A BRIEF REVIEW ON ANALYTICAL METHODS FOR ESTIMATION OF ISRADIPINE IN PHARMACEUTICAL FORMULATION AND BIOLOGICAL MATRICES

ABSTRACT Isradipine (ISRA) is a calcium channel blocking agent and a drug of the dihydropyridine (DHP) class. It is utilized for the treatment of hypertension and congestive cardiac failure (CHF). It selectively binds with the calcium channel receptor with high compatibility and averts calcium alter...

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Autores principales:	Marathe,Sopan R., Patil,Amod S., Ganorkar,Saurabh B., Chaudhari,Suraj, Shirkhedkar,Atul A.
Lenguaje:	English
Publicado:	Sociedad Chilena de Química 2019
Materias:	Isradipine hypertension analytical methods biological samples pharmaceutical formulation
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072019000304565
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spelling	oai:scielo:S0717-970720190003045652019-11-06A BRIEF REVIEW ON ANALYTICAL METHODS FOR ESTIMATION OF ISRADIPINE IN PHARMACEUTICAL FORMULATION AND BIOLOGICAL MATRICESMarathe,Sopan R.Patil,Amod S.Ganorkar,Saurabh B.Chaudhari,SurajShirkhedkar,Atul A. Isradipine hypertension analytical methods biological samples pharmaceutical formulation ABSTRACT Isradipine (ISRA) is a calcium channel blocking agent and a drug of the dihydropyridine (DHP) class. It is utilized for the treatment of hypertension and congestive cardiac failure (CHF). It selectively binds with the calcium channel receptor with high compatibility and averts calcium alteration into cardiac and arterial smooth muscle cells. ISRA employed to cure deliberate hypertension, used alone or in combination with thiazide diuretics. The present review article represents the compilation and discussion of analytical methods published in the literature for estimation of ISRA in pharmaceutical samples and biological matrices consisting of TLC/ densitometry, HPLC, UV-Visible method, Spectrofluorometry, Capillary Electrophoresis (CE), Polarography, Voltammetry and hyphenated techniques such as LC-MS; LC-MS-MS, GC-MS, etc. The anticipated review details about the comparative utilization of various analytical techniques for estimation of ISRA. The present compilation can be essentially explored to potentiate future analytical investigation needs of ISRA.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.64 n.3 20192019-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072019000304565en10.4067/S0717-97072019000304565
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Isradipine hypertension analytical methods biological samples pharmaceutical formulation
spellingShingle	Isradipine hypertension analytical methods biological samples pharmaceutical formulation Marathe,Sopan R. Patil,Amod S. Ganorkar,Saurabh B. Chaudhari,Suraj Shirkhedkar,Atul A. A BRIEF REVIEW ON ANALYTICAL METHODS FOR ESTIMATION OF ISRADIPINE IN PHARMACEUTICAL FORMULATION AND BIOLOGICAL MATRICES
description	ABSTRACT Isradipine (ISRA) is a calcium channel blocking agent and a drug of the dihydropyridine (DHP) class. It is utilized for the treatment of hypertension and congestive cardiac failure (CHF). It selectively binds with the calcium channel receptor with high compatibility and averts calcium alteration into cardiac and arterial smooth muscle cells. ISRA employed to cure deliberate hypertension, used alone or in combination with thiazide diuretics. The present review article represents the compilation and discussion of analytical methods published in the literature for estimation of ISRA in pharmaceutical samples and biological matrices consisting of TLC/ densitometry, HPLC, UV-Visible method, Spectrofluorometry, Capillary Electrophoresis (CE), Polarography, Voltammetry and hyphenated techniques such as LC-MS; LC-MS-MS, GC-MS, etc. The anticipated review details about the comparative utilization of various analytical techniques for estimation of ISRA. The present compilation can be essentially explored to potentiate future analytical investigation needs of ISRA.
author	Marathe,Sopan R. Patil,Amod S. Ganorkar,Saurabh B. Chaudhari,Suraj Shirkhedkar,Atul A.
author_facet	Marathe,Sopan R. Patil,Amod S. Ganorkar,Saurabh B. Chaudhari,Suraj Shirkhedkar,Atul A.
author_sort	Marathe,Sopan R.
title	A BRIEF REVIEW ON ANALYTICAL METHODS FOR ESTIMATION OF ISRADIPINE IN PHARMACEUTICAL FORMULATION AND BIOLOGICAL MATRICES
title_short	A BRIEF REVIEW ON ANALYTICAL METHODS FOR ESTIMATION OF ISRADIPINE IN PHARMACEUTICAL FORMULATION AND BIOLOGICAL MATRICES
title_full	A BRIEF REVIEW ON ANALYTICAL METHODS FOR ESTIMATION OF ISRADIPINE IN PHARMACEUTICAL FORMULATION AND BIOLOGICAL MATRICES
title_fullStr	A BRIEF REVIEW ON ANALYTICAL METHODS FOR ESTIMATION OF ISRADIPINE IN PHARMACEUTICAL FORMULATION AND BIOLOGICAL MATRICES
title_full_unstemmed	A BRIEF REVIEW ON ANALYTICAL METHODS FOR ESTIMATION OF ISRADIPINE IN PHARMACEUTICAL FORMULATION AND BIOLOGICAL MATRICES
title_sort	brief review on analytical methods for estimation of isradipine in pharmaceutical formulation and biological matrices
publisher	Sociedad Chilena de Química
publishDate	2019
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072019000304565
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A BRIEF REVIEW ON ANALYTICAL METHODS FOR ESTIMATION OF ISRADIPINE IN PHARMACEUTICAL FORMULATION AND BIOLOGICAL MATRICES

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