Osteoradionecrosis in a Patient Submitted to Head and Neck Radiotherapy: A Case Report

ABSTRACT: Radiotherapy applies ionizing radiation at predetermined doses for a limited period of time in order to destroy tumors. The oral cavity, which has a high rate of cell renewal, is affected by the side effects of radiotherapy including osteoradionecrosis (ORN). This condition occurs due to i...

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Autores principales: Ferreira,Karla Daniella Malta, Corrêa,Patrícia Dias, Balenzio,Giovanna Rodrigues, Pigatti,Fernanda Mombrini, Ferreira,Dennis de Carvalho, Tannure,Patricia Nivoloni
Lenguaje:English
Publicado: Universidad de La Frontera. Facultad de Medicina 2019
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-381X2019000400428
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spelling oai:scielo:S0718-381X20190004004282019-10-07Osteoradionecrosis in a Patient Submitted to Head and Neck Radiotherapy: A Case ReportFerreira,Karla Daniella MaltaCorrêa,Patrícia DiasBalenzio,Giovanna RodriguesPigatti,Fernanda MombriniFerreira,Dennis de CarvalhoTannure,Patricia Nivoloni osteoradionecrosis radiotherapy head and neck neoplasms mandibular osteotomy ABSTRACT: Radiotherapy applies ionizing radiation at predetermined doses for a limited period of time in order to destroy tumors. The oral cavity, which has a high rate of cell renewal, is affected by the side effects of radiotherapy including osteoradionecrosis (ORN). This condition occurs due to irradiated bone tissue that becomes devitalized and exposed in the oral cavity. Conservative therapies are recommended for ORN lesions that are not extensive or in an early stage. Surgical intervention is necessary for extensive areas affected by necrosis. This study reports a case of ORN in the left mandibular body which resulted in a pathological fracture. The treatment consisted of segmental mandibulectomy and the use of a reconstruction plate. Also, low-level laser therapy around bone exposure was performed. After surgery, the patient underwent 6 months of follow-up and was satisfied with the outcome. However, the patient died before control of ORN was achieved due to a heart attack.info:eu-repo/semantics/openAccessUniversidad de La Frontera. Facultad de MedicinaInternational journal of odontostomatology v.13 n.4 20192019-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-381X2019000400428en10.4067/S0718-381X2019000400428
institution Scielo Chile
collection Scielo Chile
language English
topic osteoradionecrosis
radiotherapy
head and neck neoplasms
mandibular osteotomy
spellingShingle osteoradionecrosis
radiotherapy
head and neck neoplasms
mandibular osteotomy
Ferreira,Karla Daniella Malta
Corrêa,Patrícia Dias
Balenzio,Giovanna Rodrigues
Pigatti,Fernanda Mombrini
Ferreira,Dennis de Carvalho
Tannure,Patricia Nivoloni
Osteoradionecrosis in a Patient Submitted to Head and Neck Radiotherapy: A Case Report
description ABSTRACT: Radiotherapy applies ionizing radiation at predetermined doses for a limited period of time in order to destroy tumors. The oral cavity, which has a high rate of cell renewal, is affected by the side effects of radiotherapy including osteoradionecrosis (ORN). This condition occurs due to irradiated bone tissue that becomes devitalized and exposed in the oral cavity. Conservative therapies are recommended for ORN lesions that are not extensive or in an early stage. Surgical intervention is necessary for extensive areas affected by necrosis. This study reports a case of ORN in the left mandibular body which resulted in a pathological fracture. The treatment consisted of segmental mandibulectomy and the use of a reconstruction plate. Also, low-level laser therapy around bone exposure was performed. After surgery, the patient underwent 6 months of follow-up and was satisfied with the outcome. However, the patient died before control of ORN was achieved due to a heart attack.
author Ferreira,Karla Daniella Malta
Corrêa,Patrícia Dias
Balenzio,Giovanna Rodrigues
Pigatti,Fernanda Mombrini
Ferreira,Dennis de Carvalho
Tannure,Patricia Nivoloni
author_facet Ferreira,Karla Daniella Malta
Corrêa,Patrícia Dias
Balenzio,Giovanna Rodrigues
Pigatti,Fernanda Mombrini
Ferreira,Dennis de Carvalho
Tannure,Patricia Nivoloni
author_sort Ferreira,Karla Daniella Malta
title Osteoradionecrosis in a Patient Submitted to Head and Neck Radiotherapy: A Case Report
title_short Osteoradionecrosis in a Patient Submitted to Head and Neck Radiotherapy: A Case Report
title_full Osteoradionecrosis in a Patient Submitted to Head and Neck Radiotherapy: A Case Report
title_fullStr Osteoradionecrosis in a Patient Submitted to Head and Neck Radiotherapy: A Case Report
title_full_unstemmed Osteoradionecrosis in a Patient Submitted to Head and Neck Radiotherapy: A Case Report
title_sort osteoradionecrosis in a patient submitted to head and neck radiotherapy: a case report
publisher Universidad de La Frontera. Facultad de Medicina
publishDate 2019
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-381X2019000400428
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