ISOLATION STUDIES FROM STEM EXTRACT OF PISTACIA INTEGERRIMA STEW. EX BRAND

Plants have been source of fantastic natural compounds that range in complexity. Chemical studies on traditional medicinal plants have led to discovery of potent bioactive components. Pistacia integerrima belonging to family Anacardiaceae has been traditionally effective for rheumatic pain, analgesi...

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Autores principales: BIBI,YAMIN, QAYYUM,ABDUL, NISA,SOBIA, WAHEED,ABDUL, CHAUDHARY,MUHAMMAD FAYYAZ
Lenguaje:English
Publicado: Sociedad Chilena de Química 2016
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072016000200014
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spelling oai:scielo:S0717-970720160002000142016-09-14ISOLATION STUDIES FROM STEM EXTRACT OF PISTACIA INTEGERRIMA STEW. EX BRANDBIBI,YAMINQAYYUM,ABDULNISA,SOBIAWAHEED,ABDULCHAUDHARY,MUHAMMAD FAYYAZ Pistacia integerrima Analgesic Extract Ethyl acetate fraction Column chromatography Nucleic magnetic resonance Plants have been source of fantastic natural compounds that range in complexity. Chemical studies on traditional medicinal plants have led to discovery of potent bioactive components. Pistacia integerrima belonging to family Anacardiaceae has been traditionally effective for rheumatic pain, analgesic and antipyretic effects and used in treatment of coughs, phthisis, asthma and dysentery. Natural products have served as basis for compounds to be utilized in drug discovery. Stem extract of Pistacia integerrima was investigated with the aim to find some novel components that can later be used as drugs or active pharmaceutical intermediates. Plant material was collected from Margalla Hills Islamabad, shade dried and subjected to cold maceration technique for extraction. Crude extract was partitioned into different fractions on polarity basis. Repeated normal and reverse phase column chromatography of ethyl acetate fraction supported by Thin Layer Chromatography have led to the isolation of pure single compound. Isolated compound was further analyzed towards structural elucidation using LC-MS, IR and NMR spectroscopy. Present finding will be a useful and novel addition in already known chemical components from Pistacia integerrima.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.61 n.2 20162016-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072016000200014en10.4067/S0717-97072016000200014
institution Scielo Chile
collection Scielo Chile
language English
topic Pistacia integerrima
Analgesic
Extract
Ethyl acetate fraction
Column chromatography
Nucleic magnetic resonance
spellingShingle Pistacia integerrima
Analgesic
Extract
Ethyl acetate fraction
Column chromatography
Nucleic magnetic resonance
BIBI,YAMIN
QAYYUM,ABDUL
NISA,SOBIA
WAHEED,ABDUL
CHAUDHARY,MUHAMMAD FAYYAZ
ISOLATION STUDIES FROM STEM EXTRACT OF PISTACIA INTEGERRIMA STEW. EX BRAND
description Plants have been source of fantastic natural compounds that range in complexity. Chemical studies on traditional medicinal plants have led to discovery of potent bioactive components. Pistacia integerrima belonging to family Anacardiaceae has been traditionally effective for rheumatic pain, analgesic and antipyretic effects and used in treatment of coughs, phthisis, asthma and dysentery. Natural products have served as basis for compounds to be utilized in drug discovery. Stem extract of Pistacia integerrima was investigated with the aim to find some novel components that can later be used as drugs or active pharmaceutical intermediates. Plant material was collected from Margalla Hills Islamabad, shade dried and subjected to cold maceration technique for extraction. Crude extract was partitioned into different fractions on polarity basis. Repeated normal and reverse phase column chromatography of ethyl acetate fraction supported by Thin Layer Chromatography have led to the isolation of pure single compound. Isolated compound was further analyzed towards structural elucidation using LC-MS, IR and NMR spectroscopy. Present finding will be a useful and novel addition in already known chemical components from Pistacia integerrima.
author BIBI,YAMIN
QAYYUM,ABDUL
NISA,SOBIA
WAHEED,ABDUL
CHAUDHARY,MUHAMMAD FAYYAZ
author_facet BIBI,YAMIN
QAYYUM,ABDUL
NISA,SOBIA
WAHEED,ABDUL
CHAUDHARY,MUHAMMAD FAYYAZ
author_sort BIBI,YAMIN
title ISOLATION STUDIES FROM STEM EXTRACT OF PISTACIA INTEGERRIMA STEW. EX BRAND
title_short ISOLATION STUDIES FROM STEM EXTRACT OF PISTACIA INTEGERRIMA STEW. EX BRAND
title_full ISOLATION STUDIES FROM STEM EXTRACT OF PISTACIA INTEGERRIMA STEW. EX BRAND
title_fullStr ISOLATION STUDIES FROM STEM EXTRACT OF PISTACIA INTEGERRIMA STEW. EX BRAND
title_full_unstemmed ISOLATION STUDIES FROM STEM EXTRACT OF PISTACIA INTEGERRIMA STEW. EX BRAND
title_sort isolation studies from stem extract of pistacia integerrima stew. ex brand
publisher Sociedad Chilena de Química
publishDate 2016
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072016000200014
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