SYNTHESIS AND SPECTRAL ANALYSIS OF AN ARRAY OF NOVEL 4-(4-MORPHOLINOPHENYL)-6-ARYL-PYRIMIDIN-2-AMINES

SYNTHESIS AND SPECTRAL ANALYSIS OF AN ARRAY OF NOVEL 4-(4-MORPHOLINOPHENYL)-6-ARYL-PYRIMIDIN-2-AMINES

An array of newly synthesized novel 4-(4-morpholinophenyl)-6-arylpyrimidin-2-amines (20-28) are synthesized from the respective (E)-1-4-morpholinophenyl)-3-aryl-prop-2-en-1-ones (11-19) by the treatment of guanidine nitrate in refluxing ethanol catalyzed by lithium hydroxide and characterized by mel...

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Detalles Bibliográficos
Autores principales: THANUSU,J, KANAGARAJAN,V, GOPALAKRISHNAN,M
Lenguaje:English
Publicado: Sociedad Chilena de Química 2010
Materias:
1-(4-morpholinophenyl) ethanone
(E)-1-4-morpholinophenyl)-3-aryl-prop-2-en-1-ones
4-(4-morpholinophenyl)-6-arylpyrimidin-2-amines
Guanidine nitrate
Synthesis
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072010000400022
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Sumario:An array of newly synthesized novel 4-(4-morpholinophenyl)-6-arylpyrimidin-2-amines (20-28) are synthesized from the respective (E)-1-4-morpholinophenyl)-3-aryl-prop-2-en-1-ones (11-19) by the treatment of guanidine nitrate in refluxing ethanol catalyzed by lithium hydroxide and characterized by melting point, elemental analysis, MS, FT-IR, one-dimensional NMR (¹H & 13C) spectroscopic data.

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