BENZAMIDE DERIVATIVES AS POTENTIAL CANDIDATES FOR ANTI-ALZHEIMER, ANTI-FATIGUE, ANTI-UREASE AND ANTI-OXIDANT ACTIVITY
Benzamide derivatives were screened for their anti-alzheimer, anti-fatigue, anti-urease and anti-oxidant activity and their results were calculated in the form of %age inhibition and IC50 value. Compounds 3a and 3g exhibited the highest anti alzheimer activity. Group of mice's treated by compou...
Guardado en:
| Autores principales: | , , , , , |
|---|---|
| Lenguaje: | English |
| Publicado: |
Sociedad Chilena de Química
2017
|
| Acceso en línea: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072017000100007 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:scielo:S0717-97072017000100007 |
|---|---|
| record_format |
dspace |
| spelling |
oai:scielo:S0717-970720170001000072017-05-05BENZAMIDE DERIVATIVES AS POTENTIAL CANDIDATES FOR ANTI-ALZHEIMER, ANTI-FATIGUE, ANTI-UREASE AND ANTI-OXIDANT ACTIVITYTAJ,M. BTIRMIZI,S. ARAHEEL,AALI,H. B. MQURESHI,SALSHATIR,HBenzamide derivatives were screened for their anti-alzheimer, anti-fatigue, anti-urease and anti-oxidant activity and their results were calculated in the form of %age inhibition and IC50 value. Compounds 3a and 3g exhibited the highest anti alzheimer activity. Group of mice's treated by compounds 3f and 3g showed significantly longer swimming times than those of the treated with caffeine. The prominent urease inhibitory activity was shown by only one compound among seven benzamide derivatives. Controlled experiments suggest that benzamide derivatives (3a-3g) can be serve as the therapeutic agentsinfo:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.62 n.1 20172017-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072017000100007en10.4067/S0717-97072017000100007 |
| institution |
Scielo Chile |
| collection |
Scielo Chile |
| language |
English |
| description |
Benzamide derivatives were screened for their anti-alzheimer, anti-fatigue, anti-urease and anti-oxidant activity and their results were calculated in the form of %age inhibition and IC50 value. Compounds 3a and 3g exhibited the highest anti alzheimer activity. Group of mice's treated by compounds 3f and 3g showed significantly longer swimming times than those of the treated with caffeine. The prominent urease inhibitory activity was shown by only one compound among seven benzamide derivatives. Controlled experiments suggest that benzamide derivatives (3a-3g) can be serve as the therapeutic agents |
| author |
TAJ,M. B TIRMIZI,S. A RAHEEL,A ALI,H. B. M QURESHI,S ALSHATIR,H |
| spellingShingle |
TAJ,M. B TIRMIZI,S. A RAHEEL,A ALI,H. B. M QURESHI,S ALSHATIR,H BENZAMIDE DERIVATIVES AS POTENTIAL CANDIDATES FOR ANTI-ALZHEIMER, ANTI-FATIGUE, ANTI-UREASE AND ANTI-OXIDANT ACTIVITY |
| author_facet |
TAJ,M. B TIRMIZI,S. A RAHEEL,A ALI,H. B. M QURESHI,S ALSHATIR,H |
| author_sort |
TAJ,M. B |
| title |
BENZAMIDE DERIVATIVES AS POTENTIAL CANDIDATES FOR ANTI-ALZHEIMER, ANTI-FATIGUE, ANTI-UREASE AND ANTI-OXIDANT ACTIVITY |
| title_short |
BENZAMIDE DERIVATIVES AS POTENTIAL CANDIDATES FOR ANTI-ALZHEIMER, ANTI-FATIGUE, ANTI-UREASE AND ANTI-OXIDANT ACTIVITY |
| title_full |
BENZAMIDE DERIVATIVES AS POTENTIAL CANDIDATES FOR ANTI-ALZHEIMER, ANTI-FATIGUE, ANTI-UREASE AND ANTI-OXIDANT ACTIVITY |
| title_fullStr |
BENZAMIDE DERIVATIVES AS POTENTIAL CANDIDATES FOR ANTI-ALZHEIMER, ANTI-FATIGUE, ANTI-UREASE AND ANTI-OXIDANT ACTIVITY |
| title_full_unstemmed |
BENZAMIDE DERIVATIVES AS POTENTIAL CANDIDATES FOR ANTI-ALZHEIMER, ANTI-FATIGUE, ANTI-UREASE AND ANTI-OXIDANT ACTIVITY |
| title_sort |
benzamide derivatives as potential candidates for anti-alzheimer, anti-fatigue, anti-urease and anti-oxidant activity |
| publisher |
Sociedad Chilena de Química |
| publishDate |
2017 |
| url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072017000100007 |
| work_keys_str_mv |
AT tajmb benzamidederivativesaspotentialcandidatesforantialzheimerantifatigueantiureaseandantioxidantactivity AT tirmizisa benzamidederivativesaspotentialcandidatesforantialzheimerantifatigueantiureaseandantioxidantactivity AT raheela benzamidederivativesaspotentialcandidatesforantialzheimerantifatigueantiureaseandantioxidantactivity AT alihbm benzamidederivativesaspotentialcandidatesforantialzheimerantifatigueantiureaseandantioxidantactivity AT qureshis benzamidederivativesaspotentialcandidatesforantialzheimerantifatigueantiureaseandantioxidantactivity AT alshatirh benzamidederivativesaspotentialcandidatesforantialzheimerantifatigueantiureaseandantioxidantactivity |
| _version_ |
1714200906040344576 |