THE EFFECT OF DIFFERENT RETINA DISEASES ON CHOLESTEROL AND FATTY ACID CONTENT OF SILICONE OIL FROM VITRECTOMIZED EYES

The differences of cholesterol and fatty acid content of silicone oils that were removed from vitrectomized eyes due to different retinal diseases were investigated. The silicone oils were removed from 25 cases after 4-8 months and classified in two groups; Group A consists of 11 patients who had un...

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Autores principales:	GÜNGEL,HULYA, TEKKELI,SERIFE EVRIM KEPEKCI
Lenguaje:	English
Publicado:	Sociedad Chilena de Química 2016
Materias:	fatty acids FTIR silicone epoxigenases
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072016000200027
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spelling	oai:scielo:S0717-970720160002000272016-09-14THE EFFECT OF DIFFERENT RETINA DISEASES ON CHOLESTEROL AND FATTY ACID CONTENT OF SILICONE OIL FROM VITRECTOMIZED EYESGÜNGEL,HULYATEKKELI,SERIFE EVRIM KEPEKCI fatty acids FTIR silicone epoxigenases The differences of cholesterol and fatty acid content of silicone oils that were removed from vitrectomized eyes due to different retinal diseases were investigated. The silicone oils were removed from 25 cases after 4-8 months and classified in two groups; Group A consists of 11 patients who had undergone pars plana vitrectomy combined with phacoemulsification and intraocular lens implantation due to diabetic tractional retinal detachment and Group B consists of 14 patients who was treated for phakic primary rhegmatogenous retinal detachment. The removed material from vitrectomized eyes in Group A was opacified and gelatinous on the other hand in Group B it was transparent. Hexan extracts were prepared from liquid and emulsified phases. The extracts were taken into vials, after that, hexane was removed. The chemical structure of each extracted material was investigated by spectroscopic techniques. The concentration of unsaturated fatty acids (FAs) in both groups were compared statistically. In conclusion, in Group A, epoxy and hydroxy-epoxy FAs were determined. The mean amount of unsaturated FAs in Group A was significantly lower than Group B. Cholesterol was not detected in any samples. The type of FAs in removed silicone oils may differ depending on the oxidative stress of retina.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.61 n.2 20162016-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072016000200027en10.4067/S0717-97072016000200027
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	fatty acids FTIR silicone epoxigenases
spellingShingle	fatty acids FTIR silicone epoxigenases GÜNGEL,HULYA TEKKELI,SERIFE EVRIM KEPEKCI THE EFFECT OF DIFFERENT RETINA DISEASES ON CHOLESTEROL AND FATTY ACID CONTENT OF SILICONE OIL FROM VITRECTOMIZED EYES
description	The differences of cholesterol and fatty acid content of silicone oils that were removed from vitrectomized eyes due to different retinal diseases were investigated. The silicone oils were removed from 25 cases after 4-8 months and classified in two groups; Group A consists of 11 patients who had undergone pars plana vitrectomy combined with phacoemulsification and intraocular lens implantation due to diabetic tractional retinal detachment and Group B consists of 14 patients who was treated for phakic primary rhegmatogenous retinal detachment. The removed material from vitrectomized eyes in Group A was opacified and gelatinous on the other hand in Group B it was transparent. Hexan extracts were prepared from liquid and emulsified phases. The extracts were taken into vials, after that, hexane was removed. The chemical structure of each extracted material was investigated by spectroscopic techniques. The concentration of unsaturated fatty acids (FAs) in both groups were compared statistically. In conclusion, in Group A, epoxy and hydroxy-epoxy FAs were determined. The mean amount of unsaturated FAs in Group A was significantly lower than Group B. Cholesterol was not detected in any samples. The type of FAs in removed silicone oils may differ depending on the oxidative stress of retina.
author	GÜNGEL,HULYA TEKKELI,SERIFE EVRIM KEPEKCI
author_facet	GÜNGEL,HULYA TEKKELI,SERIFE EVRIM KEPEKCI
author_sort	GÜNGEL,HULYA
title	THE EFFECT OF DIFFERENT RETINA DISEASES ON CHOLESTEROL AND FATTY ACID CONTENT OF SILICONE OIL FROM VITRECTOMIZED EYES
title_short	THE EFFECT OF DIFFERENT RETINA DISEASES ON CHOLESTEROL AND FATTY ACID CONTENT OF SILICONE OIL FROM VITRECTOMIZED EYES
title_full	THE EFFECT OF DIFFERENT RETINA DISEASES ON CHOLESTEROL AND FATTY ACID CONTENT OF SILICONE OIL FROM VITRECTOMIZED EYES
title_fullStr	THE EFFECT OF DIFFERENT RETINA DISEASES ON CHOLESTEROL AND FATTY ACID CONTENT OF SILICONE OIL FROM VITRECTOMIZED EYES
title_full_unstemmed	THE EFFECT OF DIFFERENT RETINA DISEASES ON CHOLESTEROL AND FATTY ACID CONTENT OF SILICONE OIL FROM VITRECTOMIZED EYES
title_sort	effect of different retina diseases on cholesterol and fatty acid content of silicone oil from vitrectomized eyes
publisher	Sociedad Chilena de Química
publishDate	2016
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072016000200027
work_keys_str_mv	AT gungelhulya theeffectofdifferentretinadiseasesoncholesterolandfattyacidcontentofsiliconeoilfromvitrectomizedeyes AT tekkeliserifeevrimkepekci theeffectofdifferentretinadiseasesoncholesterolandfattyacidcontentofsiliconeoilfromvitrectomizedeyes AT gungelhulya effectofdifferentretinadiseasesoncholesterolandfattyacidcontentofsiliconeoilfromvitrectomizedeyes AT tekkeliserifeevrimkepekci effectofdifferentretinadiseasesoncholesterolandfattyacidcontentofsiliconeoilfromvitrectomizedeyes
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THE EFFECT OF DIFFERENT RETINA DISEASES ON CHOLESTEROL AND FATTY ACID CONTENT OF SILICONE OIL FROM VITRECTOMIZED EYES

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