NEW AMIDES OF SULPHONAMIDES: SYNTHESIS AND BIOLOGICAL EVALUATION

A series of amide-derivatives has been synthesized by establishing an amide linkage (-CONH-) between appropriate sulphonamide moiety and different 3-(4-substituted-benzoyl) propionic acids through one-pot reaction. The structures of the newly synthesized compounds were established on the basis of mo...

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Autores principales:	HUSAIN,ASIF, AHMAD,AUSAF, MUJEEB,M, AKHTER,MYMOONA
Lenguaje:	English
Publicado:	Sociedad Chilena de Química 2010
Materias:	Amide antiinflammatory sulphonamide antibacterial
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072010000100017
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spelling	oai:scielo:S0717-970720100001000172010-04-29NEW AMIDES OF SULPHONAMIDES: SYNTHESIS AND BIOLOGICAL EVALUATIONHUSAIN,ASIFAHMAD,AUSAFMUJEEB,MAKHTER,MYMOONA Amide antiinflammatory sulphonamide antibacterial A series of amide-derivatives has been synthesized by establishing an amide linkage (-CONH-) between appropriate sulphonamide moiety and different 3-(4-substituted-benzoyl) propionic acids through one-pot reaction. The structures of the newly synthesized compounds were established on the basis of modern analytical techniques. These amides were evaluated for their antiinflammatory, ulcerogenic and antibacterial activities. Some of the compounds showed good antiinflammatory activity. Additionally, these derivatives were very low in their ulcerogenic action.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.55 n.1 20102010-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072010000100017en10.4067/S0717-97072010000100017
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Amide antiinflammatory sulphonamide antibacterial
spellingShingle	Amide antiinflammatory sulphonamide antibacterial HUSAIN,ASIF AHMAD,AUSAF MUJEEB,M AKHTER,MYMOONA NEW AMIDES OF SULPHONAMIDES: SYNTHESIS AND BIOLOGICAL EVALUATION
description	A series of amide-derivatives has been synthesized by establishing an amide linkage (-CONH-) between appropriate sulphonamide moiety and different 3-(4-substituted-benzoyl) propionic acids through one-pot reaction. The structures of the newly synthesized compounds were established on the basis of modern analytical techniques. These amides were evaluated for their antiinflammatory, ulcerogenic and antibacterial activities. Some of the compounds showed good antiinflammatory activity. Additionally, these derivatives were very low in their ulcerogenic action.
author	HUSAIN,ASIF AHMAD,AUSAF MUJEEB,M AKHTER,MYMOONA
author_facet	HUSAIN,ASIF AHMAD,AUSAF MUJEEB,M AKHTER,MYMOONA
author_sort	HUSAIN,ASIF
title	NEW AMIDES OF SULPHONAMIDES: SYNTHESIS AND BIOLOGICAL EVALUATION
title_short	NEW AMIDES OF SULPHONAMIDES: SYNTHESIS AND BIOLOGICAL EVALUATION
title_full	NEW AMIDES OF SULPHONAMIDES: SYNTHESIS AND BIOLOGICAL EVALUATION
title_fullStr	NEW AMIDES OF SULPHONAMIDES: SYNTHESIS AND BIOLOGICAL EVALUATION
title_full_unstemmed	NEW AMIDES OF SULPHONAMIDES: SYNTHESIS AND BIOLOGICAL EVALUATION
title_sort	new amides of sulphonamides: synthesis and biological evaluation
publisher	Sociedad Chilena de Química
publishDate	2010
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072010000100017
work_keys_str_mv	AT husainasif newamidesofsulphonamidessynthesisandbiologicalevaluation AT ahmadausaf newamidesofsulphonamidessynthesisandbiologicalevaluation AT mujeebm newamidesofsulphonamidessynthesisandbiologicalevaluation AT akhtermymoona newamidesofsulphonamidessynthesisandbiologicalevaluation
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NEW AMIDES OF SULPHONAMIDES: SYNTHESIS AND BIOLOGICAL EVALUATION

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