FREE RADICAL SCAVENGING, IMMUNOMODULATORY ACTIVITY AND CHEMICAL COMPOSITION OF LUFFA ACUTANGULA VAR: AMARA (CUCURBITACEAE) PERICARP

The Luffa acutangula Var. amara (Cucurbitaceae) is climbing shrub; commonly known as wild ridge gourd. Its aerial parts are used traditionally in diverse health ailments. Four successive extracts of L. amara pericarp (LAP) were evaluated for antioxidant using in vitro for DPPH, ABTS, superoxides rad...

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Autores principales:	MOHAN G.,KALASKAR, SANJAY J.,SURANA
Lenguaje:	English
Publicado:	Sociedad Chilena de Química 2014
Materias:	Luffa acutangula var. amara pericarp antioxidant immunomodulator
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072014000100012
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spelling	oai:scielo:S0717-970720140001000122015-11-12FREE RADICAL SCAVENGING, IMMUNOMODULATORY ACTIVITY AND CHEMICAL COMPOSITION OF LUFFA ACUTANGULA VAR: AMARA (CUCURBITACEAE) PERICARPMOHAN G.,KALASKARSANJAY J.,SURANA Luffa acutangula var. amara pericarp antioxidant immunomodulator The Luffa acutangula Var. amara (Cucurbitaceae) is climbing shrub; commonly known as wild ridge gourd. Its aerial parts are used traditionally in diverse health ailments. Four successive extracts of L. amara pericarp (LAP) were evaluated for antioxidant using in vitro for DPPH, ABTS, superoxides radical, reducing power and phosphomolybdenum assay. The bioactive ethanol extract was evaluated for immunomodulatory activity by in vivo phagocytosis using carbon clearance and neutrophil adhesion test. The bioactive ethanolic extracts showed potent in vitro antioxidant ability, increased phagocytic index (0.028 ± 0.002), and increased the % neutrophil adhesion (24.63 ± 0.87%). Furthermore, the potent plant phenolics such as gallic acid and p-hydroxybenzoic acid were isolated and identified spectroscopically. The presence of these plant phenolics and like constituents would be responsible for their potent antioxidant and immunomodulatory activity.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.59 n.1 20142014-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072014000100012en10.4067/S0717-97072014000100012
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Luffa acutangula var. amara pericarp antioxidant immunomodulator
spellingShingle	Luffa acutangula var. amara pericarp antioxidant immunomodulator MOHAN G.,KALASKAR SANJAY J.,SURANA FREE RADICAL SCAVENGING, IMMUNOMODULATORY ACTIVITY AND CHEMICAL COMPOSITION OF LUFFA ACUTANGULA VAR: AMARA (CUCURBITACEAE) PERICARP
description	The Luffa acutangula Var. amara (Cucurbitaceae) is climbing shrub; commonly known as wild ridge gourd. Its aerial parts are used traditionally in diverse health ailments. Four successive extracts of L. amara pericarp (LAP) were evaluated for antioxidant using in vitro for DPPH, ABTS, superoxides radical, reducing power and phosphomolybdenum assay. The bioactive ethanol extract was evaluated for immunomodulatory activity by in vivo phagocytosis using carbon clearance and neutrophil adhesion test. The bioactive ethanolic extracts showed potent in vitro antioxidant ability, increased phagocytic index (0.028 ± 0.002), and increased the % neutrophil adhesion (24.63 ± 0.87%). Furthermore, the potent plant phenolics such as gallic acid and p-hydroxybenzoic acid were isolated and identified spectroscopically. The presence of these plant phenolics and like constituents would be responsible for their potent antioxidant and immunomodulatory activity.
author	MOHAN G.,KALASKAR SANJAY J.,SURANA
author_facet	MOHAN G.,KALASKAR SANJAY J.,SURANA
author_sort	MOHAN G.,KALASKAR
title	FREE RADICAL SCAVENGING, IMMUNOMODULATORY ACTIVITY AND CHEMICAL COMPOSITION OF LUFFA ACUTANGULA VAR: AMARA (CUCURBITACEAE) PERICARP
title_short	FREE RADICAL SCAVENGING, IMMUNOMODULATORY ACTIVITY AND CHEMICAL COMPOSITION OF LUFFA ACUTANGULA VAR: AMARA (CUCURBITACEAE) PERICARP
title_full	FREE RADICAL SCAVENGING, IMMUNOMODULATORY ACTIVITY AND CHEMICAL COMPOSITION OF LUFFA ACUTANGULA VAR: AMARA (CUCURBITACEAE) PERICARP
title_fullStr	FREE RADICAL SCAVENGING, IMMUNOMODULATORY ACTIVITY AND CHEMICAL COMPOSITION OF LUFFA ACUTANGULA VAR: AMARA (CUCURBITACEAE) PERICARP
title_full_unstemmed	FREE RADICAL SCAVENGING, IMMUNOMODULATORY ACTIVITY AND CHEMICAL COMPOSITION OF LUFFA ACUTANGULA VAR: AMARA (CUCURBITACEAE) PERICARP
title_sort	free radical scavenging, immunomodulatory activity and chemical composition of luffa acutangula var: amara (cucurbitaceae) pericarp
publisher	Sociedad Chilena de Química
publishDate	2014
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072014000100012
work_keys_str_mv	AT mohangkalaskar freeradicalscavengingimmunomodulatoryactivityandchemicalcompositionofluffaacutangulavaramaracucurbitaceaepericarp AT sanjayjsurana freeradicalscavengingimmunomodulatoryactivityandchemicalcompositionofluffaacutangulavaramaracucurbitaceaepericarp
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FREE RADICAL SCAVENGING, IMMUNOMODULATORY ACTIVITY AND CHEMICAL COMPOSITION OF LUFFA ACUTANGULA VAR: AMARA (CUCURBITACEAE) PERICARP

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