SECONDARY METABOLITES FROM PACHYSTROMA LONGIFOLIUM (NEES) I. M. JOHNST (EUPHORBIACEAE) AND EVALUATION OF ITS EXTRACTS AS CATHEPSINS INHIBITORS

ABSTRACT In this work, four secondary metabolites were isolated from leaves of Pachystroma longifolium (Euphorbiaceae): loliolide, gallic acid, methyl protocatechuate and ethyl gallate. Their structures were established by physical and spectroscopic methods. The extracts of P. longifolium and the pu...

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Autores principales: GALVÃO,DAYANE DE CÁSSIA, TORRES MORAES,CAROLINA, PINHEIRO BORGES,BÁRBARA JULIANA, CAVALCANTE CARDOSO,WEVERSON, ANDRADE,JEAN PAULO DE, MITSUO TAKAHASHI,PEDRO, VIEIRA,PAULO CEZAR, BORGES,WARLEY DE SOUZA
Lenguaje:English
Publicado: Sociedad Chilena de Química 2017
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072017000303602
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spelling oai:scielo:S0717-970720170003036022017-09-08SECONDARY METABOLITES FROM PACHYSTROMA LONGIFOLIUM (NEES) I. M. JOHNST (EUPHORBIACEAE) AND EVALUATION OF ITS EXTRACTS AS CATHEPSINS INHIBITORSGALVÃO,DAYANE DE CÁSSIATORRES MORAES,CAROLINAPINHEIRO BORGES,BÁRBARA JULIANACAVALCANTE CARDOSO,WEVERSONANDRADE,JEAN PAULO DEMITSUO TAKAHASHI,PEDROVIEIRA,PAULO CEZARBORGES,WARLEY DE SOUZA Pachystroma longifolium secondary metabolites cathepsins ABSTRACT In this work, four secondary metabolites were isolated from leaves of Pachystroma longifolium (Euphorbiaceae): loliolide, gallic acid, methyl protocatechuate and ethyl gallate. Their structures were established by physical and spectroscopic methods. The extracts of P. longifolium and the purified compounds were tested as cathepsins inhibitors and the extracts were active.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.62 n.3 20172017-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072017000303602en10.4067/s0717-97072017000303602
institution Scielo Chile
collection Scielo Chile
language English
topic Pachystroma longifolium
secondary metabolites
cathepsins
spellingShingle Pachystroma longifolium
secondary metabolites
cathepsins
GALVÃO,DAYANE DE CÁSSIA
TORRES MORAES,CAROLINA
PINHEIRO BORGES,BÁRBARA JULIANA
CAVALCANTE CARDOSO,WEVERSON
ANDRADE,JEAN PAULO DE
MITSUO TAKAHASHI,PEDRO
VIEIRA,PAULO CEZAR
BORGES,WARLEY DE SOUZA
SECONDARY METABOLITES FROM PACHYSTROMA LONGIFOLIUM (NEES) I. M. JOHNST (EUPHORBIACEAE) AND EVALUATION OF ITS EXTRACTS AS CATHEPSINS INHIBITORS
description ABSTRACT In this work, four secondary metabolites were isolated from leaves of Pachystroma longifolium (Euphorbiaceae): loliolide, gallic acid, methyl protocatechuate and ethyl gallate. Their structures were established by physical and spectroscopic methods. The extracts of P. longifolium and the purified compounds were tested as cathepsins inhibitors and the extracts were active.
author GALVÃO,DAYANE DE CÁSSIA
TORRES MORAES,CAROLINA
PINHEIRO BORGES,BÁRBARA JULIANA
CAVALCANTE CARDOSO,WEVERSON
ANDRADE,JEAN PAULO DE
MITSUO TAKAHASHI,PEDRO
VIEIRA,PAULO CEZAR
BORGES,WARLEY DE SOUZA
author_facet GALVÃO,DAYANE DE CÁSSIA
TORRES MORAES,CAROLINA
PINHEIRO BORGES,BÁRBARA JULIANA
CAVALCANTE CARDOSO,WEVERSON
ANDRADE,JEAN PAULO DE
MITSUO TAKAHASHI,PEDRO
VIEIRA,PAULO CEZAR
BORGES,WARLEY DE SOUZA
author_sort GALVÃO,DAYANE DE CÁSSIA
title SECONDARY METABOLITES FROM PACHYSTROMA LONGIFOLIUM (NEES) I. M. JOHNST (EUPHORBIACEAE) AND EVALUATION OF ITS EXTRACTS AS CATHEPSINS INHIBITORS
title_short SECONDARY METABOLITES FROM PACHYSTROMA LONGIFOLIUM (NEES) I. M. JOHNST (EUPHORBIACEAE) AND EVALUATION OF ITS EXTRACTS AS CATHEPSINS INHIBITORS
title_full SECONDARY METABOLITES FROM PACHYSTROMA LONGIFOLIUM (NEES) I. M. JOHNST (EUPHORBIACEAE) AND EVALUATION OF ITS EXTRACTS AS CATHEPSINS INHIBITORS
title_fullStr SECONDARY METABOLITES FROM PACHYSTROMA LONGIFOLIUM (NEES) I. M. JOHNST (EUPHORBIACEAE) AND EVALUATION OF ITS EXTRACTS AS CATHEPSINS INHIBITORS
title_full_unstemmed SECONDARY METABOLITES FROM PACHYSTROMA LONGIFOLIUM (NEES) I. M. JOHNST (EUPHORBIACEAE) AND EVALUATION OF ITS EXTRACTS AS CATHEPSINS INHIBITORS
title_sort secondary metabolites from pachystroma longifolium (nees) i. m. johnst (euphorbiaceae) and evaluation of its extracts as cathepsins inhibitors
publisher Sociedad Chilena de Química
publishDate 2017
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072017000303602
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