SPECTROPHOTOMETRYC DETERMINATION OF SERTRALINE IN PURE AND BLOOD SAMPLE

A simple and sensitive spectrophotomteric method has been developed for the determination of Sertraline in pharmaceutical and blood sample. The current method is depend upon the reaction between the sertraline and chloranilic acid in slightly alkaline medium, giving a purple colour complex having ma...

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Autores principales:	JAHANGIR,MUHAMMAD, RIAZ,FAISAL, CHAUDHRY,ASIF HANIF
Lenguaje:	English
Publicado:	Sociedad Chilena de Química 2011
Materias:	Spectrophotometry Sertraline chloranilic acid Beer's law quantitative estimation
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072011000200004
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spelling	oai:scielo:S0717-970720110002000042011-09-01SPECTROPHOTOMETRYC DETERMINATION OF SERTRALINE IN PURE AND BLOOD SAMPLEJAHANGIR,MUHAMMADRIAZ,FAISALCHAUDHRY,ASIF HANIF Spectrophotometry Sertraline chloranilic acid Beer's law quantitative estimation A simple and sensitive spectrophotomteric method has been developed for the determination of Sertraline in pharmaceutical and blood sample. The current method is depend upon the reaction between the sertraline and chloranilic acid in slightly alkaline medium, giving a purple colour complex having maximum absorbance at 527.5 nm. The reaction is selective for sertraline with 0.01mg/mL.The colour reaction obeys Beer's law from 0.1mg to 5mg/mL of sertraline and relative standard deviation is 0.19%. The quantitative estimation of sertraline in blood sample is also studied.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.56 n.2 20112011-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072011000200004en10.4067/S0717-97072011000200004
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Spectrophotometry Sertraline chloranilic acid Beer's law quantitative estimation
spellingShingle	Spectrophotometry Sertraline chloranilic acid Beer's law quantitative estimation JAHANGIR,MUHAMMAD RIAZ,FAISAL CHAUDHRY,ASIF HANIF SPECTROPHOTOMETRYC DETERMINATION OF SERTRALINE IN PURE AND BLOOD SAMPLE
description	A simple and sensitive spectrophotomteric method has been developed for the determination of Sertraline in pharmaceutical and blood sample. The current method is depend upon the reaction between the sertraline and chloranilic acid in slightly alkaline medium, giving a purple colour complex having maximum absorbance at 527.5 nm. The reaction is selective for sertraline with 0.01mg/mL.The colour reaction obeys Beer's law from 0.1mg to 5mg/mL of sertraline and relative standard deviation is 0.19%. The quantitative estimation of sertraline in blood sample is also studied.
author	JAHANGIR,MUHAMMAD RIAZ,FAISAL CHAUDHRY,ASIF HANIF
author_facet	JAHANGIR,MUHAMMAD RIAZ,FAISAL CHAUDHRY,ASIF HANIF
author_sort	JAHANGIR,MUHAMMAD
title	SPECTROPHOTOMETRYC DETERMINATION OF SERTRALINE IN PURE AND BLOOD SAMPLE
title_short	SPECTROPHOTOMETRYC DETERMINATION OF SERTRALINE IN PURE AND BLOOD SAMPLE
title_full	SPECTROPHOTOMETRYC DETERMINATION OF SERTRALINE IN PURE AND BLOOD SAMPLE
title_fullStr	SPECTROPHOTOMETRYC DETERMINATION OF SERTRALINE IN PURE AND BLOOD SAMPLE
title_full_unstemmed	SPECTROPHOTOMETRYC DETERMINATION OF SERTRALINE IN PURE AND BLOOD SAMPLE
title_sort	spectrophotometryc determination of sertraline in pure and blood sample
publisher	Sociedad Chilena de Química
publishDate	2011
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072011000200004
work_keys_str_mv	AT jahangirmuhammad spectrophotometrycdeterminationofsertralineinpureandbloodsample AT riazfaisal spectrophotometrycdeterminationofsertralineinpureandbloodsample AT chaudhryasifhanif spectrophotometrycdeterminationofsertralineinpureandbloodsample
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SPECTROPHOTOMETRYC DETERMINATION OF SERTRALINE IN PURE AND BLOOD SAMPLE

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