DESIGN, SYNTHESIS AND ANTIMICROBIAL ACTIVITIES OF 1-(4-OXO-3-(4-FLUOROPHENYL)-3H-QUINAZOLIN- 2-YL)-4-(SUBSTITUTED) THIOSEMICARBAZIDE DERIVATIVES

DESIGN, SYNTHESIS AND ANTIMICROBIAL ACTIVITIES OF 1-(4-OXO-3-(4-FLUOROPHENYL)-3H-QUINAZOLIN- 2-YL)-4-(SUBSTITUTED) THIOSEMICARBAZIDE DERIVATIVES

A new series of 1-(4-oxo-3-(4-fluorophenyl)-3H-quinazolin-2-yl)-4-(substituted) thiosemicarbazides (AR1-AR10) were obtained by the reaction of 2-hydrazino-3-(4-fluorophenyl) quinazolin-4(3H/)-one (6) with different dithiocarbamic acid methyl ester derivatives. The key intermediate 3-(4-fluorophenyl)...

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Bibliographic Details
Main Authors: ALAGARSAMY,V, APPANI,RAMGOPAL, SULTHANA,M. T, NARENDAR,B, SOLOMON,V. RAJA
Language:English
Published: Sociedad Chilena de Química 2016
Subjects:
Quinazolinone
Substituted thiosemicarbazide
Anti-bacterial
Antitubercular activity
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072016000200002
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http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072016000200002

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