Primary Adenocarcinoma of the Colon with Metastases to the Mandible and Liver: A Case Report

Metastatic lesions to the mandible may be originated from primary tumors elsewhere in the body. However, metastatic colonic carcinomas to this bone have been described infrequently. We report the case of a 71-year-old man with an adenocarcinoma in the sigmoid colon with liver metastasis. The patient...

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Autores principales:	Andrade,Ana Luiza Dias Leite de, Gordón-Núñez,Manuel Antonio, Galvão,Rodrigo Cavalcanti Duarte, Fernades,Gustavo Alberto Freire, Santos,Edilmar de Moura, Galvão,Hébel Cavalcanti
Lenguaje:	English
Publicado:	Universidad de La Frontera. Facultad de Medicina 2015
Materias:	adenocarcinoma colonic neoplasms mandible neoplasm metastasis neoplasias del colon mandíbula metástasis neoplásica
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-381X2015000200019
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spelling	oai:scielo:S0718-381X20150002000192016-03-22Primary Adenocarcinoma of the Colon with Metastases to the Mandible and Liver: A Case ReportAndrade,Ana Luiza Dias Leite deGordón-Núñez,Manuel AntonioGalvão,Rodrigo Cavalcanti DuarteFernades,Gustavo Alberto FreireSantos,Edilmar de MouraGalvão,Hébel Cavalcanti adenocarcinoma colonic neoplasms mandible neoplasm metastasis adenocarcinoma neoplasias del colon mandíbula metástasis neoplásica Metastatic lesions to the mandible may be originated from primary tumors elsewhere in the body. However, metastatic colonic carcinomas to this bone have been described infrequently. We report the case of a 71-year-old man with an adenocarcinoma in the sigmoid colon with liver metastasis. The patient underwent chemotherapy with indication of sigmoidectomy and retroperitoneal lymphadenectomy. One year and four months after the first metastatic diagnosis, the patient presented a tumor mass in the body and branch of the right mandible. Histopathological and immunohistochemical analysis with monoclonal antibodies specific for CEA, CK20, CDX-2, and vilin were compatible with the diagnosis of moderately differentiated metastatic adenocarcinoma with colonic origin. However, due to the wide spread of the disease, the patient died four months later. Tumor markers have been applied in clinical practice to assist in the diagnosis and to help guide prognosis, staging and treatment of cancer. The management of metastatic lesions remains a controversial issue and the development of new and more specific markers of gastrointestinal differentiation that may promote early diagnosis, are of continuous interest.info:eu-repo/semantics/openAccessUniversidad de La Frontera. Facultad de MedicinaInternational journal of odontostomatology v.9 n.2 20152015-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-381X2015000200019en10.4067/S0718-381X2015000200019
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	adenocarcinoma colonic neoplasms mandible neoplasm metastasis adenocarcinoma neoplasias del colon mandíbula metástasis neoplásica
spellingShingle	adenocarcinoma colonic neoplasms mandible neoplasm metastasis adenocarcinoma neoplasias del colon mandíbula metástasis neoplásica Andrade,Ana Luiza Dias Leite de Gordón-Núñez,Manuel Antonio Galvão,Rodrigo Cavalcanti Duarte Fernades,Gustavo Alberto Freire Santos,Edilmar de Moura Galvão,Hébel Cavalcanti Primary Adenocarcinoma of the Colon with Metastases to the Mandible and Liver: A Case Report
description	Metastatic lesions to the mandible may be originated from primary tumors elsewhere in the body. However, metastatic colonic carcinomas to this bone have been described infrequently. We report the case of a 71-year-old man with an adenocarcinoma in the sigmoid colon with liver metastasis. The patient underwent chemotherapy with indication of sigmoidectomy and retroperitoneal lymphadenectomy. One year and four months after the first metastatic diagnosis, the patient presented a tumor mass in the body and branch of the right mandible. Histopathological and immunohistochemical analysis with monoclonal antibodies specific for CEA, CK20, CDX-2, and vilin were compatible with the diagnosis of moderately differentiated metastatic adenocarcinoma with colonic origin. However, due to the wide spread of the disease, the patient died four months later. Tumor markers have been applied in clinical practice to assist in the diagnosis and to help guide prognosis, staging and treatment of cancer. The management of metastatic lesions remains a controversial issue and the development of new and more specific markers of gastrointestinal differentiation that may promote early diagnosis, are of continuous interest.
author	Andrade,Ana Luiza Dias Leite de Gordón-Núñez,Manuel Antonio Galvão,Rodrigo Cavalcanti Duarte Fernades,Gustavo Alberto Freire Santos,Edilmar de Moura Galvão,Hébel Cavalcanti
author_facet	Andrade,Ana Luiza Dias Leite de Gordón-Núñez,Manuel Antonio Galvão,Rodrigo Cavalcanti Duarte Fernades,Gustavo Alberto Freire Santos,Edilmar de Moura Galvão,Hébel Cavalcanti
author_sort	Andrade,Ana Luiza Dias Leite de
title	Primary Adenocarcinoma of the Colon with Metastases to the Mandible and Liver: A Case Report
title_short	Primary Adenocarcinoma of the Colon with Metastases to the Mandible and Liver: A Case Report
title_full	Primary Adenocarcinoma of the Colon with Metastases to the Mandible and Liver: A Case Report
title_fullStr	Primary Adenocarcinoma of the Colon with Metastases to the Mandible and Liver: A Case Report
title_full_unstemmed	Primary Adenocarcinoma of the Colon with Metastases to the Mandible and Liver: A Case Report
title_sort	primary adenocarcinoma of the colon with metastases to the mandible and liver: a case report
publisher	Universidad de La Frontera. Facultad de Medicina
publishDate	2015
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-381X2015000200019
work_keys_str_mv	AT andradeanaluizadiasleitede primaryadenocarcinomaofthecolonwithmetastasestothemandibleandliveracasereport AT gordonnunezmanuelantonio primaryadenocarcinomaofthecolonwithmetastasestothemandibleandliveracasereport AT galvaorodrigocavalcantiduarte primaryadenocarcinomaofthecolonwithmetastasestothemandibleandliveracasereport AT fernadesgustavoalbertofreire primaryadenocarcinomaofthecolonwithmetastasestothemandibleandliveracasereport AT santosedilmardemoura primaryadenocarcinomaofthecolonwithmetastasestothemandibleandliveracasereport AT galvaohebelcavalcanti primaryadenocarcinomaofthecolonwithmetastasestothemandibleandliveracasereport
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Primary Adenocarcinoma of the Colon with Metastases to the Mandible and Liver: A Case Report

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