TRIFLUOROACETIC ACID CATALYZED ONE-POT FOUR-COMPONENT DOMINO REACTION FOR THE SYNTHESIS OF SUBSTITUTED DIHYDRO 2-OXYPYRROLES

ABSTRACT Trifluoroacetic acid was applied as an efficient catalyst for the one-pot four-component synthesis of N-aryl/alkyl-3-aminodihydropyrrol-2-one-4-carboxylates via the domino reaction of amines, formaldehyde and dialkyl acetylenedicarboxylates at ambient temperature in methanol. This methodolo...

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Autores principales:	Lashkari,Mojtaba, Maghsoodlou,Malek Taher, Karima,Mahsa, Kangani,Mehrnoosh
Lenguaje:	English
Publicado:	Sociedad Chilena de Química 2018
Materias:	Trifluoroacetic acid N-aryl/alkyl-3-aminodihydropyrrol-2-one-4-carboxylates ambient temperature
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072018000103799
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spelling	oai:scielo:S0717-970720180001037992018-05-11TRIFLUOROACETIC ACID CATALYZED ONE-POT FOUR-COMPONENT DOMINO REACTION FOR THE SYNTHESIS OF SUBSTITUTED DIHYDRO 2-OXYPYRROLESLashkari,MojtabaMaghsoodlou,Malek TaherKarima,MahsaKangani,Mehrnoosh Trifluoroacetic acid N-aryl/alkyl-3-aminodihydropyrrol-2-one-4-carboxylates ambient temperature ABSTRACT Trifluoroacetic acid was applied as an efficient catalyst for the one-pot four-component synthesis of N-aryl/alkyl-3-aminodihydropyrrol-2-one-4-carboxylates via the domino reaction of amines, formaldehyde and dialkyl acetylenedicarboxylates at ambient temperature in methanol. This methodology includes number of advantages such as: short reaction time, clean work-up, use of inexpensive catalyst, high yields and clean work-up. The work-up of this reaction involves only a filtration and a simple washing step with MeOH, and there is no need for column chromatography.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.63 n.1 20182018-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072018000103799en10.4067/s0717-97072018000103799
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Trifluoroacetic acid N-aryl/alkyl-3-aminodihydropyrrol-2-one-4-carboxylates ambient temperature
spellingShingle	Trifluoroacetic acid N-aryl/alkyl-3-aminodihydropyrrol-2-one-4-carboxylates ambient temperature Lashkari,Mojtaba Maghsoodlou,Malek Taher Karima,Mahsa Kangani,Mehrnoosh TRIFLUOROACETIC ACID CATALYZED ONE-POT FOUR-COMPONENT DOMINO REACTION FOR THE SYNTHESIS OF SUBSTITUTED DIHYDRO 2-OXYPYRROLES
description	ABSTRACT Trifluoroacetic acid was applied as an efficient catalyst for the one-pot four-component synthesis of N-aryl/alkyl-3-aminodihydropyrrol-2-one-4-carboxylates via the domino reaction of amines, formaldehyde and dialkyl acetylenedicarboxylates at ambient temperature in methanol. This methodology includes number of advantages such as: short reaction time, clean work-up, use of inexpensive catalyst, high yields and clean work-up. The work-up of this reaction involves only a filtration and a simple washing step with MeOH, and there is no need for column chromatography.
author	Lashkari,Mojtaba Maghsoodlou,Malek Taher Karima,Mahsa Kangani,Mehrnoosh
author_facet	Lashkari,Mojtaba Maghsoodlou,Malek Taher Karima,Mahsa Kangani,Mehrnoosh
author_sort	Lashkari,Mojtaba
title	TRIFLUOROACETIC ACID CATALYZED ONE-POT FOUR-COMPONENT DOMINO REACTION FOR THE SYNTHESIS OF SUBSTITUTED DIHYDRO 2-OXYPYRROLES
title_short	TRIFLUOROACETIC ACID CATALYZED ONE-POT FOUR-COMPONENT DOMINO REACTION FOR THE SYNTHESIS OF SUBSTITUTED DIHYDRO 2-OXYPYRROLES
title_full	TRIFLUOROACETIC ACID CATALYZED ONE-POT FOUR-COMPONENT DOMINO REACTION FOR THE SYNTHESIS OF SUBSTITUTED DIHYDRO 2-OXYPYRROLES
title_fullStr	TRIFLUOROACETIC ACID CATALYZED ONE-POT FOUR-COMPONENT DOMINO REACTION FOR THE SYNTHESIS OF SUBSTITUTED DIHYDRO 2-OXYPYRROLES
title_full_unstemmed	TRIFLUOROACETIC ACID CATALYZED ONE-POT FOUR-COMPONENT DOMINO REACTION FOR THE SYNTHESIS OF SUBSTITUTED DIHYDRO 2-OXYPYRROLES
title_sort	trifluoroacetic acid catalyzed one-pot four-component domino reaction for the synthesis of substituted dihydro 2-oxypyrroles
publisher	Sociedad Chilena de Química
publishDate	2018
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072018000103799
work_keys_str_mv	AT lashkarimojtaba trifluoroaceticacidcatalyzedonepotfourcomponentdominoreactionforthesynthesisofsubstituteddihydro2oxypyrroles AT maghsoodloumalektaher trifluoroaceticacidcatalyzedonepotfourcomponentdominoreactionforthesynthesisofsubstituteddihydro2oxypyrroles AT karimamahsa trifluoroaceticacidcatalyzedonepotfourcomponentdominoreactionforthesynthesisofsubstituteddihydro2oxypyrroles AT kanganimehrnoosh trifluoroaceticacidcatalyzedonepotfourcomponentdominoreactionforthesynthesisofsubstituteddihydro2oxypyrroles
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TRIFLUOROACETIC ACID CATALYZED ONE-POT FOUR-COMPONENT DOMINO REACTION FOR THE SYNTHESIS OF SUBSTITUTED DIHYDRO 2-OXYPYRROLES

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