TEMPERATURE EFFECT ON BINDING AFFINITY AND STOICHIOMETRY BETWEEN SOME STEROIDS AND HUMAN SERUM ALBUMIN

The temperature dependence of the interactions between some steroids (fusidic acid, ouabain and ethynodioldiacetate) and human serum albumin (HSA) at physiological pH (7.4) were studied systematically by square-wave voltammetry. Also, these interactions were proven by means of UV-Vis. absorptionspec...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	ÖZDEMÍR,SERKAN, BÍÇER,ENDER
Lenguaje:	English
Publicado:	Sociedad Chilena de Química 2016
Materias:	steroids human serum albumin binding affinity temperature effect voltammetry
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072016000100013
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0717-97072016000100013
record_format	dspace
spelling	oai:scielo:S0717-970720160001000132016-09-14TEMPERATURE EFFECT ON BINDING AFFINITY AND STOICHIOMETRY BETWEEN SOME STEROIDS AND HUMAN SERUM ALBUMINÖZDEMÍR,SERKANBÍÇER,ENDER steroids human serum albumin binding affinity temperature effect voltammetry The temperature dependence of the interactions between some steroids (fusidic acid, ouabain and ethynodioldiacetate) and human serum albumin (HSA) at physiological pH (7.4) were studied systematically by square-wave voltammetry. Also, these interactions were proven by means of UV-Vis. absorptionspectroscopy and FT-IR spectroscopy techniques. The interaction parameters (binding constants and stoichiometries) at temperature range of 297.5-312.5 K weredetermined from electrochemical data. It is worthy that the temperature has played a positive role on the interactions of fusidic acid with HSA; however it hasnegative effective on the interaction parameters of HSA with ouabain or ethynodioldiacetate.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.61 n.1 20162016-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072016000100013en10.4067/S0717-97072016000100013
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	steroids human serum albumin binding affinity temperature effect voltammetry
spellingShingle	steroids human serum albumin binding affinity temperature effect voltammetry ÖZDEMÍR,SERKAN BÍÇER,ENDER TEMPERATURE EFFECT ON BINDING AFFINITY AND STOICHIOMETRY BETWEEN SOME STEROIDS AND HUMAN SERUM ALBUMIN
description	The temperature dependence of the interactions between some steroids (fusidic acid, ouabain and ethynodioldiacetate) and human serum albumin (HSA) at physiological pH (7.4) were studied systematically by square-wave voltammetry. Also, these interactions were proven by means of UV-Vis. absorptionspectroscopy and FT-IR spectroscopy techniques. The interaction parameters (binding constants and stoichiometries) at temperature range of 297.5-312.5 K weredetermined from electrochemical data. It is worthy that the temperature has played a positive role on the interactions of fusidic acid with HSA; however it hasnegative effective on the interaction parameters of HSA with ouabain or ethynodioldiacetate.
author	ÖZDEMÍR,SERKAN BÍÇER,ENDER
author_facet	ÖZDEMÍR,SERKAN BÍÇER,ENDER
author_sort	ÖZDEMÍR,SERKAN
title	TEMPERATURE EFFECT ON BINDING AFFINITY AND STOICHIOMETRY BETWEEN SOME STEROIDS AND HUMAN SERUM ALBUMIN
title_short	TEMPERATURE EFFECT ON BINDING AFFINITY AND STOICHIOMETRY BETWEEN SOME STEROIDS AND HUMAN SERUM ALBUMIN
title_full	TEMPERATURE EFFECT ON BINDING AFFINITY AND STOICHIOMETRY BETWEEN SOME STEROIDS AND HUMAN SERUM ALBUMIN
title_fullStr	TEMPERATURE EFFECT ON BINDING AFFINITY AND STOICHIOMETRY BETWEEN SOME STEROIDS AND HUMAN SERUM ALBUMIN
title_full_unstemmed	TEMPERATURE EFFECT ON BINDING AFFINITY AND STOICHIOMETRY BETWEEN SOME STEROIDS AND HUMAN SERUM ALBUMIN
title_sort	temperature effect on binding affinity and stoichiometry between some steroids and human serum albumin
publisher	Sociedad Chilena de Química
publishDate	2016
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072016000100013
work_keys_str_mv	AT ozdemirserkan temperatureeffectonbindingaffinityandstoichiometrybetweensomesteroidsandhumanserumalbumin AT bicerender temperatureeffectonbindingaffinityandstoichiometrybetweensomesteroidsandhumanserumalbumin
_version_	1718445547986092032

TEMPERATURE EFFECT ON BINDING AFFINITY AND STOICHIOMETRY BETWEEN SOME STEROIDS AND HUMAN SERUM ALBUMIN

Ejemplares similares