COX-2 Inhibitors in Dental Pain Management

ABSTRACT: Pain is a major symptom in many dental procedures. Studies show consistently that pain, including dental pain, is not effectively treated; management of pain is a critical and challenging component in dentistry. Improvement and efficacy on the treatment depends on knowing which treatments...

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Autores principales:	Del-Muro-Casas,Fatima Erendida, Gómez-Coronado,Karina, Rodríguez-Guajardo,Nelly Alejandra, Varela-Parga,Manuel, Luengo-Ferreira,Jesús Alberto, Medrano-Rodríguez,Juan Carlos
Lenguaje:	English
Publicado:	Universidad de La Frontera. Facultad de Medicina 2018
Materias:	Pharmacology cox-2 inhibitors dental pain
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-381X2018000300225
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id	oai:scielo:S0718-381X2018000300225
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spelling	oai:scielo:S0718-381X20180003002252018-10-26COX-2 Inhibitors in Dental Pain ManagementDel-Muro-Casas,Fatima ErendidaGómez-Coronado,KarinaRodríguez-Guajardo,Nelly AlejandraVarela-Parga,ManuelLuengo-Ferreira,Jesús AlbertoMedrano-Rodríguez,Juan Carlos Pharmacology cox-2 inhibitors dental pain ABSTRACT: Pain is a major symptom in many dental procedures. Studies show consistently that pain, including dental pain, is not effectively treated; management of pain is a critical and challenging component in dentistry. Improvement and efficacy on the treatment depends on knowing which treatments are the most effective. Knowing how well an analgesic works and its associated adverse effects is fundamental to clinical decision. The aim of this review is to provide information to the dentistry field on the treatment of dental pain specifically with COX-2 inhibitors providing a useful guide to dentist on controlling pain. Therefore, nonsteroidal anti-inflammatory drugs (NSAIDs) are the most commonly prescribed analgesic agents in surgical outpatients. Major limitations of NSAIDs are their gastrointestinal (GI) adverse events (perforation, ulceration, and bleeding), impairment of hemostatic function, and renal failure (with long-term therapy). A new class of NSAIDs, COX2 selective inhibitors (Coxibs), have been developed with the aim of reducing the GI adverse events of traditional NSAIDs while maintaining their effective anti-inflammatory and analgesic properties.info:eu-repo/semantics/openAccessUniversidad de La Frontera. Facultad de MedicinaInternational journal of odontostomatology v.12 n.3 20182018-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-381X2018000300225en10.4067/S0718-381X2018000300225
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Pharmacology cox-2 inhibitors dental pain
spellingShingle	Pharmacology cox-2 inhibitors dental pain Del-Muro-Casas,Fatima Erendida Gómez-Coronado,Karina Rodríguez-Guajardo,Nelly Alejandra Varela-Parga,Manuel Luengo-Ferreira,Jesús Alberto Medrano-Rodríguez,Juan Carlos COX-2 Inhibitors in Dental Pain Management
description	ABSTRACT: Pain is a major symptom in many dental procedures. Studies show consistently that pain, including dental pain, is not effectively treated; management of pain is a critical and challenging component in dentistry. Improvement and efficacy on the treatment depends on knowing which treatments are the most effective. Knowing how well an analgesic works and its associated adverse effects is fundamental to clinical decision. The aim of this review is to provide information to the dentistry field on the treatment of dental pain specifically with COX-2 inhibitors providing a useful guide to dentist on controlling pain. Therefore, nonsteroidal anti-inflammatory drugs (NSAIDs) are the most commonly prescribed analgesic agents in surgical outpatients. Major limitations of NSAIDs are their gastrointestinal (GI) adverse events (perforation, ulceration, and bleeding), impairment of hemostatic function, and renal failure (with long-term therapy). A new class of NSAIDs, COX2 selective inhibitors (Coxibs), have been developed with the aim of reducing the GI adverse events of traditional NSAIDs while maintaining their effective anti-inflammatory and analgesic properties.
author	Del-Muro-Casas,Fatima Erendida Gómez-Coronado,Karina Rodríguez-Guajardo,Nelly Alejandra Varela-Parga,Manuel Luengo-Ferreira,Jesús Alberto Medrano-Rodríguez,Juan Carlos
author_facet	Del-Muro-Casas,Fatima Erendida Gómez-Coronado,Karina Rodríguez-Guajardo,Nelly Alejandra Varela-Parga,Manuel Luengo-Ferreira,Jesús Alberto Medrano-Rodríguez,Juan Carlos
author_sort	Del-Muro-Casas,Fatima Erendida
title	COX-2 Inhibitors in Dental Pain Management
title_short	COX-2 Inhibitors in Dental Pain Management
title_full	COX-2 Inhibitors in Dental Pain Management
title_fullStr	COX-2 Inhibitors in Dental Pain Management
title_full_unstemmed	COX-2 Inhibitors in Dental Pain Management
title_sort	cox-2 inhibitors in dental pain management
publisher	Universidad de La Frontera. Facultad de Medicina
publishDate	2018
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-381X2018000300225
work_keys_str_mv	AT delmurocasasfatimaerendida cox2inhibitorsindentalpainmanagement AT gomezcoronadokarina cox2inhibitorsindentalpainmanagement AT rodriguezguajardonellyalejandra cox2inhibitorsindentalpainmanagement AT varelapargamanuel cox2inhibitorsindentalpainmanagement AT luengoferreirajesusalberto cox2inhibitorsindentalpainmanagement AT medranorodriguezjuancarlos cox2inhibitorsindentalpainmanagement
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COX-2 Inhibitors in Dental Pain Management

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