X-RAY STUDIES AND ANTIBACTERIAL ACTIVITY IN COPPER AND COBALT COMPLEXES WITH IMIDAZOLE DERIVATIVE LIGANDS

The complexes Diaqua-bis(5-nitroimidazole)-copper(II)-dinitrate (1); Tetrakis(4- phenylimidazole)-copper(II)-dinitrate, ethanol solvate (2); Bis(4-phenylimidazole)-bis(acetate)-copper(II) (3); Hexakis(4-phenylimidazole)-cobalt(II)-acetate (4) and Bis(2- phenylimidazole)-bis(acetate)-cobalt(II) (5),...

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Autores principales:	ATRIA,ANA MARÍA, CORTÉS-CORTÉS,PIEDAD, GARLAND,MARÍA TERESA, BAGGIO,RICARDO, MORALES,KARINA, SOTO,MAURICIO, CORSINI,GINO
Lenguaje:	English
Publicado:	Sociedad Chilena de Química 2011
Materias:	copper cobalt crystal structure antibacterial activities
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072011000300015
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spelling	oai:scielo:S0717-970720110003000152012-01-11X-RAY STUDIES AND ANTIBACTERIAL ACTIVITY IN COPPER AND COBALT COMPLEXES WITH IMIDAZOLE DERIVATIVE LIGANDSATRIA,ANA MARÍACORTÉS-CORTÉS,PIEDADGARLAND,MARÍA TERESABAGGIO,RICARDOMORALES,KARINASOTO,MAURICIOCORSINI,GINO copper cobalt crystal structure antibacterial activities The complexes Diaqua-bis(5-nitroimidazole)-copper(II)-dinitrate (1); Tetrakis(4- phenylimidazole)-copper(II)-dinitrate, ethanol solvate (2); Bis(4-phenylimidazole)-bis(acetate)-copper(II) (3); Hexakis(4-phenylimidazole)-cobalt(II)-acetate (4) and Bis(2- phenylimidazole)-bis(acetate)-cobalt(II) (5), have been synthesized. Their structures were determined by X-ray analysis. The antimicrobial activities of these complexes have been screened in vitro against the microorganisms Escherichia coli, Klebsiella pneumoniae, Shigella flexneri, Salmonella typhi, Salmonella enteritidis, Salmonella entérica, Staphylococcus aureus, Listeria monocytogenes. Complexes (1) and (3) showed antimicrobial activity over Gram positive and negative bacteria by a bacteriostatic effect. On the other hand, complexes (4) and (5) showed antibacterial activity with a bacteriolytic effect over Gram positive and negative bacteria. The cytotoxicity of complexes (3) and (4) was tested in vitro. These complexes presented cytotoxic effect to values near the MIC.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.56 n.3 20112011-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072011000300015en10.4067/S0717-97072011000300015
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	copper cobalt crystal structure antibacterial activities
spellingShingle	copper cobalt crystal structure antibacterial activities ATRIA,ANA MARÍA CORTÉS-CORTÉS,PIEDAD GARLAND,MARÍA TERESA BAGGIO,RICARDO MORALES,KARINA SOTO,MAURICIO CORSINI,GINO X-RAY STUDIES AND ANTIBACTERIAL ACTIVITY IN COPPER AND COBALT COMPLEXES WITH IMIDAZOLE DERIVATIVE LIGANDS
description	The complexes Diaqua-bis(5-nitroimidazole)-copper(II)-dinitrate (1); Tetrakis(4- phenylimidazole)-copper(II)-dinitrate, ethanol solvate (2); Bis(4-phenylimidazole)-bis(acetate)-copper(II) (3); Hexakis(4-phenylimidazole)-cobalt(II)-acetate (4) and Bis(2- phenylimidazole)-bis(acetate)-cobalt(II) (5), have been synthesized. Their structures were determined by X-ray analysis. The antimicrobial activities of these complexes have been screened in vitro against the microorganisms Escherichia coli, Klebsiella pneumoniae, Shigella flexneri, Salmonella typhi, Salmonella enteritidis, Salmonella entérica, Staphylococcus aureus, Listeria monocytogenes. Complexes (1) and (3) showed antimicrobial activity over Gram positive and negative bacteria by a bacteriostatic effect. On the other hand, complexes (4) and (5) showed antibacterial activity with a bacteriolytic effect over Gram positive and negative bacteria. The cytotoxicity of complexes (3) and (4) was tested in vitro. These complexes presented cytotoxic effect to values near the MIC.
author	ATRIA,ANA MARÍA CORTÉS-CORTÉS,PIEDAD GARLAND,MARÍA TERESA BAGGIO,RICARDO MORALES,KARINA SOTO,MAURICIO CORSINI,GINO
author_facet	ATRIA,ANA MARÍA CORTÉS-CORTÉS,PIEDAD GARLAND,MARÍA TERESA BAGGIO,RICARDO MORALES,KARINA SOTO,MAURICIO CORSINI,GINO
author_sort	ATRIA,ANA MARÍA
title	X-RAY STUDIES AND ANTIBACTERIAL ACTIVITY IN COPPER AND COBALT COMPLEXES WITH IMIDAZOLE DERIVATIVE LIGANDS
title_short	X-RAY STUDIES AND ANTIBACTERIAL ACTIVITY IN COPPER AND COBALT COMPLEXES WITH IMIDAZOLE DERIVATIVE LIGANDS
title_full	X-RAY STUDIES AND ANTIBACTERIAL ACTIVITY IN COPPER AND COBALT COMPLEXES WITH IMIDAZOLE DERIVATIVE LIGANDS
title_fullStr	X-RAY STUDIES AND ANTIBACTERIAL ACTIVITY IN COPPER AND COBALT COMPLEXES WITH IMIDAZOLE DERIVATIVE LIGANDS
title_full_unstemmed	X-RAY STUDIES AND ANTIBACTERIAL ACTIVITY IN COPPER AND COBALT COMPLEXES WITH IMIDAZOLE DERIVATIVE LIGANDS
title_sort	x-ray studies and antibacterial activity in copper and cobalt complexes with imidazole derivative ligands
publisher	Sociedad Chilena de Química
publishDate	2011
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072011000300015
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X-RAY STUDIES AND ANTIBACTERIAL ACTIVITY IN COPPER AND COBALT COMPLEXES WITH IMIDAZOLE DERIVATIVE LIGANDS

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