Bioactive compounds of loquat (Eriobotrya japonica Lindl.) cv. Golden Nugget and analysis of in vitro functionality for hyperglycemia management

Abstract The loquat cultivar Golden Nugget (leaves, flowers and fruits), which has potential commercial importance in Chile, was analyzed for targeted bioactive composition (total phenolic contents: TPC, phenolic profiles and triterpenic acids) and in vitro bioactivity such as antioxidant capacity (...

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Autores principales:	Ahumada,Jaime, Fuentealba,Claudia, Olaeta,José A., Undurraga,Pedro, Pedreschi,Romina, Shetty,Kalidas, Chirinos,Rosana, Campos,David, Ranilla,Lena Gálvez
Lenguaje:	English
Publicado:	Pontificia Universidad Católica de Chile. Facultad de Agronomía e Ingeniería Forestal 2017
Materias:	Eriobotrya japonica phenolic compounds antioxidants anti-hyperglycemia loquat
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-16202017000300272
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spelling	oai:scielo:S0718-162020170003002722018-02-20Bioactive compounds of loquat (Eriobotrya japonica Lindl.) cv. Golden Nugget and analysis of in vitro functionality for hyperglycemia managementAhumada,JaimeFuentealba,ClaudiaOlaeta,José A.Undurraga,PedroPedreschi,RominaShetty,KalidasChirinos,RosanaCampos,DavidRanilla,Lena Gálvez Eriobotrya japonica phenolic compounds antioxidants anti-hyperglycemia loquat Abstract The loquat cultivar Golden Nugget (leaves, flowers and fruits), which has potential commercial importance in Chile, was analyzed for targeted bioactive composition (total phenolic contents: TPC, phenolic profiles and triterpenic acids) and in vitro bioactivity such as antioxidant capacity (AC) and inhibitory activity against enzymes relevant for hyperglycemia (α-amylase and α-glucosidase) and hypertension (angiotensin I-converting enzyme, ACE-I) management. Leaves and flowers had higher TPC and AC than fruits and hydroxycinnamic acid derivatives were found in all structures by HPLC. Chlorogenic acid and quercetin derivatives were detected only in leaves and flowers, which also inhibited the α-amylase and α-glucosidase enzymes, but flowers showed the highest anti-hyperglycemia activity. No inhibition of ACE-I and hyperglycemia-relevant enzymes were found in loquat fruits; additionally, TPC and AC were high at the green stage. Loquat leaves and flowers are sources of phenolic bioactives with potential for diet-based hyperglycemia management. No triterpenic acids were found in any of the loquat parts.info:eu-repo/semantics/openAccessPontificia Universidad Católica de Chile. Facultad de Agronomía e Ingeniería ForestalCiencia e investigación agraria v.44 n.3 20172017-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-16202017000300272en10.7764/rcia.v44i3.1816
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Eriobotrya japonica phenolic compounds antioxidants anti-hyperglycemia loquat
spellingShingle	Eriobotrya japonica phenolic compounds antioxidants anti-hyperglycemia loquat Ahumada,Jaime Fuentealba,Claudia Olaeta,José A. Undurraga,Pedro Pedreschi,Romina Shetty,Kalidas Chirinos,Rosana Campos,David Ranilla,Lena Gálvez Bioactive compounds of loquat (Eriobotrya japonica Lindl.) cv. Golden Nugget and analysis of in vitro functionality for hyperglycemia management
description	Abstract The loquat cultivar Golden Nugget (leaves, flowers and fruits), which has potential commercial importance in Chile, was analyzed for targeted bioactive composition (total phenolic contents: TPC, phenolic profiles and triterpenic acids) and in vitro bioactivity such as antioxidant capacity (AC) and inhibitory activity against enzymes relevant for hyperglycemia (α-amylase and α-glucosidase) and hypertension (angiotensin I-converting enzyme, ACE-I) management. Leaves and flowers had higher TPC and AC than fruits and hydroxycinnamic acid derivatives were found in all structures by HPLC. Chlorogenic acid and quercetin derivatives were detected only in leaves and flowers, which also inhibited the α-amylase and α-glucosidase enzymes, but flowers showed the highest anti-hyperglycemia activity. No inhibition of ACE-I and hyperglycemia-relevant enzymes were found in loquat fruits; additionally, TPC and AC were high at the green stage. Loquat leaves and flowers are sources of phenolic bioactives with potential for diet-based hyperglycemia management. No triterpenic acids were found in any of the loquat parts.
author	Ahumada,Jaime Fuentealba,Claudia Olaeta,José A. Undurraga,Pedro Pedreschi,Romina Shetty,Kalidas Chirinos,Rosana Campos,David Ranilla,Lena Gálvez
author_facet	Ahumada,Jaime Fuentealba,Claudia Olaeta,José A. Undurraga,Pedro Pedreschi,Romina Shetty,Kalidas Chirinos,Rosana Campos,David Ranilla,Lena Gálvez
author_sort	Ahumada,Jaime
title	Bioactive compounds of loquat (Eriobotrya japonica Lindl.) cv. Golden Nugget and analysis of in vitro functionality for hyperglycemia management
title_short	Bioactive compounds of loquat (Eriobotrya japonica Lindl.) cv. Golden Nugget and analysis of in vitro functionality for hyperglycemia management
title_full	Bioactive compounds of loquat (Eriobotrya japonica Lindl.) cv. Golden Nugget and analysis of in vitro functionality for hyperglycemia management
title_fullStr	Bioactive compounds of loquat (Eriobotrya japonica Lindl.) cv. Golden Nugget and analysis of in vitro functionality for hyperglycemia management
title_full_unstemmed	Bioactive compounds of loquat (Eriobotrya japonica Lindl.) cv. Golden Nugget and analysis of in vitro functionality for hyperglycemia management
title_sort	bioactive compounds of loquat (eriobotrya japonica lindl.) cv. golden nugget and analysis of in vitro functionality for hyperglycemia management
publisher	Pontificia Universidad Católica de Chile. Facultad de Agronomía e Ingeniería Forestal
publishDate	2017
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-16202017000300272
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Bioactive compounds of loquat (Eriobotrya japonica Lindl.) cv. Golden Nugget and analysis of in vitro functionality for hyperglycemia management

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