ANODIC SYNTHESIS, SPECTRAL CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF NOVEL 2-AMINO-5-SUBSTITUTED-1,3,4-OXADIAZOLES

Synthesis of 2-amino-5-substituted-1,3,4-oxadiazoles through the electrochemical oxidation of semicarbazone was carried out at platinum anode at room temperature under controlled potential electrolysis in an undivided cell assembly. The electrolysis were carried out in the non aqueous medium acetic...

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Autor principal:	KUMAR,SANJEEV
Lenguaje:	English
Publicado:	Sociedad Chilena de Química 2010
Materias:	Semicarbazone Oxadiazoles Electrolysis Antimicrobial studies
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072010000100030
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spelling	oai:scielo:S0717-970720100001000302010-04-29ANODIC SYNTHESIS, SPECTRAL CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF NOVEL 2-AMINO-5-SUBSTITUTED-1,3,4-OXADIAZOLESKUMAR,SANJEEV Semicarbazone Oxadiazoles Electrolysis Antimicrobial studies Synthesis of 2-amino-5-substituted-1,3,4-oxadiazoles through the electrochemical oxidation of semicarbazone was carried out at platinum anode at room temperature under controlled potential electrolysis in an undivided cell assembly. The electrolysis were carried out in the non aqueous medium acetic acid and lithium perchlorate was used as a supporting electrolyte. The antimicrobial activities of the compounds have been studied by screening the compounds against two gram negative organisms Klebsiella pneumoniae, Escherichia coli, and two gram positive organisms Bacillus subtilis and Streptococcus aureus and antifungal activity against Aspergillus niger and Crysosporium pannical and results have been compared with the standard antibacterial Streptomycin and antifungal Griseofulvin.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.55 n.1 20102010-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072010000100030en10.4067/S0717-97072010000100030
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Semicarbazone Oxadiazoles Electrolysis Antimicrobial studies
spellingShingle	Semicarbazone Oxadiazoles Electrolysis Antimicrobial studies KUMAR,SANJEEV ANODIC SYNTHESIS, SPECTRAL CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF NOVEL 2-AMINO-5-SUBSTITUTED-1,3,4-OXADIAZOLES
description	Synthesis of 2-amino-5-substituted-1,3,4-oxadiazoles through the electrochemical oxidation of semicarbazone was carried out at platinum anode at room temperature under controlled potential electrolysis in an undivided cell assembly. The electrolysis were carried out in the non aqueous medium acetic acid and lithium perchlorate was used as a supporting electrolyte. The antimicrobial activities of the compounds have been studied by screening the compounds against two gram negative organisms Klebsiella pneumoniae, Escherichia coli, and two gram positive organisms Bacillus subtilis and Streptococcus aureus and antifungal activity against Aspergillus niger and Crysosporium pannical and results have been compared with the standard antibacterial Streptomycin and antifungal Griseofulvin.
author	KUMAR,SANJEEV
author_facet	KUMAR,SANJEEV
author_sort	KUMAR,SANJEEV
title	ANODIC SYNTHESIS, SPECTRAL CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF NOVEL 2-AMINO-5-SUBSTITUTED-1,3,4-OXADIAZOLES
title_short	ANODIC SYNTHESIS, SPECTRAL CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF NOVEL 2-AMINO-5-SUBSTITUTED-1,3,4-OXADIAZOLES
title_full	ANODIC SYNTHESIS, SPECTRAL CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF NOVEL 2-AMINO-5-SUBSTITUTED-1,3,4-OXADIAZOLES
title_fullStr	ANODIC SYNTHESIS, SPECTRAL CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF NOVEL 2-AMINO-5-SUBSTITUTED-1,3,4-OXADIAZOLES
title_full_unstemmed	ANODIC SYNTHESIS, SPECTRAL CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF NOVEL 2-AMINO-5-SUBSTITUTED-1,3,4-OXADIAZOLES
title_sort	anodic synthesis, spectral characterization and antimicrobial activity of novel 2-amino-5-substituted-1,3,4-oxadiazoles
publisher	Sociedad Chilena de Química
publishDate	2010
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072010000100030
work_keys_str_mv	AT kumarsanjeev anodicsynthesisspectralcharacterizationandantimicrobialactivityofnovel2amino5substituted134oxadiazoles
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ANODIC SYNTHESIS, SPECTRAL CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF NOVEL 2-AMINO-5-SUBSTITUTED-1,3,4-OXADIAZOLES

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