MAGNETIC SOLID PHASE EXTRACTION APPLICATIONS COMBINED WITH ANALYTICAL METHODS FOR DETERMINATION OF DRUGS IN DIFFERENT MATRICES REVIEW

ABSTRACT Sample preparation procedures are essential for drug analysis in biological fluids, tissues, pharmaceutical preparations, food and environmental matrices. For this purpose different techniques have been used like protein precipitation, liquid liquid extraction (LLE) and solid phase extracti...

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Autores principales:	Kepekci-Tekkeli,Serife Evrim, Durmus,Zehra
Lenguaje:	English
Publicado:	Sociedad Chilena de Química 2019
Materias:	Magnetic solid phase extraction biological fluids drug high performance liquid chromatography review
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072019000204448
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spelling	oai:scielo:S0717-970720190002044482019-10-11MAGNETIC SOLID PHASE EXTRACTION APPLICATIONS COMBINED WITH ANALYTICAL METHODS FOR DETERMINATION OF DRUGS IN DIFFERENT MATRICES REVIEWKepekci-Tekkeli,Serife EvrimDurmus,Zehra Magnetic solid phase extraction biological fluids drug high performance liquid chromatography review ABSTRACT Sample preparation procedures are essential for drug analysis in biological fluids, tissues, pharmaceutical preparations, food and environmental matrices. For this purpose different techniques have been used like protein precipitation, liquid liquid extraction (LLE) and solid phase extraction (SPE). Magnetic solid phase extraction (MSPE) has become a highly preferred method due to its advantages as a sample preparation-pretreatment technique when compared to classical methods as a novel type of SPE. Basically, this type of extraction is based on the separation of different analytes from complex matrices based on the use of magnetic nanoparticles (MNPs) as adsorbents. Magnetic solid phase extraction minimizes the use of additional steps which reduces the manipulation of conventional extractions. The main advantages depend on its simplicity, environmentally friendly process, disposable cost, reduced solvent consumption, and short duration. In this review, special attention is paid on drug analysis by using MSPE prior to various analytical methods from biological, environmental and food matrices. MSPE applications, with various types of magnetic adsorbents, and different analytical method combinations were revealed for drug analysis.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.64 n.2 20192019-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072019000204448en10.4067/S0717-97072019000204448
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Magnetic solid phase extraction biological fluids drug high performance liquid chromatography review
spellingShingle	Magnetic solid phase extraction biological fluids drug high performance liquid chromatography review Kepekci-Tekkeli,Serife Evrim Durmus,Zehra MAGNETIC SOLID PHASE EXTRACTION APPLICATIONS COMBINED WITH ANALYTICAL METHODS FOR DETERMINATION OF DRUGS IN DIFFERENT MATRICES REVIEW
description	ABSTRACT Sample preparation procedures are essential for drug analysis in biological fluids, tissues, pharmaceutical preparations, food and environmental matrices. For this purpose different techniques have been used like protein precipitation, liquid liquid extraction (LLE) and solid phase extraction (SPE). Magnetic solid phase extraction (MSPE) has become a highly preferred method due to its advantages as a sample preparation-pretreatment technique when compared to classical methods as a novel type of SPE. Basically, this type of extraction is based on the separation of different analytes from complex matrices based on the use of magnetic nanoparticles (MNPs) as adsorbents. Magnetic solid phase extraction minimizes the use of additional steps which reduces the manipulation of conventional extractions. The main advantages depend on its simplicity, environmentally friendly process, disposable cost, reduced solvent consumption, and short duration. In this review, special attention is paid on drug analysis by using MSPE prior to various analytical methods from biological, environmental and food matrices. MSPE applications, with various types of magnetic adsorbents, and different analytical method combinations were revealed for drug analysis.
author	Kepekci-Tekkeli,Serife Evrim Durmus,Zehra
author_facet	Kepekci-Tekkeli,Serife Evrim Durmus,Zehra
author_sort	Kepekci-Tekkeli,Serife Evrim
title	MAGNETIC SOLID PHASE EXTRACTION APPLICATIONS COMBINED WITH ANALYTICAL METHODS FOR DETERMINATION OF DRUGS IN DIFFERENT MATRICES REVIEW
title_short	MAGNETIC SOLID PHASE EXTRACTION APPLICATIONS COMBINED WITH ANALYTICAL METHODS FOR DETERMINATION OF DRUGS IN DIFFERENT MATRICES REVIEW
title_full	MAGNETIC SOLID PHASE EXTRACTION APPLICATIONS COMBINED WITH ANALYTICAL METHODS FOR DETERMINATION OF DRUGS IN DIFFERENT MATRICES REVIEW
title_fullStr	MAGNETIC SOLID PHASE EXTRACTION APPLICATIONS COMBINED WITH ANALYTICAL METHODS FOR DETERMINATION OF DRUGS IN DIFFERENT MATRICES REVIEW
title_full_unstemmed	MAGNETIC SOLID PHASE EXTRACTION APPLICATIONS COMBINED WITH ANALYTICAL METHODS FOR DETERMINATION OF DRUGS IN DIFFERENT MATRICES REVIEW
title_sort	magnetic solid phase extraction applications combined with analytical methods for determination of drugs in different matrices review
publisher	Sociedad Chilena de Química
publishDate	2019
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072019000204448
work_keys_str_mv	AT kepekcitekkeliserifeevrim magneticsolidphaseextractionapplicationscombinedwithanalyticalmethodsfordeterminationofdrugsindifferentmatricesreview AT durmuszehra magneticsolidphaseextractionapplicationscombinedwithanalyticalmethodsfordeterminationofdrugsindifferentmatricesreview
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MAGNETIC SOLID PHASE EXTRACTION APPLICATIONS COMBINED WITH ANALYTICAL METHODS FOR DETERMINATION OF DRUGS IN DIFFERENT MATRICES REVIEW

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