SYNTHESIS, SPECTROSCOPIC CHARACTERIZATION AND X-RAY ANALYSIS OF 6-NITROQUINAZOLINE-2,4(1H,3H)-DIONE
In this work, 6-nitroquinazoline-2,4(1H,3H)-dione was obtained in two step with good yields using a facile synthetic method. Its structure was characterized by X-ray single crystal diffraction technique (XRD), IR, 1D-NMR (¹H-NMR and 13C-NMR) and 2D-NMR (H-H COSY and H-C HMBC) spectroscopy. All N and...
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Sociedad Chilena de Química
2013
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oai:scielo:S0717-970720130003000042014-09-09SYNTHESIS, SPECTROSCOPIC CHARACTERIZATION AND X-RAY ANALYSIS OF 6-NITROQUINAZOLINE-2,4(1H,3H)-DIONEKESTERNICH,VÍCTORPÉREZ-FEHRMANN,MARCIAORTÍZ,SERGIOVERDUGO,FELIPEBRITO,IVÁNBOLTE,MICHAELCÁRDENAS,ALEJANDROIn this work, 6-nitroquinazoline-2,4(1H,3H)-dione was obtained in two step with good yields using a facile synthetic method. Its structure was characterized by X-ray single crystal diffraction technique (XRD), IR, 1D-NMR (¹H-NMR and 13C-NMR) and 2D-NMR (H-H COSY and H-C HMBC) spectroscopy. All N and O carbonyl atoms are involved in hydrogen bonding, with an average HˑˑˑO distance of 1.89(2) Å and N-HˑˑˑO angles in the range 169.5(2)-177.2(2)°. In the crystal packing the molecules are associated by two strong intermolecular N-H-O hydrogen bonds forming centrosymmetric ring with graph-set motif R²2(8), which are linked by N-HˑˑˑO hydrogen bonds.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.58 n.3 20132013-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072013000300004en10.4067/S0717-97072013000300004 |
| institution |
Scielo Chile |
| collection |
Scielo Chile |
| language |
English |
| description |
In this work, 6-nitroquinazoline-2,4(1H,3H)-dione was obtained in two step with good yields using a facile synthetic method. Its structure was characterized by X-ray single crystal diffraction technique (XRD), IR, 1D-NMR (¹H-NMR and 13C-NMR) and 2D-NMR (H-H COSY and H-C HMBC) spectroscopy. All N and O carbonyl atoms are involved in hydrogen bonding, with an average HˑˑˑO distance of 1.89(2) Å and N-HˑˑˑO angles in the range 169.5(2)-177.2(2)°. In the crystal packing the molecules are associated by two strong intermolecular N-H-O hydrogen bonds forming centrosymmetric ring with graph-set motif R²2(8), which are linked by N-HˑˑˑO hydrogen bonds. |
| author |
KESTERNICH,VÍCTOR PÉREZ-FEHRMANN,MARCIA ORTÍZ,SERGIO VERDUGO,FELIPE BRITO,IVÁN BOLTE,MICHAEL CÁRDENAS,ALEJANDRO |
| spellingShingle |
KESTERNICH,VÍCTOR PÉREZ-FEHRMANN,MARCIA ORTÍZ,SERGIO VERDUGO,FELIPE BRITO,IVÁN BOLTE,MICHAEL CÁRDENAS,ALEJANDRO SYNTHESIS, SPECTROSCOPIC CHARACTERIZATION AND X-RAY ANALYSIS OF 6-NITROQUINAZOLINE-2,4(1H,3H)-DIONE |
| author_facet |
KESTERNICH,VÍCTOR PÉREZ-FEHRMANN,MARCIA ORTÍZ,SERGIO VERDUGO,FELIPE BRITO,IVÁN BOLTE,MICHAEL CÁRDENAS,ALEJANDRO |
| author_sort |
KESTERNICH,VÍCTOR |
| title |
SYNTHESIS, SPECTROSCOPIC CHARACTERIZATION AND X-RAY ANALYSIS OF 6-NITROQUINAZOLINE-2,4(1H,3H)-DIONE |
| title_short |
SYNTHESIS, SPECTROSCOPIC CHARACTERIZATION AND X-RAY ANALYSIS OF 6-NITROQUINAZOLINE-2,4(1H,3H)-DIONE |
| title_full |
SYNTHESIS, SPECTROSCOPIC CHARACTERIZATION AND X-RAY ANALYSIS OF 6-NITROQUINAZOLINE-2,4(1H,3H)-DIONE |
| title_fullStr |
SYNTHESIS, SPECTROSCOPIC CHARACTERIZATION AND X-RAY ANALYSIS OF 6-NITROQUINAZOLINE-2,4(1H,3H)-DIONE |
| title_full_unstemmed |
SYNTHESIS, SPECTROSCOPIC CHARACTERIZATION AND X-RAY ANALYSIS OF 6-NITROQUINAZOLINE-2,4(1H,3H)-DIONE |
| title_sort |
synthesis, spectroscopic characterization and x-ray analysis of 6-nitroquinazoline-2,4(1h,3h)-dione |
| publisher |
Sociedad Chilena de Química |
| publishDate |
2013 |
| url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072013000300004 |
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