A CONVENIENT SYNTHESIS AND CYTOTOXIC ACTIVITY OF 3-ARYL-5-PENTYL-1,2,4-OXADIAZOLES FROM CARBOXYLIC ACID ESTERS AND ARYLAMIDOXIMES UNDER SOLVENT-FREE CONDITIONS

A CONVENIENT SYNTHESIS AND CYTOTOXIC ACTIVITY OF 3-ARYL-5-PENTYL-1,2,4-OXADIAZOLES FROM CARBOXYLIC ACID ESTERS AND ARYLAMIDOXIMES UNDER SOLVENT-FREE CONDITIONS

The synthesis of 3-aryl-5-pentyl-1,2,4-oxadiazoles from carboxylic acid esters and arylamidoximes in the presence of potassium carbonate is described. The reaction was carried out in a microwave oven without any solvent in much shorter time and in good yields. The structures of the synthesized compo...

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Autores principales: PIMENTEL BARROS,CARLOS JONNATAN, CARDOSO DE SOUZA,ZILYANE, RUFINO DE FREITAS,JUCLEITON JOSÉ, NORBERTO DA SILVA,PAULO BRUNO, GADELHA MILITÃO,GARDENIA CARMEN, GONÇALVES DA SILVA,TERESINHA, RUFINO FREITAS,JULIANO CARLO, RUFINO DE FREITAS FILHO,JOÃO
Lenguaje:English
Publicado: Sociedad Chilena de Química 2014
Materias:
1,2,4-Oxadiazoles
Amidoximes
Microwave oven
Cytotoxic Activity
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072014000100024
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