PLA/PGA and its co-Polymers in Alveolar Bone Regeneration. A Systematic Review

ABSTRACT: The aim of this research was to perform a systematic review to identify the most frequent uses of PLA/ PGA in alveolar bone regeneration and their results. A study was designed to answer the question: What are the most frequent uses of PLA/PLGA and their copolymers in alveolar bone regener...

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Autores principales:	Parra,Marcelo, Moya,María Paz, Rebolledo,Carolina, Haidar,Ziyad S, Alister,Juan Pablo, Olate,Sergio
Lenguaje:	English
Publicado:	Universidad de La Frontera. Facultad de Medicina 2019
Materias:	poly lactic acid poly ethylene glycol bone substitute bone grafting
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-381X2019000300258
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spelling	oai:scielo:S0718-381X20190003002582019-08-09PLA/PGA and its co-Polymers in Alveolar Bone Regeneration. A Systematic ReviewParra,MarceloMoya,María PazRebolledo,CarolinaHaidar,Ziyad SAlister,Juan PabloOlate,Sergio poly lactic acid poly ethylene glycol bone substitute bone grafting ABSTRACT: The aim of this research was to perform a systematic review to identify the most frequent uses of PLA/ PGA in alveolar bone regeneration and their results. A study was designed to answer the question: What are the most frequent uses of PLA/PLGA and their copolymers in alveolar bone regeneration?. A systematic search was done on MEDLINE, EMBASE and LILACS from April 1993 to December 2017. The search string used on MEDLINE was: (((polylactic acid) OR PLA) OR PLA-based copolymers) OR PLA blends) OR PLA scaffolds)) AND ((("Bone Regeneration"[Mesh]) OR bone regeneration) OR guided bone regeneration). The search was complemented by a manual review of the references from the articles included. Most of the studies selected were weak and, regarding the most frequent uses of PLA/PGA, 13 studies used it as a resorbable membrane, two as an absorbable mesh, one as an absorbable screw and three as filling material. Based on our results, the authors consider that PLA/PGA requires a delicate relation between the mechanical resistance and the degradation process. PLA/PGA does not interrupt bone regeneration; however, the influence in cellular events related to bone regeneration and later osseointegration have not been identified.info:eu-repo/semantics/openAccessUniversidad de La Frontera. Facultad de MedicinaInternational journal of odontostomatology v.13 n.3 20192019-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-381X2019000300258en10.4067/S0718-381X2019000300258
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	poly lactic acid poly ethylene glycol bone substitute bone grafting
spellingShingle	poly lactic acid poly ethylene glycol bone substitute bone grafting Parra,Marcelo Moya,María Paz Rebolledo,Carolina Haidar,Ziyad S Alister,Juan Pablo Olate,Sergio PLA/PGA and its co-Polymers in Alveolar Bone Regeneration. A Systematic Review
description	ABSTRACT: The aim of this research was to perform a systematic review to identify the most frequent uses of PLA/ PGA in alveolar bone regeneration and their results. A study was designed to answer the question: What are the most frequent uses of PLA/PLGA and their copolymers in alveolar bone regeneration?. A systematic search was done on MEDLINE, EMBASE and LILACS from April 1993 to December 2017. The search string used on MEDLINE was: (((polylactic acid) OR PLA) OR PLA-based copolymers) OR PLA blends) OR PLA scaffolds)) AND ((("Bone Regeneration"[Mesh]) OR bone regeneration) OR guided bone regeneration). The search was complemented by a manual review of the references from the articles included. Most of the studies selected were weak and, regarding the most frequent uses of PLA/PGA, 13 studies used it as a resorbable membrane, two as an absorbable mesh, one as an absorbable screw and three as filling material. Based on our results, the authors consider that PLA/PGA requires a delicate relation between the mechanical resistance and the degradation process. PLA/PGA does not interrupt bone regeneration; however, the influence in cellular events related to bone regeneration and later osseointegration have not been identified.
author	Parra,Marcelo Moya,María Paz Rebolledo,Carolina Haidar,Ziyad S Alister,Juan Pablo Olate,Sergio
author_facet	Parra,Marcelo Moya,María Paz Rebolledo,Carolina Haidar,Ziyad S Alister,Juan Pablo Olate,Sergio
author_sort	Parra,Marcelo
title	PLA/PGA and its co-Polymers in Alveolar Bone Regeneration. A Systematic Review
title_short	PLA/PGA and its co-Polymers in Alveolar Bone Regeneration. A Systematic Review
title_full	PLA/PGA and its co-Polymers in Alveolar Bone Regeneration. A Systematic Review
title_fullStr	PLA/PGA and its co-Polymers in Alveolar Bone Regeneration. A Systematic Review
title_full_unstemmed	PLA/PGA and its co-Polymers in Alveolar Bone Regeneration. A Systematic Review
title_sort	pla/pga and its co-polymers in alveolar bone regeneration. a systematic review
publisher	Universidad de La Frontera. Facultad de Medicina
publishDate	2019
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-381X2019000300258
work_keys_str_mv	AT parramarcelo plapgaanditscopolymersinalveolarboneregenerationasystematicreview AT moyamariapaz plapgaanditscopolymersinalveolarboneregenerationasystematicreview AT rebolledocarolina plapgaanditscopolymersinalveolarboneregenerationasystematicreview AT haidarziyads plapgaanditscopolymersinalveolarboneregenerationasystematicreview AT alisterjuanpablo plapgaanditscopolymersinalveolarboneregenerationasystematicreview AT olatesergio plapgaanditscopolymersinalveolarboneregenerationasystematicreview
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PLA/PGA and its co-Polymers in Alveolar Bone Regeneration. A Systematic Review

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