SYNTHESIS OF 1-BENZYL-3-[4-(ARYL-1-PIPERAZINYL) CARBONYL]-1H-INDOLES: NOVEL LIGANDS WITH POTENTIAL D4 DOPAMINERGIC ACTIVITY
The synthesis of a series of functionalized 1-Benzyl-3-[4-Aryl-1-piperazingl]carbonyl-1H-Indoles 6(a-f), as a potential new class of bioactive ligands at D4 receptors is reported. The synthetic strategy took place through a five steps sequence to provide indole amides 6(a-f) in 75-92% yield...
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| Auteurs principaux: | , , , , , |
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| Langue: | English |
| Publié: |
Sociedad Chilena de Química
2011
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| Accès en ligne: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072011000400009 |
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