PHYTOCHEMICAL ANALYSIS OF ALKALOIDS FROM THE CHILEAN ENDEMIC TREE CRYPTOCARYA ALBA

A phytochemical study of the roots and aerial parts of Cryptocarya alba (Mol.) Looser (Lauraceae), an endemic Chilean tree and the southernmost Cryptocarya species, led for the first time to the isolation and unambiguous characterization of four known alkaloids by NMR techniques: boldine, laurolitsi...

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Autores principales: CASTRO-SAAVEDRA,SEBASTIÁN, FUENTES-BARROS,GONZALO, TIRAPEGUI,CRISTIAN, ACEVEDO-FUENTES,WILLIAMS, CASSELS,BRUCE K, BARRIGA,ANDRÉS, VILCHES-HERRERA,MARCELO
Lenguaje:English
Publicado: Sociedad Chilena de Química 2016
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072016000300014
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spelling oai:scielo:S0717-970720160003000142017-06-14PHYTOCHEMICAL ANALYSIS OF ALKALOIDS FROM THE CHILEAN ENDEMIC TREE CRYPTOCARYA ALBACASTRO-SAAVEDRA,SEBASTIÁNFUENTES-BARROS,GONZALOTIRAPEGUI,CRISTIANACEVEDO-FUENTES,WILLIAMSCASSELS,BRUCE KBARRIGA,ANDRÉSVILCHES-HERRERA,MARCELOA phytochemical study of the roots and aerial parts of Cryptocarya alba (Mol.) Looser (Lauraceae), an endemic Chilean tree and the southernmost Cryptocarya species, led for the first time to the isolation and unambiguous characterization of four known alkaloids by NMR techniques: boldine, laurolitsine, laurotetanine and norglaucine, in addition to the previously identified reticuline, and the identification via UHPLC-MS of seven more alkaloids, coclaurine, N-methylcoclaurine, norreticuline, isocorydine, N-methyllaurotetanine, predicentrine and glaucine. In spite of this fairly broad variety of benzyltetrahydroisoquinolines and aporphines, the concentrations of these alkaloids in the different organs of C. alba are quite low, which is in contrast with the sometimes generous yields of alkaloids in this genus.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.61 n.3 20162016-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072016000300014en10.4067/S0717-97072016000300014
institution Scielo Chile
collection Scielo Chile
language English
description A phytochemical study of the roots and aerial parts of Cryptocarya alba (Mol.) Looser (Lauraceae), an endemic Chilean tree and the southernmost Cryptocarya species, led for the first time to the isolation and unambiguous characterization of four known alkaloids by NMR techniques: boldine, laurolitsine, laurotetanine and norglaucine, in addition to the previously identified reticuline, and the identification via UHPLC-MS of seven more alkaloids, coclaurine, N-methylcoclaurine, norreticuline, isocorydine, N-methyllaurotetanine, predicentrine and glaucine. In spite of this fairly broad variety of benzyltetrahydroisoquinolines and aporphines, the concentrations of these alkaloids in the different organs of C. alba are quite low, which is in contrast with the sometimes generous yields of alkaloids in this genus.
author CASTRO-SAAVEDRA,SEBASTIÁN
FUENTES-BARROS,GONZALO
TIRAPEGUI,CRISTIAN
ACEVEDO-FUENTES,WILLIAMS
CASSELS,BRUCE K
BARRIGA,ANDRÉS
VILCHES-HERRERA,MARCELO
spellingShingle CASTRO-SAAVEDRA,SEBASTIÁN
FUENTES-BARROS,GONZALO
TIRAPEGUI,CRISTIAN
ACEVEDO-FUENTES,WILLIAMS
CASSELS,BRUCE K
BARRIGA,ANDRÉS
VILCHES-HERRERA,MARCELO
PHYTOCHEMICAL ANALYSIS OF ALKALOIDS FROM THE CHILEAN ENDEMIC TREE CRYPTOCARYA ALBA
author_facet CASTRO-SAAVEDRA,SEBASTIÁN
FUENTES-BARROS,GONZALO
TIRAPEGUI,CRISTIAN
ACEVEDO-FUENTES,WILLIAMS
CASSELS,BRUCE K
BARRIGA,ANDRÉS
VILCHES-HERRERA,MARCELO
author_sort CASTRO-SAAVEDRA,SEBASTIÁN
title PHYTOCHEMICAL ANALYSIS OF ALKALOIDS FROM THE CHILEAN ENDEMIC TREE CRYPTOCARYA ALBA
title_short PHYTOCHEMICAL ANALYSIS OF ALKALOIDS FROM THE CHILEAN ENDEMIC TREE CRYPTOCARYA ALBA
title_full PHYTOCHEMICAL ANALYSIS OF ALKALOIDS FROM THE CHILEAN ENDEMIC TREE CRYPTOCARYA ALBA
title_fullStr PHYTOCHEMICAL ANALYSIS OF ALKALOIDS FROM THE CHILEAN ENDEMIC TREE CRYPTOCARYA ALBA
title_full_unstemmed PHYTOCHEMICAL ANALYSIS OF ALKALOIDS FROM THE CHILEAN ENDEMIC TREE CRYPTOCARYA ALBA
title_sort phytochemical analysis of alkaloids from the chilean endemic tree cryptocarya alba
publisher Sociedad Chilena de Química
publishDate 2016
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072016000300014
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