SYNTHESIS OF 6- TERT -OCTYL AND 6,8-DI TERT -BUTYL COUMARINS, TWO COUMARINS OF BIOLOGICAL INTEREST

ABSTRACT In this study, the synthesis of new coumarins with aliphatic chains is discussed. The incorporation of the 6- tert -octyl and 6,8-di tert -butyl chains into a coumarin structure from alkylphenols, allows obtaining hydrophobic coumarins with good yields. These coumarins can be potential modu...

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Main Authors:	Zárraga O.,M., Darouch,M., Lisboa,E., Arroyo P.,P., Miranda M.,A.
Language:	English
Published:	Sociedad Chilena de Química 2021
Subjects:	Coumarins Alkylcoumarins TRPV1
Online Access:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072021000205220
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spelling	oai:scielo:S0717-970720210002052202021-07-05SYNTHESIS OF 6- TERT -OCTYL AND 6,8-DI TERT -BUTYL COUMARINS, TWO COUMARINS OF BIOLOGICAL INTERESTZárraga O.,M.Darouch,M.Lisboa,E.Arroyo P.,P.Miranda M.,A. Coumarins Alkylcoumarins TRPV1 ABSTRACT In this study, the synthesis of new coumarins with aliphatic chains is discussed. The incorporation of the 6- tert -octyl and 6,8-di tert -butyl chains into a coumarin structure from alkylphenols, allows obtaining hydrophobic coumarins with good yields. These coumarins can be potential modulators of TRPV1 receptors. Synthesis and spectroscopic data of these new coumarins are analyzed.info:eu-repo/semantics/openAccessSociedad Chilena de QuímicaJournal of the Chilean Chemical Society v.66 n.2 20212021-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072021000205220en10.4067/S0717-97072021000205220
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Coumarins Alkylcoumarins TRPV1
spellingShingle	Coumarins Alkylcoumarins TRPV1 Zárraga O.,M. Darouch,M. Lisboa,E. Arroyo P.,P. Miranda M.,A. SYNTHESIS OF 6- TERT -OCTYL AND 6,8-DI TERT -BUTYL COUMARINS, TWO COUMARINS OF BIOLOGICAL INTEREST
description	ABSTRACT In this study, the synthesis of new coumarins with aliphatic chains is discussed. The incorporation of the 6- tert -octyl and 6,8-di tert -butyl chains into a coumarin structure from alkylphenols, allows obtaining hydrophobic coumarins with good yields. These coumarins can be potential modulators of TRPV1 receptors. Synthesis and spectroscopic data of these new coumarins are analyzed.
author	Zárraga O.,M. Darouch,M. Lisboa,E. Arroyo P.,P. Miranda M.,A.
author_facet	Zárraga O.,M. Darouch,M. Lisboa,E. Arroyo P.,P. Miranda M.,A.
author_sort	Zárraga O.,M.
title	SYNTHESIS OF 6- TERT -OCTYL AND 6,8-DI TERT -BUTYL COUMARINS, TWO COUMARINS OF BIOLOGICAL INTEREST
title_short	SYNTHESIS OF 6- TERT -OCTYL AND 6,8-DI TERT -BUTYL COUMARINS, TWO COUMARINS OF BIOLOGICAL INTEREST
title_full	SYNTHESIS OF 6- TERT -OCTYL AND 6,8-DI TERT -BUTYL COUMARINS, TWO COUMARINS OF BIOLOGICAL INTEREST
title_fullStr	SYNTHESIS OF 6- TERT -OCTYL AND 6,8-DI TERT -BUTYL COUMARINS, TWO COUMARINS OF BIOLOGICAL INTEREST
title_full_unstemmed	SYNTHESIS OF 6- TERT -OCTYL AND 6,8-DI TERT -BUTYL COUMARINS, TWO COUMARINS OF BIOLOGICAL INTEREST
title_sort	synthesis of 6- tert -octyl and 6,8-di tert -butyl coumarins, two coumarins of biological interest
publisher	Sociedad Chilena de Química
publishDate	2021
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072021000205220
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SYNTHESIS OF 6- TERT -OCTYL AND 6,8-DI TERT -BUTYL COUMARINS, TWO COUMARINS OF BIOLOGICAL INTEREST

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