AUTOMATIC MULTISYRINGE FLOW INJECTION SYSTEM FOR THE SPECTROPHOTOMETRIC DETERMINATION OF TINIDAZOLE IN PHARMACEUTICAL PREPARATIONS

A multisyringe flow injection analysis (MSFIA) method for the determination of tinidazole (TNZ) in pharmaceutical preparations was developed. TNZ concentrations were determined by spectrophotometric detection at 374 nm wavelength using a light emitting diode (LED). The MSFIA parameters were optimize...

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Autores principales:	GUZMÁN-MAR,J.L, HINOJOZA-REYES,L, HERNANDEZ-RAMÍREZ,A, PERALTA-HERNANDEZ,J.M, LÓPEZ-CHUKEN,V.J, LÓPEZ-DE-ALBA,P.L, CERDA-MARTÍN,V
Lenguaje:	English
Publicado:	Sociedad Chilena de Química 2010
Materias:	Multisyringe flow injection analysis (MSFIA) tinidazole (TNZ) alkaline hydrolysis pharmaceutical formulations
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072010000200015
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spelling	oai:scielo:S0717-970720100002000152010-09-06AUTOMATIC MULTISYRINGE FLOW INJECTION SYSTEM FOR THE SPECTROPHOTOMETRIC DETERMINATION OF TINIDAZOLE IN PHARMACEUTICAL PREPARATIONSGUZMÁN-MAR,J.LHINOJOZA-REYES,LHERNANDEZ-RAMÍREZ,APERALTA-HERNANDEZ,J.MLÓPEZ-CHUKEN,V.JLÓPEZ-DE-ALBA,P.LCERDA-MARTÍN,V Multisyringe flow injection analysis (MSFIA) tinidazole (TNZ) alkaline hydrolysis pharmaceutical formulations A multisyringe flow injection analysis (MSFIA) method for the determination of tinidazole (TNZ) in pharmaceutical preparations was developed. TNZ concentrations were determined by spectrophotometric detection at 374 nm wavelength using a light emitting diode (LED). The MSFIA parameters were optimized. Under the optimized experimental conditions, a linear dynamic range from 2 to 56 mg L-1 TNZ, a 3σ detection limit of 0.3 mg L-1, and a 10o quantification limit of 1.2 mg L-1 were obtained. The relative standard deviation (%R.S.D.) at 2, 28 and 56 mg L-1 was 2.3, 1.4 and 0.9%, respectively (n = 10). A sample throughput of 76 determinations/h was achieved.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.55 n.2 20102010-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072010000200015en10.4067/S0717-97072010000200015
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Multisyringe flow injection analysis (MSFIA) tinidazole (TNZ) alkaline hydrolysis pharmaceutical formulations
spellingShingle	Multisyringe flow injection analysis (MSFIA) tinidazole (TNZ) alkaline hydrolysis pharmaceutical formulations GUZMÁN-MAR,J.L HINOJOZA-REYES,L HERNANDEZ-RAMÍREZ,A PERALTA-HERNANDEZ,J.M LÓPEZ-CHUKEN,V.J LÓPEZ-DE-ALBA,P.L CERDA-MARTÍN,V AUTOMATIC MULTISYRINGE FLOW INJECTION SYSTEM FOR THE SPECTROPHOTOMETRIC DETERMINATION OF TINIDAZOLE IN PHARMACEUTICAL PREPARATIONS
description	A multisyringe flow injection analysis (MSFIA) method for the determination of tinidazole (TNZ) in pharmaceutical preparations was developed. TNZ concentrations were determined by spectrophotometric detection at 374 nm wavelength using a light emitting diode (LED). The MSFIA parameters were optimized. Under the optimized experimental conditions, a linear dynamic range from 2 to 56 mg L-1 TNZ, a 3σ detection limit of 0.3 mg L-1, and a 10o quantification limit of 1.2 mg L-1 were obtained. The relative standard deviation (%R.S.D.) at 2, 28 and 56 mg L-1 was 2.3, 1.4 and 0.9%, respectively (n = 10). A sample throughput of 76 determinations/h was achieved.
author	GUZMÁN-MAR,J.L HINOJOZA-REYES,L HERNANDEZ-RAMÍREZ,A PERALTA-HERNANDEZ,J.M LÓPEZ-CHUKEN,V.J LÓPEZ-DE-ALBA,P.L CERDA-MARTÍN,V
author_facet	GUZMÁN-MAR,J.L HINOJOZA-REYES,L HERNANDEZ-RAMÍREZ,A PERALTA-HERNANDEZ,J.M LÓPEZ-CHUKEN,V.J LÓPEZ-DE-ALBA,P.L CERDA-MARTÍN,V
author_sort	GUZMÁN-MAR,J.L
title	AUTOMATIC MULTISYRINGE FLOW INJECTION SYSTEM FOR THE SPECTROPHOTOMETRIC DETERMINATION OF TINIDAZOLE IN PHARMACEUTICAL PREPARATIONS
title_short	AUTOMATIC MULTISYRINGE FLOW INJECTION SYSTEM FOR THE SPECTROPHOTOMETRIC DETERMINATION OF TINIDAZOLE IN PHARMACEUTICAL PREPARATIONS
title_full	AUTOMATIC MULTISYRINGE FLOW INJECTION SYSTEM FOR THE SPECTROPHOTOMETRIC DETERMINATION OF TINIDAZOLE IN PHARMACEUTICAL PREPARATIONS
title_fullStr	AUTOMATIC MULTISYRINGE FLOW INJECTION SYSTEM FOR THE SPECTROPHOTOMETRIC DETERMINATION OF TINIDAZOLE IN PHARMACEUTICAL PREPARATIONS
title_full_unstemmed	AUTOMATIC MULTISYRINGE FLOW INJECTION SYSTEM FOR THE SPECTROPHOTOMETRIC DETERMINATION OF TINIDAZOLE IN PHARMACEUTICAL PREPARATIONS
title_sort	automatic multisyringe flow injection system for the spectrophotometric determination of tinidazole in pharmaceutical preparations
publisher	Sociedad Chilena de Química
publishDate	2010
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072010000200015
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AUTOMATIC MULTISYRINGE FLOW INJECTION SYSTEM FOR THE SPECTROPHOTOMETRIC DETERMINATION OF TINIDAZOLE IN PHARMACEUTICAL PREPARATIONS

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