SOTALOL CHIRAL SEPARATION BY CAPILLARY ELECTROPHORESIS

Differences between the pharmaceutical activity among the enantiomers of sotalol are well known, as R-sotalol and S-sotalol have similar antiarrythmic activities but only the R-enantiomer exhibits β-blocking activity. In this study capillary zone electrophoresis was used for the enantiomeri...

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Autores principales: HANCU,GABRIEL, SĂMĂRGHIŢAN,CLAUDIA, RUSU,AURA, MIRCIA,ELEONORA
Lenguaje:English
Publicado: Sociedad Chilena de Química 2014
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072014000300007
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