesized by establishing an amide linkage (-CONH-) between appropriate sulphonamide moiety and different 3-(4-substituted-benzoyl) propionic acids through one-pot reaction. The structures of the newly synthesized compounds were established on the basis of modern analytical techniques. These amides were evaluated for their antiinflammatory, ulcerogenic and antibacterial activities. Some of the compounds showed good antiinflammatory activity. Additionally, these derivatives were very low in their ulcerogenic action.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.55 n.1 20102010-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072010000100017en10.4067/S0717-97072010000100017 |
institution |
Scielo Chile |
collection |
Scielo Chile |
language |
English |
topic |
Amide antiinflammatory sulphonamide antibacterial |
spellingShingle |
Amide antiinflammatory sulphonamide antibacterial HUSAIN,ASIF AHMAD,AUSAF MUJEEB,M AKHTER,MYMOONA NEW AMIDES OF SULPHONAMIDES: SYNTHESIS AND BIOLOGICAL EVALUATION |
description |
A series of amide-derivatives has been synthesized by establishing an amide linkage (-CONH-) between appropriate sulphonamide moiety and different 3-(4-substituted-benzoyl) propionic acids through one-pot reaction. The structures of the newly synthesized compounds were established on the basis of modern analytical techniques. These amides were evaluated for their antiinflammatory, ulcerogenic and antibacterial activities. Some of the compounds showed good antiinflammatory activity. Additionally, these derivatives were very low in their ulcerogenic action. |
author |
HUSAIN,ASIF AHMAD,AUSAF MUJEEB,M AKHTER,MYMOONA |
author_facet |
HUSAIN,ASIF AHMAD,AUSAF MUJEEB,M AKHTER,MYMOONA |
author_sort |
HUSAIN,ASIF |
title |
NEW AMIDES OF SULPHONAMIDES: SYNTHESIS AND BIOLOGICAL EVALUATION |
title_short |
NEW AMIDES OF SULPHONAMIDES: SYNTHESIS AND BIOLOGICAL EVALUATION |
title_full |
NEW AMIDES OF SULPHONAMIDES: SYNTHESIS AND BIOLOGICAL EVALUATION |
title_fullStr |
NEW AMIDES OF SULPHONAMIDES: SYNTHESIS AND BIOLOGICAL EVALUATION |
title_full_unstemmed |
NEW AMIDES OF SULPHONAMIDES: SYNTHESIS AND BIOLOGICAL EVALUATION |
title_sort |
new amides of sulphonamides: synthesis and biological evaluation |
publisher |
Sociedad Chilena de Química |
publishDate |
2010 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072010000100017 |
work_keys_str_mv |
AT husainasif newamidesofsulphonamidessynthesisandbiologicalevaluation AT ahmadausaf newamidesofsulphonamidessynthesisandbiologicalevaluation AT mujeebm newamidesofsulphonamidessynthesisandbiologicalevaluation AT akhtermymoona newamidesofsulphonamidessynthesisandbiologicalevaluation |
_version_ |
1718445420639682560 |