VALIDATED CHIRAL LC METHOD FOR DEXRABEPRAZOLE ON REVERSE PHASE AMYLOSE BASED STATIONARY PHASE

VALIDATED CHIRAL LC METHOD FOR DEXRABEPRAZOLE ON REVERSE PHASE AMYLOSE BASED STATIONARY PHASE

A simple, rapid and robust LC method was developed and validated for the enantiomeric separation of dexrabeprazole in bulk drug and formulation. The enantiomers of dexrabeprazole were resolved on a Chiralpak AD-RH (amylose based stationary phase) column using a mobile phase consisting of water: acet...

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Autores principales: PATIL,KIRAN R, RANE,VIPUL P, YEOLE,RAVINDRA D, SANGSHETTI,JAIPRAKASH N, SHINDE,DEVANAND B
Lenguaje:English
Publicado: Sociedad Chilena de Química 2011
Materias:
Dexrabeprazole
Chiral HPLC
Enantiomer
Validation
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072011000200018
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