Antimicrobial Susceptibility to ß-lactams and Metronidazole of Microorganisms Isolated from Chronic and Aggressive Periodontitis

The objective of this study was to evaluate the microbial susceptibility to ß-lactams and metronidazole, and evaluate the production of ß-lactamases by microorganisms isolated from patients with chronic or aggressive periodontitis. The samples were obtained from 50 patients with periodontitis and mi...

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Autores principales:	Gaetti-Jardim Júnior,Elerson, Schweitzer,Christiane Marie
Lenguaje:	English
Publicado:	Universidad de La Frontera. Facultad de Medicina 2013
Materias:	periodontitis antimicrobials ß-lactams bacteria metronidazole
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-381X2013000200005
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spelling	oai:scielo:S0718-381X20130002000052013-11-04Antimicrobial Susceptibility to ß-lactams and Metronidazole of Microorganisms Isolated from Chronic and Aggressive PeriodontitisGaetti-Jardim Júnior,ElersonSchweitzer,Christiane Marie periodontitis antimicrobials ß-lactams bacteria metronidazole The objective of this study was to evaluate the microbial susceptibility to ß-lactams and metronidazole, and evaluate the production of ß-lactamases by microorganisms isolated from patients with chronic or aggressive periodontitis. The samples were obtained from 50 patients with periodontitis and microorganisms were isolated onto selective and nonselective culture media, identified by biochemical methods and tested for susceptibility to antimicrobial agents (amoxicillin, amoxicillin/clavulanate, cefoxitin, imipenem, metronidazole, penicillin G). The isolates were resistant to at least 1 mg/ml of any drug tested were evaluated to verify the production of ß-lactamases by the method of double layer (or biological) and chromogenic cephalosporin using nitrocefin. The results evidenced resistance to amoxicillin and penicillin G, while the susceptibility to association amoxicillin/clavulanate, imipenem and cefoxitin was widely disseminated among the organisms. Resistance to these drugs showed a clear correlation with the production of ß-lactamase in the majority of microbial groups.info:eu-repo/semantics/openAccessUniversidad de La Frontera. Facultad de MedicinaInternational journal of odontostomatology v.7 n.2 20132013-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-381X2013000200005en10.4067/S0718-381X2013000200005
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	periodontitis antimicrobials ß-lactams bacteria metronidazole
spellingShingle	periodontitis antimicrobials ß-lactams bacteria metronidazole Gaetti-Jardim Júnior,Elerson Schweitzer,Christiane Marie Antimicrobial Susceptibility to ß-lactams and Metronidazole of Microorganisms Isolated from Chronic and Aggressive Periodontitis
description	The objective of this study was to evaluate the microbial susceptibility to ß-lactams and metronidazole, and evaluate the production of ß-lactamases by microorganisms isolated from patients with chronic or aggressive periodontitis. The samples were obtained from 50 patients with periodontitis and microorganisms were isolated onto selective and nonselective culture media, identified by biochemical methods and tested for susceptibility to antimicrobial agents (amoxicillin, amoxicillin/clavulanate, cefoxitin, imipenem, metronidazole, penicillin G). The isolates were resistant to at least 1 mg/ml of any drug tested were evaluated to verify the production of ß-lactamases by the method of double layer (or biological) and chromogenic cephalosporin using nitrocefin. The results evidenced resistance to amoxicillin and penicillin G, while the susceptibility to association amoxicillin/clavulanate, imipenem and cefoxitin was widely disseminated among the organisms. Resistance to these drugs showed a clear correlation with the production of ß-lactamase in the majority of microbial groups.
author	Gaetti-Jardim Júnior,Elerson Schweitzer,Christiane Marie
author_facet	Gaetti-Jardim Júnior,Elerson Schweitzer,Christiane Marie
author_sort	Gaetti-Jardim Júnior,Elerson
title	Antimicrobial Susceptibility to ß-lactams and Metronidazole of Microorganisms Isolated from Chronic and Aggressive Periodontitis
title_short	Antimicrobial Susceptibility to ß-lactams and Metronidazole of Microorganisms Isolated from Chronic and Aggressive Periodontitis
title_full	Antimicrobial Susceptibility to ß-lactams and Metronidazole of Microorganisms Isolated from Chronic and Aggressive Periodontitis
title_fullStr	Antimicrobial Susceptibility to ß-lactams and Metronidazole of Microorganisms Isolated from Chronic and Aggressive Periodontitis
title_full_unstemmed	Antimicrobial Susceptibility to ß-lactams and Metronidazole of Microorganisms Isolated from Chronic and Aggressive Periodontitis
title_sort	antimicrobial susceptibility to ß-lactams and metronidazole of microorganisms isolated from chronic and aggressive periodontitis
publisher	Universidad de La Frontera. Facultad de Medicina
publishDate	2013
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-381X2013000200005
work_keys_str_mv	AT gaettijardimjuniorelerson antimicrobialsusceptibilitytoßlactamsandmetronidazoleofmicroorganismsisolatedfromchronicandaggressiveperiodontitis AT schweitzerchristianemarie antimicrobialsusceptibilitytoßlactamsandmetronidazoleofmicroorganismsisolatedfromchronicandaggressiveperiodontitis
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Antimicrobial Susceptibility to ß-lactams and Metronidazole of Microorganisms Isolated from Chronic and Aggressive Periodontitis

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