TOTAL AND MAIN As SPECIES PRESENT IN CARDIOVASCULAR TISSUES OF PEOPLE LIVINGIN As CONTAMINATED AREAS

The concentration levels of As in the Chilean II Region of Antofagasta produces non cancer health outcomes such as cardiovascular diseases and in last term heart attack. On this study, the determination of total As content and main inorganic and organoarsenic species found in three heart tissues (au...

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Autores principales:	PIZARRO,ISABEL, ROMÁN-SILVA,DOMINGO, SOLAR,CARLOS, GÓMEZ,MARÍA MILAGROS, CÁMARA,CARMEN, PALACIOS,MARÍA ANTONIA
Lenguaje:	English
Publicado:	Sociedad Chilena de Química 2012
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072012000200027
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spelling	oai:scielo:S0717-970720120002000272014-03-10TOTAL AND MAIN As SPECIES PRESENT IN CARDIOVASCULAR TISSUES OF PEOPLE LIVINGIN As CONTAMINATED AREASPIZARRO,ISABELROMÁN-SILVA,DOMINGOSOLAR,CARLOSGÓMEZ,MARÍA MILAGROSCÁMARA,CARMENPALACIOS,MARÍA ANTONIAThe concentration levels of As in the Chilean II Region of Antofagasta produces non cancer health outcomes such as cardiovascular diseases and in last term heart attack. On this study, the determination of total As content and main inorganic and organoarsenic species found in three heart tissues (auricle, mammary artery and fat) and the saphene vein of people living in the Chilean II Region, suffering coronary thrombosis has been carried out. Comparison with similar tissues of patients from other non-contaminated areas has been undertaken. The extraction of As species occurred in methanol: water (1:1) and As species determination have been used the tandem HPLC-ICP-MS using the Hamilton PRP X100 anion column. For total As determination has been performed by HG-AAS and ICP-MS. The auricle and in less extend the saphene support the higher As concentration (mean values of 7.7 and 2.5 μg g-1, respectively), being As(III) the predominant species. Methylarsonate (MA) and dimethylarsinate (DMA) is not a favoured mechanism. The presence of high total As and high As(III) species content in the auricle and saphene of more contaminated people, the damage found in the saphene tissue and the global characteristics of the people under study in which the As stigmas are present in all of them, suggests that As could be involved in the cardiovascular diseases.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.57 n.2 20122012-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072012000200027en10.4067/S0717-97072012000200027
institution	Scielo Chile
collection	Scielo Chile
language	English
description	The concentration levels of As in the Chilean II Region of Antofagasta produces non cancer health outcomes such as cardiovascular diseases and in last term heart attack. On this study, the determination of total As content and main inorganic and organoarsenic species found in three heart tissues (auricle, mammary artery and fat) and the saphene vein of people living in the Chilean II Region, suffering coronary thrombosis has been carried out. Comparison with similar tissues of patients from other non-contaminated areas has been undertaken. The extraction of As species occurred in methanol: water (1:1) and As species determination have been used the tandem HPLC-ICP-MS using the Hamilton PRP X100 anion column. For total As determination has been performed by HG-AAS and ICP-MS. The auricle and in less extend the saphene support the higher As concentration (mean values of 7.7 and 2.5 μg g-1, respectively), being As(III) the predominant species. Methylarsonate (MA) and dimethylarsinate (DMA) is not a favoured mechanism. The presence of high total As and high As(III) species content in the auricle and saphene of more contaminated people, the damage found in the saphene tissue and the global characteristics of the people under study in which the As stigmas are present in all of them, suggests that As could be involved in the cardiovascular diseases.
author	PIZARRO,ISABEL ROMÁN-SILVA,DOMINGO SOLAR,CARLOS GÓMEZ,MARÍA MILAGROS CÁMARA,CARMEN PALACIOS,MARÍA ANTONIA
spellingShingle	PIZARRO,ISABEL ROMÁN-SILVA,DOMINGO SOLAR,CARLOS GÓMEZ,MARÍA MILAGROS CÁMARA,CARMEN PALACIOS,MARÍA ANTONIA TOTAL AND MAIN As SPECIES PRESENT IN CARDIOVASCULAR TISSUES OF PEOPLE LIVINGIN As CONTAMINATED AREAS
author_facet	PIZARRO,ISABEL ROMÁN-SILVA,DOMINGO SOLAR,CARLOS GÓMEZ,MARÍA MILAGROS CÁMARA,CARMEN PALACIOS,MARÍA ANTONIA
author_sort	PIZARRO,ISABEL
title	TOTAL AND MAIN As SPECIES PRESENT IN CARDIOVASCULAR TISSUES OF PEOPLE LIVINGIN As CONTAMINATED AREAS
title_short	TOTAL AND MAIN As SPECIES PRESENT IN CARDIOVASCULAR TISSUES OF PEOPLE LIVINGIN As CONTAMINATED AREAS
title_full	TOTAL AND MAIN As SPECIES PRESENT IN CARDIOVASCULAR TISSUES OF PEOPLE LIVINGIN As CONTAMINATED AREAS
title_fullStr	TOTAL AND MAIN As SPECIES PRESENT IN CARDIOVASCULAR TISSUES OF PEOPLE LIVINGIN As CONTAMINATED AREAS
title_full_unstemmed	TOTAL AND MAIN As SPECIES PRESENT IN CARDIOVASCULAR TISSUES OF PEOPLE LIVINGIN As CONTAMINATED AREAS
title_sort	total and main as species present in cardiovascular tissues of people livingin as contaminated areas
publisher	Sociedad Chilena de Química
publishDate	2012
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072012000200027
work_keys_str_mv	AT pizarroisabel totalandmainasspeciespresentincardiovasculartissuesofpeoplelivinginascontaminatedareas AT romansilvadomingo totalandmainasspeciespresentincardiovasculartissuesofpeoplelivinginascontaminatedareas AT solarcarlos totalandmainasspeciespresentincardiovasculartissuesofpeoplelivinginascontaminatedareas AT gomezmariamilagros totalandmainasspeciespresentincardiovasculartissuesofpeoplelivinginascontaminatedareas AT camaracarmen totalandmainasspeciespresentincardiovasculartissuesofpeoplelivinginascontaminatedareas AT palaciosmariaantonia totalandmainasspeciespresentincardiovasculartissuesofpeoplelivinginascontaminatedareas
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TOTAL AND MAIN As SPECIES PRESENT IN CARDIOVASCULAR TISSUES OF PEOPLE LIVINGIN As CONTAMINATED AREAS

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