Copper Nanoparticles as Potential Antimicrobial Agent in Disinfecting Root Canals: A Systematic Review

Copper was registered as the first solid antimicrobial material. Its availability makes it an important option as an antibacterial agent. At nanoparticle size it does not exceed 100 nm, allowing close interaction with microbial membranes, enhancing its effect even more. Copper generates toxic hydrox...

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Autores principales:	Sánchez-Sanhueza,Gabriela, Fuentes-Rodríguez,Daniela, Bello-Toledo,Helia
Lenguaje:	English
Publicado:	Universidad de La Frontera. Facultad de Medicina 2016
Materias:	copper nanoparticles antibacterial endodontics
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-381X2016000300024
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spelling	oai:scielo:S0718-381X20160003000242017-02-15Copper Nanoparticles as Potential Antimicrobial Agent in Disinfecting Root Canals: A Systematic ReviewSánchez-Sanhueza,GabrielaFuentes-Rodríguez,DanielaBello-Toledo,Helia copper nanoparticles antibacterial endodontics Copper was registered as the first solid antimicrobial material. Its availability makes it an important option as an antibacterial agent. At nanoparticle size it does not exceed 100 nm, allowing close interaction with microbial membranes, enhancing its effect even more. Copper generates toxic hydroxyl radicals that damage cell membranes of Gram-negative and Gram-positive bacteria, among the latter, Enterococcus faecalis, which are present in infected radicular canals. Synthesis of metal nanoparticles with antimicrobial properties has become a viable alternative and has promising applications in the fight against pathogenic microorganisms. Furthermore, the use of some polymers to stabilize nanoparticles increases their release time and may as well decrease the risk of bacterial recolonization and biofilm formation within the ducts, enhancing the antimicrobial properties of these compounds.The aim of this article is to conduct a systematic review of the literature on antimicrobial copper nanoparticles, their current applications and their potential use in the area of oral health, specifically in the field of endodontics.info:eu-repo/semantics/openAccessUniversidad de La Frontera. Facultad de MedicinaInternational journal of odontostomatology v.10 n.3 20162016-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-381X2016000300024en10.4067/S0718-381X2016000300024
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	copper nanoparticles antibacterial endodontics
spellingShingle	copper nanoparticles antibacterial endodontics Sánchez-Sanhueza,Gabriela Fuentes-Rodríguez,Daniela Bello-Toledo,Helia Copper Nanoparticles as Potential Antimicrobial Agent in Disinfecting Root Canals: A Systematic Review
description	Copper was registered as the first solid antimicrobial material. Its availability makes it an important option as an antibacterial agent. At nanoparticle size it does not exceed 100 nm, allowing close interaction with microbial membranes, enhancing its effect even more. Copper generates toxic hydroxyl radicals that damage cell membranes of Gram-negative and Gram-positive bacteria, among the latter, Enterococcus faecalis, which are present in infected radicular canals. Synthesis of metal nanoparticles with antimicrobial properties has become a viable alternative and has promising applications in the fight against pathogenic microorganisms. Furthermore, the use of some polymers to stabilize nanoparticles increases their release time and may as well decrease the risk of bacterial recolonization and biofilm formation within the ducts, enhancing the antimicrobial properties of these compounds.The aim of this article is to conduct a systematic review of the literature on antimicrobial copper nanoparticles, their current applications and their potential use in the area of oral health, specifically in the field of endodontics.
author	Sánchez-Sanhueza,Gabriela Fuentes-Rodríguez,Daniela Bello-Toledo,Helia
author_facet	Sánchez-Sanhueza,Gabriela Fuentes-Rodríguez,Daniela Bello-Toledo,Helia
author_sort	Sánchez-Sanhueza,Gabriela
title	Copper Nanoparticles as Potential Antimicrobial Agent in Disinfecting Root Canals: A Systematic Review
title_short	Copper Nanoparticles as Potential Antimicrobial Agent in Disinfecting Root Canals: A Systematic Review
title_full	Copper Nanoparticles as Potential Antimicrobial Agent in Disinfecting Root Canals: A Systematic Review
title_fullStr	Copper Nanoparticles as Potential Antimicrobial Agent in Disinfecting Root Canals: A Systematic Review
title_full_unstemmed	Copper Nanoparticles as Potential Antimicrobial Agent in Disinfecting Root Canals: A Systematic Review
title_sort	copper nanoparticles as potential antimicrobial agent in disinfecting root canals: a systematic review
publisher	Universidad de La Frontera. Facultad de Medicina
publishDate	2016
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-381X2016000300024
work_keys_str_mv	AT sanchezsanhuezagabriela coppernanoparticlesaspotentialantimicrobialagentindisinfectingrootcanalsasystematicreview AT fuentesrodriguezdaniela coppernanoparticlesaspotentialantimicrobialagentindisinfectingrootcanalsasystematicreview AT bellotoledohelia coppernanoparticlesaspotentialantimicrobialagentindisinfectingrootcanalsasystematicreview
_version_	1714203987317620736

Copper Nanoparticles as Potential Antimicrobial Agent in Disinfecting Root Canals: A Systematic Review

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