SECONDARY METABOLITES FROM PACHYSTROMA LONGIFOLIUM (NEES) I. M. JOHNST (EUPHORBIACEAE) AND EVALUATION OF ITS EXTRACTS AS CATHEPSINS INHIBITORS

SECONDARY METABOLITES FROM PACHYSTROMA LONGIFOLIUM (NEES) I. M. JOHNST (EUPHORBIACEAE) AND EVALUATION OF ITS EXTRACTS AS CATHEPSINS INHIBITORS

ABSTRACT In this work, four secondary metabolites were isolated from leaves of Pachystroma longifolium (Euphorbiaceae): loliolide, gallic acid, methyl protocatechuate and ethyl gallate. Their structures were established by physical and spectroscopic methods. The extracts of P. longifolium and the pu...

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Autores principales: GALVÃO,DAYANE DE CÁSSIA, TORRES MORAES,CAROLINA, PINHEIRO BORGES,BÁRBARA JULIANA, CAVALCANTE CARDOSO,WEVERSON, ANDRADE,JEAN PAULO DE, MITSUO TAKAHASHI,PEDRO, VIEIRA,PAULO CEZAR, BORGES,WARLEY DE SOUZA
Lenguaje:English
Publicado: Sociedad Chilena de Química 2017
Materias:
Pachystroma longifolium
secondary metabolites
cathepsins
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072017000303602
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Sumario:ABSTRACT In this work, four secondary metabolites were isolated from leaves of Pachystroma longifolium (Euphorbiaceae): loliolide, gallic acid, methyl protocatechuate and ethyl gallate. Their structures were established by physical and spectroscopic methods. The extracts of P. longifolium and the purified compounds were tested as cathepsins inhibitors and the extracts were active.

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