SYNTHESIS OF TETRASUBSTITUTD IMIDAZOLES CONTAINING INDOLE AND THEIR ANTIUREASE AND ANTIOXIDANT ACTIVITIES

ABSTRACT Indole-based tetraarylimidazoles were prepared by multicomponent reaction of substituted 2-arylindole-3-carbaldehydes, benzil, substituted anilines and ammonium acetate in acetic acid. The new compounds were evaluated for their antiurease and antioxidant activity. The synthesized compounds...

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Autores principales: NAUREEN,SADIA, IJAZ,FATIMA, MUNAWAR,MUNAWAR ALI, ASIF,NADIA, CHAUDHRY,FARYAL, ASHRAF,MUHAMMAD, KHAN,MISBAHUL AIN
Lenguaje:English
Publicado: Sociedad Chilena de Química 2017
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072017000303583
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spelling oai:scielo:S0717-970720170003035832017-09-08SYNTHESIS OF TETRASUBSTITUTD IMIDAZOLES CONTAINING INDOLE AND THEIR ANTIUREASE AND ANTIOXIDANT ACTIVITIESNAUREEN,SADIAIJAZ,FATIMAMUNAWAR,MUNAWAR ALIASIF,NADIACHAUDHRY,FARYALASHRAF,MUHAMMADKHAN,MISBAHUL AIN Imidazole Indole antitumor ammonium acetate ABSTRACT Indole-based tetraarylimidazoles were prepared by multicomponent reaction of substituted 2-arylindole-3-carbaldehydes, benzil, substituted anilines and ammonium acetate in acetic acid. The new compounds were evaluated for their antiurease and antioxidant activity. The synthesized compounds exhibited potent antiurease activity.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.62 n.3 20172017-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072017000303583en10.4067/s0717-97072017000303583
institution Scielo Chile
collection Scielo Chile
language English
topic Imidazole
Indole
antitumor
ammonium acetate
spellingShingle Imidazole
Indole
antitumor
ammonium acetate
NAUREEN,SADIA
IJAZ,FATIMA
MUNAWAR,MUNAWAR ALI
ASIF,NADIA
CHAUDHRY,FARYAL
ASHRAF,MUHAMMAD
KHAN,MISBAHUL AIN
SYNTHESIS OF TETRASUBSTITUTD IMIDAZOLES CONTAINING INDOLE AND THEIR ANTIUREASE AND ANTIOXIDANT ACTIVITIES
description ABSTRACT Indole-based tetraarylimidazoles were prepared by multicomponent reaction of substituted 2-arylindole-3-carbaldehydes, benzil, substituted anilines and ammonium acetate in acetic acid. The new compounds were evaluated for their antiurease and antioxidant activity. The synthesized compounds exhibited potent antiurease activity.
author NAUREEN,SADIA
IJAZ,FATIMA
MUNAWAR,MUNAWAR ALI
ASIF,NADIA
CHAUDHRY,FARYAL
ASHRAF,MUHAMMAD
KHAN,MISBAHUL AIN
author_facet NAUREEN,SADIA
IJAZ,FATIMA
MUNAWAR,MUNAWAR ALI
ASIF,NADIA
CHAUDHRY,FARYAL
ASHRAF,MUHAMMAD
KHAN,MISBAHUL AIN
author_sort NAUREEN,SADIA
title SYNTHESIS OF TETRASUBSTITUTD IMIDAZOLES CONTAINING INDOLE AND THEIR ANTIUREASE AND ANTIOXIDANT ACTIVITIES
title_short SYNTHESIS OF TETRASUBSTITUTD IMIDAZOLES CONTAINING INDOLE AND THEIR ANTIUREASE AND ANTIOXIDANT ACTIVITIES
title_full SYNTHESIS OF TETRASUBSTITUTD IMIDAZOLES CONTAINING INDOLE AND THEIR ANTIUREASE AND ANTIOXIDANT ACTIVITIES
title_fullStr SYNTHESIS OF TETRASUBSTITUTD IMIDAZOLES CONTAINING INDOLE AND THEIR ANTIUREASE AND ANTIOXIDANT ACTIVITIES
title_full_unstemmed SYNTHESIS OF TETRASUBSTITUTD IMIDAZOLES CONTAINING INDOLE AND THEIR ANTIUREASE AND ANTIOXIDANT ACTIVITIES
title_sort synthesis of tetrasubstitutd imidazoles containing indole and their antiurease and antioxidant activities
publisher Sociedad Chilena de Química
publishDate 2017
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072017000303583
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AT munawarmunawarali synthesisoftetrasubstitutdimidazolescontainingindoleandtheirantiureaseandantioxidantactivities
AT asifnadia synthesisoftetrasubstitutdimidazolescontainingindoleandtheirantiureaseandantioxidantactivities
AT chaudhryfaryal synthesisoftetrasubstitutdimidazolescontainingindoleandtheirantiureaseandantioxidantactivities
AT ashrafmuhammad synthesisoftetrasubstitutdimidazolescontainingindoleandtheirantiureaseandantioxidantactivities
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