A COMPARATIVE STUDY OF THERMODYNAMIC PROPERTIES OF STRUCTURALLY RELATED PHENOTHIAZINE DRUGS IN AQUEOUS SOLUTION

Association characteristics of amphiphilic phenothiazine drugs Fluphenazine and Trifluperazine dihydrochloride in water have been examined and their thermodynamic parameters have been calculated using conductometry. The electrical conductivity was measured as a function of concentration at various t...

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Autores principales: USMAN,MUHAMMAD, CHEEMA,MUHAMMAD ARIF, KHAN,ABBAS, FAROOQI,ZAHOOR HUSSAIN, MOSQUERA,VICTOR, SIDDIQ,MOHAMMAD
Lenguaje:English
Publicado: Sociedad Chilena de Química 2013
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072013000300010
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spelling oai:scielo:S0717-970720130003000102014-09-09A COMPARATIVE STUDY OF THERMODYNAMIC PROPERTIES OF STRUCTURALLY RELATED PHENOTHIAZINE DRUGS IN AQUEOUS SOLUTIONUSMAN,MUHAMMADCHEEMA,MUHAMMAD ARIFKHAN,ABBASFAROOQI,ZAHOOR HUSSAINMOSQUERA,VICTORSIDDIQ,MOHAMMADAssociation characteristics of amphiphilic phenothiazine drugs Fluphenazine and Trifluperazine dihydrochloride in water have been examined and their thermodynamic parameters have been calculated using conductometry. The electrical conductivity was measured as a function of concentration at various temperatures and cmc was calculated in the temperature range of 20-50°C. Thermodynamic parameters i.e. standard free energy of micellization, ΔG° , standard enthalpy of micellization, ΔH°m and standard entropy of micellization, ASm were calculated from cmc value using closed association model.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.58 n.3 20132013-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072013000300010en10.4067/S0717-97072013000300010
institution Scielo Chile
collection Scielo Chile
language English
description Association characteristics of amphiphilic phenothiazine drugs Fluphenazine and Trifluperazine dihydrochloride in water have been examined and their thermodynamic parameters have been calculated using conductometry. The electrical conductivity was measured as a function of concentration at various temperatures and cmc was calculated in the temperature range of 20-50°C. Thermodynamic parameters i.e. standard free energy of micellization, ΔG° , standard enthalpy of micellization, ΔH°m and standard entropy of micellization, ASm were calculated from cmc value using closed association model.
author USMAN,MUHAMMAD
CHEEMA,MUHAMMAD ARIF
KHAN,ABBAS
FAROOQI,ZAHOOR HUSSAIN
MOSQUERA,VICTOR
SIDDIQ,MOHAMMAD
spellingShingle USMAN,MUHAMMAD
CHEEMA,MUHAMMAD ARIF
KHAN,ABBAS
FAROOQI,ZAHOOR HUSSAIN
MOSQUERA,VICTOR
SIDDIQ,MOHAMMAD
A COMPARATIVE STUDY OF THERMODYNAMIC PROPERTIES OF STRUCTURALLY RELATED PHENOTHIAZINE DRUGS IN AQUEOUS SOLUTION
author_facet USMAN,MUHAMMAD
CHEEMA,MUHAMMAD ARIF
KHAN,ABBAS
FAROOQI,ZAHOOR HUSSAIN
MOSQUERA,VICTOR
SIDDIQ,MOHAMMAD
author_sort USMAN,MUHAMMAD
title A COMPARATIVE STUDY OF THERMODYNAMIC PROPERTIES OF STRUCTURALLY RELATED PHENOTHIAZINE DRUGS IN AQUEOUS SOLUTION
title_short A COMPARATIVE STUDY OF THERMODYNAMIC PROPERTIES OF STRUCTURALLY RELATED PHENOTHIAZINE DRUGS IN AQUEOUS SOLUTION
title_full A COMPARATIVE STUDY OF THERMODYNAMIC PROPERTIES OF STRUCTURALLY RELATED PHENOTHIAZINE DRUGS IN AQUEOUS SOLUTION
title_fullStr A COMPARATIVE STUDY OF THERMODYNAMIC PROPERTIES OF STRUCTURALLY RELATED PHENOTHIAZINE DRUGS IN AQUEOUS SOLUTION
title_full_unstemmed A COMPARATIVE STUDY OF THERMODYNAMIC PROPERTIES OF STRUCTURALLY RELATED PHENOTHIAZINE DRUGS IN AQUEOUS SOLUTION
title_sort comparative study of thermodynamic properties of structurally related phenothiazine drugs in aqueous solution
publisher Sociedad Chilena de Química
publishDate 2013
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072013000300010
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