SYNTHESIS, SPECTROSCOPIC CHARACTERIZATION AND ANTIBACTERIAL ACTIVITY OF SOME CHLOROSULPHOXIDE RUTHENIUM (II) AND RUTHENIUM (III) COMPLEXES OF 4-(BENZYLIDENEAMINO)-1,2-DIMETHYL-2-PHENYL-1,2-DIHYDROPYRAZOLE-3-ONE, SCHIFF BASE
In present work we report the synthesis of five complexes of three different formulations, viz. [cis-RuCl2(SBANTP)2]; [trans-RuCl2(SBANTP)2]; and [RuCl4(SBANTP)-][X]+; where [X]+ = [(dmso)2H]+, Na+ or [(tmso)H]+and SBANTP = 4-(benzyideneamino)-1,5-dimethyl-2-phenyl-l,2-dihydropyrazole-3-one, from di...
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| Autores principales: | , , , , , , , , |
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| Lenguaje: | English |
| Publicado: |
Sociedad Chilena de Química
2010
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| Materias: | |
| Acceso en línea: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072010000200003 |
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| Sumario: | In present work we report the synthesis of five complexes of three different formulations, viz. [cis-RuCl2(SBANTP)2]; [trans-RuCl2(SBANTP)2]; and [RuCl4(SBANTP)-][X]+; where [X]+ = [(dmso)2H]+, Na+ or [(tmso)H]+and SBANTP = 4-(benzyideneamino)-1,5-dimethyl-2-phenyl-l,2-dihydropyrazole-3-one, from different routes. The complexes were characterized on the basis of elemental analyses, molar conductance measurements, magnetic susceptibility, electronic spectra, FTIR, ¹H-NMR,13C{¹H}NMR spectroscopy, FAB-Mass spectrometry. Complex 2 was also analyzed by EDX analysis.The 3D molecular modeling and analysis for bond length and bond angle have been also carried out for one of the representative complex 1. AU the five complexes were screened for antibacterial activity and found to be more potent against gram negative bacteria Escherichia coli than their precursora but less active than chloramphenicol. |
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