RECENT APPROACHES FOR THE SYNTHESIS OF HYBRID RESVERATROL MOLECULES AND THEIR BIOLOGICAL ACTIVITIES: A REVIEW

Resveratrol (RSV) is a polyphenol produced by different plant species having a variety of biological activities. Synthesis of hybrid molecules of RSV with different natural and synthetic compounds has been studied. These hybrid molecules have been prepared by using fused or merged techniques or by u...

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Autores principales: Mohsin,Noor Ul Amin, Irfan,Muhammad
Lenguaje:English
Publicado: Sociedad Chilena de Química 2018
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072018000304135
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spelling oai:scielo:S0717-970720180003041352018-10-03RECENT APPROACHES FOR THE SYNTHESIS OF HYBRID RESVERATROL MOLECULES AND THEIR BIOLOGICAL ACTIVITIES: A REVIEWMohsin,Noor Ul AminIrfan,Muhammad Resveratrol (RSV) Wittig reaction aldol condensation natural molecules antitumor activity anti-Alzheimer activity Resveratrol (RSV) is a polyphenol produced by different plant species having a variety of biological activities. Synthesis of hybrid molecules of RSV with different natural and synthetic compounds has been studied. These hybrid molecules have been prepared by using fused or merged techniques or by using some linker groups. Wittig method was mostly applied by using the appropriate ylides to prepare the RSV core. The hybrid molecules prepared by these techniques exhibited anticancer, anti-inflammatory, antioxidant, anti-alzheimer, metal chelating and enzyme inhibitory activities. These hybrid RSV molecules can serve as a lead compounds for the future design of new drug molecules. info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.63 n.3 20182018-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072018000304135en10.4067/s0717-97072018000304135
institution Scielo Chile
collection Scielo Chile
language English
topic Resveratrol (RSV)
Wittig reaction
aldol condensation
natural molecules
antitumor activity
anti-Alzheimer activity
spellingShingle Resveratrol (RSV)
Wittig reaction
aldol condensation
natural molecules
antitumor activity
anti-Alzheimer activity
Mohsin,Noor Ul Amin
Irfan,Muhammad
RECENT APPROACHES FOR THE SYNTHESIS OF HYBRID RESVERATROL MOLECULES AND THEIR BIOLOGICAL ACTIVITIES: A REVIEW
description Resveratrol (RSV) is a polyphenol produced by different plant species having a variety of biological activities. Synthesis of hybrid molecules of RSV with different natural and synthetic compounds has been studied. These hybrid molecules have been prepared by using fused or merged techniques or by using some linker groups. Wittig method was mostly applied by using the appropriate ylides to prepare the RSV core. The hybrid molecules prepared by these techniques exhibited anticancer, anti-inflammatory, antioxidant, anti-alzheimer, metal chelating and enzyme inhibitory activities. These hybrid RSV molecules can serve as a lead compounds for the future design of new drug molecules.
author Mohsin,Noor Ul Amin
Irfan,Muhammad
author_facet Mohsin,Noor Ul Amin
Irfan,Muhammad
author_sort Mohsin,Noor Ul Amin
title RECENT APPROACHES FOR THE SYNTHESIS OF HYBRID RESVERATROL MOLECULES AND THEIR BIOLOGICAL ACTIVITIES: A REVIEW
title_short RECENT APPROACHES FOR THE SYNTHESIS OF HYBRID RESVERATROL MOLECULES AND THEIR BIOLOGICAL ACTIVITIES: A REVIEW
title_full RECENT APPROACHES FOR THE SYNTHESIS OF HYBRID RESVERATROL MOLECULES AND THEIR BIOLOGICAL ACTIVITIES: A REVIEW
title_fullStr RECENT APPROACHES FOR THE SYNTHESIS OF HYBRID RESVERATROL MOLECULES AND THEIR BIOLOGICAL ACTIVITIES: A REVIEW
title_full_unstemmed RECENT APPROACHES FOR THE SYNTHESIS OF HYBRID RESVERATROL MOLECULES AND THEIR BIOLOGICAL ACTIVITIES: A REVIEW
title_sort recent approaches for the synthesis of hybrid resveratrol molecules and their biological activities: a review
publisher Sociedad Chilena de Química
publishDate 2018
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072018000304135
work_keys_str_mv AT mohsinnoorulamin recentapproachesforthesynthesisofhybridresveratrolmoleculesandtheirbiologicalactivitiesareview
AT irfanmuhammad recentapproachesforthesynthesisofhybridresveratrolmoleculesandtheirbiologicalactivitiesareview
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