SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL PROPERTIES OF NEW CODEINE FE(III) COMPLEX

The reaction of FeCl3 hexahydrate with C18H20NO3.PO4 in acetonitrile produced new complex with general formula [Fe(L)]Cl2, (L= codeine). Characterization of the ligand and its complex were made by elemental analysis, FT-IR, ¹H-NMR, Raman and UV-visible spectroscopy. This new complex showed antitumor...

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Autores principales:	GHAMAMI,SHAHRIAR, GOLZANI,MOJDEH, LASHGARI,AMIR
Lenguaje:	English
Publicado:	Sociedad Chilena de Química 2016
Materias:	Codeine Fe(III) complex Synthesis Anti-tumor AGS and MCF-7 Antibacterial
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072016000200020
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spelling	oai:scielo:S0717-970720160002000202016-09-14SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL PROPERTIES OF NEW CODEINE FE(III) COMPLEXGHAMAMI,SHAHRIARGOLZANI,MOJDEHLASHGARI,AMIR Codeine Fe(III) complex Synthesis Anti-tumor AGS and MCF-7 Antibacterial The reaction of FeCl3 hexahydrate with C18H20NO3.PO4 in acetonitrile produced new complex with general formula [Fe(L)]Cl2, (L= codeine). Characterization of the ligand and its complex were made by elemental analysis, FT-IR, ¹H-NMR, Raman and UV-visible spectroscopy. This new complex showed antitumor activity against two kinds of cancer cell lines: AGS (Stomach) and MCF-7 (Breast). Cell cytotoxic effects of the ligand and its complex were assayed by MTT and Natural-red tests. The antibacterial activity of ligand and complex against Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus pyogenes and Escherichia coli were also examined.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.61 n.2 20162016-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072016000200020en10.4067/S0717-97072016000200020
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Codeine Fe(III) complex Synthesis Anti-tumor AGS and MCF-7 Antibacterial
spellingShingle	Codeine Fe(III) complex Synthesis Anti-tumor AGS and MCF-7 Antibacterial GHAMAMI,SHAHRIAR GOLZANI,MOJDEH LASHGARI,AMIR SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL PROPERTIES OF NEW CODEINE FE(III) COMPLEX
description	The reaction of FeCl3 hexahydrate with C18H20NO3.PO4 in acetonitrile produced new complex with general formula [Fe(L)]Cl2, (L= codeine). Characterization of the ligand and its complex were made by elemental analysis, FT-IR, ¹H-NMR, Raman and UV-visible spectroscopy. This new complex showed antitumor activity against two kinds of cancer cell lines: AGS (Stomach) and MCF-7 (Breast). Cell cytotoxic effects of the ligand and its complex were assayed by MTT and Natural-red tests. The antibacterial activity of ligand and complex against Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus pyogenes and Escherichia coli were also examined.
author	GHAMAMI,SHAHRIAR GOLZANI,MOJDEH LASHGARI,AMIR
author_facet	GHAMAMI,SHAHRIAR GOLZANI,MOJDEH LASHGARI,AMIR
author_sort	GHAMAMI,SHAHRIAR
title	SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL PROPERTIES OF NEW CODEINE FE(III) COMPLEX
title_short	SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL PROPERTIES OF NEW CODEINE FE(III) COMPLEX
title_full	SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL PROPERTIES OF NEW CODEINE FE(III) COMPLEX
title_fullStr	SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL PROPERTIES OF NEW CODEINE FE(III) COMPLEX
title_full_unstemmed	SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL PROPERTIES OF NEW CODEINE FE(III) COMPLEX
title_sort	synthesis, characterization and biological properties of new codeine fe(iii) complex
publisher	Sociedad Chilena de Química
publishDate	2016
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072016000200020
work_keys_str_mv	AT ghamamishahriar synthesischaracterizationandbiologicalpropertiesofnewcodeinefeiiicomplex AT golzanimojdeh synthesischaracterizationandbiologicalpropertiesofnewcodeinefeiiicomplex AT lashgariamir synthesischaracterizationandbiologicalpropertiesofnewcodeinefeiiicomplex
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SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL PROPERTIES OF NEW CODEINE FE(III) COMPLEX

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