LAÇASSE CATALYZED-SYNTHESIS OF 4,4'-BIPHENYLDIAMINE FROM P-CHLOROANILINE. EVALUATION OF ANTIFUNGAL AND ANTIOXIDANT ACTIVITIES

Laccase is a copper-containing oxidase that catalyzes reduction of molecular oxygen to water and the oxidation of a phenolic compound. In this paper, laccase was utilized to synthesize 4,4'-Biphenyldiamine using p-chloroaniline as substrate by means of a coupling reaction. The synthesized compo...

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Autores principales: CAMPOS,ANA M, MENDOZA,LEONORA, VASQUEZ,JUAN, MELO,RICARDO, SALAS,JENNIFER, COTORAS,MILENA
Lenguaje:English
Publicado: Sociedad Chilena de Química 2016
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072016000300004
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Sumario:Laccase is a copper-containing oxidase that catalyzes reduction of molecular oxygen to water and the oxidation of a phenolic compound. In this paper, laccase was utilized to synthesize 4,4'-Biphenyldiamine using p-chloroaniline as substrate by means of a coupling reaction. The synthesized compound, 4,4'-Biphenyldiamine, presented low antifungal activity against the phytopathogenic fungus Botrytis cinerea, however the antioxidant ability, measurement by ORAC-PGR method, was higher than substrate. This work corresponds to the first report of synthesis 4,4'-Biphenyldiamine, from p-chloroaniline in a lacasse-catalyzed reaction.