COMPARATIVE STUDIES OF LEWIS ACIDITY OF ALKYL-TIN CHLORIDES IN MULTICOMPONENT BIGINELLI CONDENSATION USING GRINDSTONE CHEMISTRY TECHNIQUE
A simple and efficient procedure for the one pot Biginelli Condensation Reaction of aldehydes, â-ketoester and urea employing SnCl4.5H2O /mono/di/tri-butyl- tin chloride as a novel catalyst is described. Compared to classical Biginelli reaction conditions, the present method has the advantages of go...
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Autores principales: | , , , |
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Lenguaje: | English |
Publicado: |
Sociedad Chilena de Química
2012
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Materias: | |
Acceso en línea: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072012000100013 |
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Sumario: | A simple and efficient procedure for the one pot Biginelli Condensation Reaction of aldehydes, â-ketoester and urea employing SnCl4.5H2O /mono/di/tri-butyl- tin chloride as a novel catalyst is described. Compared to classical Biginelli reaction conditions, the present method has the advantages of good yields, short reaction times and experimental simplicity. Further, comparative efficiency of alkyl- tin chlorides in multicomponent Biginelli Condensation Reaction is also studied under solvent free conditions. |
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