SYNTHESIS, CRYSTAL STRUCTURE AND ANTIOXIDANT POTENTIAL OF DI-(TV-CINNAMYL) FLUOXETINE CHLORIDE

A new derivative of Fluoxetine, N,N-dicinnamyl-N-methyl-3-phenyl-3- [4-(trifluoromethyl) phenoxy]butan-1-aminium chloride hydrate [Di-(N-Cinnamyl) Fluoxetine Chloride hydrate] was synthesized and characterized by single-crystal X-ray diffraction studies, elemental analyzer, thermogravimetric and FTI...

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Autores principales:	KANWAL,NOSHEEN, SAHIN,ONUR, HUSAAIN,ERUM A, ULLAHKHAN,ISLAM, BUYUKGUNGOR,ORHAN
Lenguaje:	English
Publicado:	Sociedad Chilena de Química 2013
Materias:	Fluoxetine Derivative Crystal structure Antioxidant activity
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072013000100001
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:scielo:S0717-970720130001000012014-09-09SYNTHESIS, CRYSTAL STRUCTURE AND ANTIOXIDANT POTENTIAL OF DI-(TV-CINNAMYL) FLUOXETINE CHLORIDEKANWAL,NOSHEENSAHIN,ONURHUSAAIN,ERUM AULLAHKHAN,ISLAMBUYUKGUNGOR,ORHAN Fluoxetine Derivative Crystal structure Antioxidant activity A new derivative of Fluoxetine, N,N-dicinnamyl-N-methyl-3-phenyl-3- [4-(trifluoromethyl) phenoxy]butan-1-aminium chloride hydrate [Di-(N-Cinnamyl) Fluoxetine Chloride hydrate] was synthesized and characterized by single-crystal X-ray diffraction studies, elemental analyzer, thermogravimetric and FTIR spectroscopy analysis. The titled compound [C35H37ClF3NO2] crystallized in monoclinic, having unit cell parameters a = 19.155(14) A°, b = 9.193(5) A°, c = 18.596(13) A° and belongs to P2(1)/c space group. The molecule shows disorder of F atoms and was modeled as two different orientations. The one-dimensional crystal packing features weak C-H … π interactions showing the formation of a chain along [001], provides stability to the crystal lattice. Antioxidant potential of Di-(N-Cinnamyl) Fluoxetine Chloride hydrate has been described and was found higher than Fluoxetine and N-Benzyl Fluoxetine.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.58 n.1 20132013-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072013000100001en10.4067/S0717-97072013000100001
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Fluoxetine Derivative Crystal structure Antioxidant activity
spellingShingle	Fluoxetine Derivative Crystal structure Antioxidant activity KANWAL,NOSHEEN SAHIN,ONUR HUSAAIN,ERUM A ULLAHKHAN,ISLAM BUYUKGUNGOR,ORHAN SYNTHESIS, CRYSTAL STRUCTURE AND ANTIOXIDANT POTENTIAL OF DI-(TV-CINNAMYL) FLUOXETINE CHLORIDE
description	A new derivative of Fluoxetine, N,N-dicinnamyl-N-methyl-3-phenyl-3- [4-(trifluoromethyl) phenoxy]butan-1-aminium chloride hydrate [Di-(N-Cinnamyl) Fluoxetine Chloride hydrate] was synthesized and characterized by single-crystal X-ray diffraction studies, elemental analyzer, thermogravimetric and FTIR spectroscopy analysis. The titled compound [C35H37ClF3NO2] crystallized in monoclinic, having unit cell parameters a = 19.155(14) A°, b = 9.193(5) A°, c = 18.596(13) A° and belongs to P2(1)/c space group. The molecule shows disorder of F atoms and was modeled as two different orientations. The one-dimensional crystal packing features weak C-H … π interactions showing the formation of a chain along [001], provides stability to the crystal lattice. Antioxidant potential of Di-(N-Cinnamyl) Fluoxetine Chloride hydrate has been described and was found higher than Fluoxetine and N-Benzyl Fluoxetine.
author	KANWAL,NOSHEEN SAHIN,ONUR HUSAAIN,ERUM A ULLAHKHAN,ISLAM BUYUKGUNGOR,ORHAN
author_facet	KANWAL,NOSHEEN SAHIN,ONUR HUSAAIN,ERUM A ULLAHKHAN,ISLAM BUYUKGUNGOR,ORHAN
author_sort	KANWAL,NOSHEEN
title	SYNTHESIS, CRYSTAL STRUCTURE AND ANTIOXIDANT POTENTIAL OF DI-(TV-CINNAMYL) FLUOXETINE CHLORIDE
title_short	SYNTHESIS, CRYSTAL STRUCTURE AND ANTIOXIDANT POTENTIAL OF DI-(TV-CINNAMYL) FLUOXETINE CHLORIDE
title_full	SYNTHESIS, CRYSTAL STRUCTURE AND ANTIOXIDANT POTENTIAL OF DI-(TV-CINNAMYL) FLUOXETINE CHLORIDE
title_fullStr	SYNTHESIS, CRYSTAL STRUCTURE AND ANTIOXIDANT POTENTIAL OF DI-(TV-CINNAMYL) FLUOXETINE CHLORIDE
title_full_unstemmed	SYNTHESIS, CRYSTAL STRUCTURE AND ANTIOXIDANT POTENTIAL OF DI-(TV-CINNAMYL) FLUOXETINE CHLORIDE
title_sort	synthesis, crystal structure and antioxidant potential of di-(tv-cinnamyl) fluoxetine chloride
publisher	Sociedad Chilena de Química
publishDate	2013
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072013000100001
work_keys_str_mv	AT kanwalnosheen synthesiscrystalstructureandantioxidantpotentialofditvcinnamylfluoxetinechloride AT sahinonur synthesiscrystalstructureandantioxidantpotentialofditvcinnamylfluoxetinechloride AT husaaineruma synthesiscrystalstructureandantioxidantpotentialofditvcinnamylfluoxetinechloride AT ullahkhanislam synthesiscrystalstructureandantioxidantpotentialofditvcinnamylfluoxetinechloride AT buyukgungororhan synthesiscrystalstructureandantioxidantpotentialofditvcinnamylfluoxetinechloride
_version_	1718445478922682368

SYNTHESIS, CRYSTAL STRUCTURE AND ANTIOXIDANT POTENTIAL OF DI-(TV-CINNAMYL) FLUOXETINE CHLORIDE

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