SYNTHESIS AND ANTIMICROBIAL EVALUATION OF SOME NEW ASYMMETRICALLY SUBSTITUTED 4-ARYL- 2,6-DI(COUMARINYL) PYRIDINES

In the present work the synthesis of various 4-aryl-2-(coumarin-3-yl)-6-(4-methyl-3-phenyl coumarin-6-yl)pyridines (6a-i) and 4-aryl-2-(coumarin-3-yl)-6-(4-methyl-7-methoxy coumarin-8-yl)pyridines (7a-i) have been carried out by reacting 1-[2(H)-1-benzopyran-3-yl]-3-aryl-prop-2-en-1-ones (coumarinoy...

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Autores principales:	CHOVATIYA,YOGITA L, KUNDALIYA,KAUSHIK N, GIRI,RAKESH R, BRAHMBHATT,DINKER I
Lenguaje:	English
Publicado:	Sociedad Chilena de Química 2016
Materias:	Keywords: Dicoumarinyl pyridines Krohnke's reaction antimicrobial activity Broth dilution method
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072016000100009
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spelling	oai:scielo:S0717-970720160001000092016-09-14SYNTHESIS AND ANTIMICROBIAL EVALUATION OF SOME NEW ASYMMETRICALLY SUBSTITUTED 4-ARYL- 2,6-DI(COUMARINYL) PYRIDINESCHOVATIYA,YOGITA LKUNDALIYA,KAUSHIK NGIRI,RAKESH RBRAHMBHATT,DINKER I Keywords: Dicoumarinyl pyridines Krohnke's reaction antimicrobial activity Broth dilution method In the present work the synthesis of various 4-aryl-2-(coumarin-3-yl)-6-(4-methyl-3-phenyl coumarin-6-yl)pyridines (6a-i) and 4-aryl-2-(coumarin-3-yl)-6-(4-methyl-7-methoxy coumarin-8-yl)pyridines (7a-i) have been carried out by reacting 1-[2(H)-1-benzopyran-3-yl]-3-aryl-prop-2-en-1-ones (coumarinoyl chalcones) (3a-f) with appropriate coumarinoyl methyl pyridinium bromide salt 4 and 5 respectively. The target compounds were characterized by the IR,J H-NMR, 13C-APT and mass spectral analysis. Preliminary examination of target compounds as antimicrobial agents has been carried out using Broth dilutionmethod.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.61 n.1 20162016-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072016000100009en10.4067/S0717-97072016000100009
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Keywords: Dicoumarinyl pyridines Krohnke's reaction antimicrobial activity Broth dilution method
spellingShingle	Keywords: Dicoumarinyl pyridines Krohnke's reaction antimicrobial activity Broth dilution method CHOVATIYA,YOGITA L KUNDALIYA,KAUSHIK N GIRI,RAKESH R BRAHMBHATT,DINKER I SYNTHESIS AND ANTIMICROBIAL EVALUATION OF SOME NEW ASYMMETRICALLY SUBSTITUTED 4-ARYL- 2,6-DI(COUMARINYL) PYRIDINES
description	In the present work the synthesis of various 4-aryl-2-(coumarin-3-yl)-6-(4-methyl-3-phenyl coumarin-6-yl)pyridines (6a-i) and 4-aryl-2-(coumarin-3-yl)-6-(4-methyl-7-methoxy coumarin-8-yl)pyridines (7a-i) have been carried out by reacting 1-[2(H)-1-benzopyran-3-yl]-3-aryl-prop-2-en-1-ones (coumarinoyl chalcones) (3a-f) with appropriate coumarinoyl methyl pyridinium bromide salt 4 and 5 respectively. The target compounds were characterized by the IR,J H-NMR, 13C-APT and mass spectral analysis. Preliminary examination of target compounds as antimicrobial agents has been carried out using Broth dilutionmethod.
author	CHOVATIYA,YOGITA L KUNDALIYA,KAUSHIK N GIRI,RAKESH R BRAHMBHATT,DINKER I
author_facet	CHOVATIYA,YOGITA L KUNDALIYA,KAUSHIK N GIRI,RAKESH R BRAHMBHATT,DINKER I
author_sort	CHOVATIYA,YOGITA L
title	SYNTHESIS AND ANTIMICROBIAL EVALUATION OF SOME NEW ASYMMETRICALLY SUBSTITUTED 4-ARYL- 2,6-DI(COUMARINYL) PYRIDINES
title_short	SYNTHESIS AND ANTIMICROBIAL EVALUATION OF SOME NEW ASYMMETRICALLY SUBSTITUTED 4-ARYL- 2,6-DI(COUMARINYL) PYRIDINES
title_full	SYNTHESIS AND ANTIMICROBIAL EVALUATION OF SOME NEW ASYMMETRICALLY SUBSTITUTED 4-ARYL- 2,6-DI(COUMARINYL) PYRIDINES
title_fullStr	SYNTHESIS AND ANTIMICROBIAL EVALUATION OF SOME NEW ASYMMETRICALLY SUBSTITUTED 4-ARYL- 2,6-DI(COUMARINYL) PYRIDINES
title_full_unstemmed	SYNTHESIS AND ANTIMICROBIAL EVALUATION OF SOME NEW ASYMMETRICALLY SUBSTITUTED 4-ARYL- 2,6-DI(COUMARINYL) PYRIDINES
title_sort	synthesis and antimicrobial evaluation of some new asymmetrically substituted 4-aryl- 2,6-di(coumarinyl) pyridines
publisher	Sociedad Chilena de Química
publishDate	2016
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072016000100009
work_keys_str_mv	AT chovatiyayogital synthesisandantimicrobialevaluationofsomenewasymmetricallysubstituted4aryl26dicoumarinylpyridines AT kundaliyakaushikn synthesisandantimicrobialevaluationofsomenewasymmetricallysubstituted4aryl26dicoumarinylpyridines AT girirakeshr synthesisandantimicrobialevaluationofsomenewasymmetricallysubstituted4aryl26dicoumarinylpyridines AT brahmbhattdinkeri synthesisandantimicrobialevaluationofsomenewasymmetricallysubstituted4aryl26dicoumarinylpyridines
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SYNTHESIS AND ANTIMICROBIAL EVALUATION OF SOME NEW ASYMMETRICALLY SUBSTITUTED 4-ARYL- 2,6-DI(COUMARINYL) PYRIDINES

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