A SINGLE HPLC-DAD METHOD FOR SIMULTANEOUS ANALYSIS OF PARACETAMOL, PHENYLEPHRINE, CAFFEINE AND LEVOCETIRIZINE IN BULK POWDER AND TABLET FORMULATION: APPLICATION TO IN-VITRO DISSOLUTION STUDIES

A SINGLE HPLC-DAD METHOD FOR SIMULTANEOUS ANALYSIS OF PARACETAMOL, PHENYLEPHRINE, CAFFEINE AND LEVOCETIRIZINE IN BULK POWDER AND TABLET FORMULATION: APPLICATION TO IN-VITRO DISSOLUTION STUDIES

Present work describes development and validation of HPLC-DAD method for the analysis of a complex mixture consisting phenylephrine hydrochloride (PHE), paracetamol (PAR), caffeine (CAF) and levocetirizine (LEV). Chromatographic separation was achieved using a Kinetex-C18 column involving gradient e...

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Bibliographic Details
Main Authors: DEWANI,ANIL P, PATRA,SRDHANJALI
Language:English
Published: Sociedad Chilena de Química 2015
Subjects:
phenylephrine
paracetamol
caffeine
levocetirizine
HPLC-DAD
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072015000400019
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