SYNTHESIS, STRUCTURAL CHARACTERIZATION AND ENZYME INHIBITION STUDIES ON 5-(2-NITROSTYRYL)-1,3,4-OXADIAZOLE-2-THIOL DERIVATIVES

SYNTHESIS, STRUCTURAL CHARACTERIZATION AND ENZYME INHIBITION STUDIES ON 5-(2-NITROSTYRYL)-1,3,4-OXADIAZOLE-2-THIOL DERIVATIVES

In the present work, S-substituted derivatives of 5-(2-nitrostyryl)-1,3,4-oxadiazole-2-thiol (4) were synthesized by successive conversions of 3-(2-nitrophenyl) acrylic acid (1) into its respective ester, hydrazide and 1,3,4-oxadiazole. Finally the target compounds were obtained by reaction of 5-(2-...

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Main Authors: ABBASI,MUHAMMAD ATHAR, AKHTAR,ADNAN, AZIZ-UR-REHMAN, NAFEESA,KHADIJA, SIDDIQUI,SABAHAT ZAHRA, KHAN,KHALID MOHAMMED, ASHRAF,MUHAMMAD, EJAZ,SYEDA ABIDA
Language:English
Published: Sociedad Chilena de Química 2013
Subjects:
3-(2-nitrophenyl)acrylic acid
5-(2-nitrostyryl)-1,3,4-oxadiazole-2-thiol
¹H-NMR
EI-MS
enzymatic activities
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072013000400061
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