DETERMINATION OF CATECHIN AS BIOMARKER IN ENTOCID POLYHERBAL DIGESTIVE SYRUP BY HPLC/DAD

ABSTRACT Entocid syrup is a balanced composition of vigilantly selected and formulated with effective herbs of proven efficacy in intestinal ailments covering the segment of hyper-acidity symptoms. Entocid is scientifically formulated in such a way that it not only neutralizes the acid secretion but...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Sheikh,Zeeshan Ahmed, Siddiqui,Zafar Ali, Naveed,Safila, Usmanghani,Khan
Lenguaje:	English
Publicado:	Sociedad Chilena de Química 2018
Materias:	Polyherbal Entocid Catechin HPLC-DAD Digestive syrup
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072018000203924
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0717-97072018000203924
record_format	dspace
spelling	oai:scielo:S0717-970720180002039242018-07-19DETERMINATION OF CATECHIN AS BIOMARKER IN ENTOCID POLYHERBAL DIGESTIVE SYRUP BY HPLC/DADSheikh,Zeeshan AhmedSiddiqui,Zafar AliNaveed,SafilaUsmanghani,Khan Polyherbal Entocid Catechin HPLC-DAD Digestive syrup ABSTRACT Entocid syrup is a balanced composition of vigilantly selected and formulated with effective herbs of proven efficacy in intestinal ailments covering the segment of hyper-acidity symptoms. Entocid is scientifically formulated in such a way that it not only neutralizes the acid secretion but at the same time it strengthens the stomach thus acts promptly and relieves the symptoms of GI upsets and in the long-run prevents the recurrence of such symptoms. The ingredients of Entocid syrup are rich in alkaloids, proteins, vitamins, glycosides, bioflavonoid and trace elements, formulated using ten potent herbal drugs namely Amomum sabulatum, Berberis aristata, Cinnamomum tamala, Coriandrum sativum, Cuminum cyminum, Foeniculum vulgare, Vitis vinifera, Mesua ferrea, Glycyrrhiza glabra and Mentha piperita. The flavonoid compounds exhibit preventive effects from colon carcinogenesis, lipid lowering effects, anti-oxidant, anti-inflammatory, antidepressant and anti-atherogenic properties. To develop the assay method, high-performance liquid chromatography (HPLC) with a diode-array detector (DAD) was used. Using HPLC/DAD, catechin was eluted with gradient program. The UV characteristic of catechin, the detection wavelength was monitored at 265 nm. Method validation including limit of quantitation, the accuracy, inter and intra day and limitation was performed by using recovery tests. The future development of flavonoids-based drugs is limitation and assumes to provide significant effects on digestion related diseases.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.63 n.2 20182018-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072018000203924en10.4067/s0717-97072018000203924
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Polyherbal Entocid Catechin HPLC-DAD Digestive syrup
spellingShingle	Polyherbal Entocid Catechin HPLC-DAD Digestive syrup Sheikh,Zeeshan Ahmed Siddiqui,Zafar Ali Naveed,Safila Usmanghani,Khan DETERMINATION OF CATECHIN AS BIOMARKER IN ENTOCID POLYHERBAL DIGESTIVE SYRUP BY HPLC/DAD
description	ABSTRACT Entocid syrup is a balanced composition of vigilantly selected and formulated with effective herbs of proven efficacy in intestinal ailments covering the segment of hyper-acidity symptoms. Entocid is scientifically formulated in such a way that it not only neutralizes the acid secretion but at the same time it strengthens the stomach thus acts promptly and relieves the symptoms of GI upsets and in the long-run prevents the recurrence of such symptoms. The ingredients of Entocid syrup are rich in alkaloids, proteins, vitamins, glycosides, bioflavonoid and trace elements, formulated using ten potent herbal drugs namely Amomum sabulatum, Berberis aristata, Cinnamomum tamala, Coriandrum sativum, Cuminum cyminum, Foeniculum vulgare, Vitis vinifera, Mesua ferrea, Glycyrrhiza glabra and Mentha piperita. The flavonoid compounds exhibit preventive effects from colon carcinogenesis, lipid lowering effects, anti-oxidant, anti-inflammatory, antidepressant and anti-atherogenic properties. To develop the assay method, high-performance liquid chromatography (HPLC) with a diode-array detector (DAD) was used. Using HPLC/DAD, catechin was eluted with gradient program. The UV characteristic of catechin, the detection wavelength was monitored at 265 nm. Method validation including limit of quantitation, the accuracy, inter and intra day and limitation was performed by using recovery tests. The future development of flavonoids-based drugs is limitation and assumes to provide significant effects on digestion related diseases.
author	Sheikh,Zeeshan Ahmed Siddiqui,Zafar Ali Naveed,Safila Usmanghani,Khan
author_facet	Sheikh,Zeeshan Ahmed Siddiqui,Zafar Ali Naveed,Safila Usmanghani,Khan
author_sort	Sheikh,Zeeshan Ahmed
title	DETERMINATION OF CATECHIN AS BIOMARKER IN ENTOCID POLYHERBAL DIGESTIVE SYRUP BY HPLC/DAD
title_short	DETERMINATION OF CATECHIN AS BIOMARKER IN ENTOCID POLYHERBAL DIGESTIVE SYRUP BY HPLC/DAD
title_full	DETERMINATION OF CATECHIN AS BIOMARKER IN ENTOCID POLYHERBAL DIGESTIVE SYRUP BY HPLC/DAD
title_fullStr	DETERMINATION OF CATECHIN AS BIOMARKER IN ENTOCID POLYHERBAL DIGESTIVE SYRUP BY HPLC/DAD
title_full_unstemmed	DETERMINATION OF CATECHIN AS BIOMARKER IN ENTOCID POLYHERBAL DIGESTIVE SYRUP BY HPLC/DAD
title_sort	determination of catechin as biomarker in entocid polyherbal digestive syrup by hplc/dad
publisher	Sociedad Chilena de Química
publishDate	2018
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072018000203924
work_keys_str_mv	AT sheikhzeeshanahmed determinationofcatechinasbiomarkerinentocidpolyherbaldigestivesyrupbyhplcdad AT siddiquizafarali determinationofcatechinasbiomarkerinentocidpolyherbaldigestivesyrupbyhplcdad AT naveedsafila determinationofcatechinasbiomarkerinentocidpolyherbaldigestivesyrupbyhplcdad AT usmanghanikhan determinationofcatechinasbiomarkerinentocidpolyherbaldigestivesyrupbyhplcdad
_version_	1714200924050685952

DETERMINATION OF CATECHIN AS BIOMARKER IN ENTOCID POLYHERBAL DIGESTIVE SYRUP BY HPLC/DAD

Ejemplares similares