STUDIES ON THE ALKYLATION OF QUINOLIN-2(1H)-ONE DERIVATIVES

STUDIES ON THE ALKYLATION OF QUINOLIN-2(1H)-ONE DERIVATIVES

Alkylation of quinolin-2(1H)-one (1) and its C(6) and C(7) substituted dervatives (OMe, OBn, and Cl) with 2-bromoacetophenone or chloroacetone under basic condition (K2CO3 in DMF) gave a mixture of N1- and O2- alkylated products with the former one as a major product. However, alkylation of 8-methox...

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Bibliographic Details
Main Authors: CHEN,CHIA-LING, CHEN,I-LI, CHEN,JIH-JUNG, WEI,DAU-CHANG, HSIEH,HAN-JIE, CHANG,KEN-MING, TZENG,CHERNG-CHYI, WANG,TAI-CHI
Language:English
Published: Sociedad Chilena de Química 2015
Subjects:
N-Alkylation
O-Alkylation
Quinolin-2(1H)-one
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072015000100008
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