Evaluation of a Protocol For Topical Application of Capsaicine Gel 0.025 % in the Management of Burning Mouth Syndrome Correlating its Impact on Quality of Life

ABSTRACT: The aim of this study is to report the results obtained with a protocol of topical application of capsaicin gel 0.025 % in the management of burning mouth syndrome (BMS) to evaluate the influence of the disease and treatment on their quality of life (QOL) using the OHIP-14 questionnaire (O...

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Auteurs principaux: Ricken,Carla Militão, Péder,Silvia Natalia Souza de, Kamikawa,Daniela Suemi, Pieralisi,Neli, Chicarelli,Mariliani, Tolentino,Elen de Souza
Langue:English
Publié: Universidad de La Frontera. Facultad de Medicina 2021
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spelling oai:scielo:S0718-381X20210002004432021-06-08Evaluation of a Protocol For Topical Application of Capsaicine Gel 0.025 % in the Management of Burning Mouth Syndrome Correlating its Impact on Quality of LifeRicken,Carla MilitãoPéder,Silvia Natalia Souza deKamikawa,Daniela SuemiPieralisi,NeliChicarelli,MarilianiTolentino,Elen de Souza Burning mouth syndrome capsaicin quality of life ABSTRACT: The aim of this study is to report the results obtained with a protocol of topical application of capsaicin gel 0.025 % in the management of burning mouth syndrome (BMS) to evaluate the influence of the disease and treatment on their quality of life (QOL) using the OHIP-14 questionnaire (Oral Health Impact Profile). After clinical examination and diagnosis of BMS, 10 patients reported the intensity of the burning by means of a subjective score ranging from 0 to 10 and also answered the OHIP-14. Then, a topical application protocol of capsaicin gel 0.025 % was initiated, with weaning from medication and complete withdrawal within 180 days. At each reassessment consultation (30, 60, 90 and 180 days), the patients answered the OHIP-14 and subjective burning scores were collected again. Overall, the capsaicin gel showed gradual reduction or elimination of symptoms of BMS, as well as an improvement in the QOL of patients throughout treatment. At 180 days, after medication withdrawal, 6 patients (60 %) reported total absence of burning and in four patients (40 %) the score remained or decreased. In one patient (10 %) the score increased, although it remained below the initial score. The results showed an improvement in the QOL of all patients who completed the protocol and the impact of BMS on the QOL decreased in relation to the initial score in all patients. The topical use of 0.025 % capsaicin gel was effective in reducing or remitting symptoms of BMS. The OHIP-14 questionnaire showed the negative impact of BMS on patients' QOL and the role of treatment in its improvement.info:eu-repo/semantics/openAccessUniversidad de La Frontera. Facultad de MedicinaInternational journal of odontostomatology v.15 n.2 20212021-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-381X2021000200443en10.4067/S0718-381X2021000200443
institution Scielo Chile
collection Scielo Chile
language English
topic Burning mouth syndrome
capsaicin
quality of life
spellingShingle Burning mouth syndrome
capsaicin
quality of life
Ricken,Carla Militão
Péder,Silvia Natalia Souza de
Kamikawa,Daniela Suemi
Pieralisi,Neli
Chicarelli,Mariliani
Tolentino,Elen de Souza
Evaluation of a Protocol For Topical Application of Capsaicine Gel 0.025 % in the Management of Burning Mouth Syndrome Correlating its Impact on Quality of Life
description ABSTRACT: The aim of this study is to report the results obtained with a protocol of topical application of capsaicin gel 0.025 % in the management of burning mouth syndrome (BMS) to evaluate the influence of the disease and treatment on their quality of life (QOL) using the OHIP-14 questionnaire (Oral Health Impact Profile). After clinical examination and diagnosis of BMS, 10 patients reported the intensity of the burning by means of a subjective score ranging from 0 to 10 and also answered the OHIP-14. Then, a topical application protocol of capsaicin gel 0.025 % was initiated, with weaning from medication and complete withdrawal within 180 days. At each reassessment consultation (30, 60, 90 and 180 days), the patients answered the OHIP-14 and subjective burning scores were collected again. Overall, the capsaicin gel showed gradual reduction or elimination of symptoms of BMS, as well as an improvement in the QOL of patients throughout treatment. At 180 days, after medication withdrawal, 6 patients (60 %) reported total absence of burning and in four patients (40 %) the score remained or decreased. In one patient (10 %) the score increased, although it remained below the initial score. The results showed an improvement in the QOL of all patients who completed the protocol and the impact of BMS on the QOL decreased in relation to the initial score in all patients. The topical use of 0.025 % capsaicin gel was effective in reducing or remitting symptoms of BMS. The OHIP-14 questionnaire showed the negative impact of BMS on patients' QOL and the role of treatment in its improvement.
author Ricken,Carla Militão
Péder,Silvia Natalia Souza de
Kamikawa,Daniela Suemi
Pieralisi,Neli
Chicarelli,Mariliani
Tolentino,Elen de Souza
author_facet Ricken,Carla Militão
Péder,Silvia Natalia Souza de
Kamikawa,Daniela Suemi
Pieralisi,Neli
Chicarelli,Mariliani
Tolentino,Elen de Souza
author_sort Ricken,Carla Militão
title Evaluation of a Protocol For Topical Application of Capsaicine Gel 0.025 % in the Management of Burning Mouth Syndrome Correlating its Impact on Quality of Life
title_short Evaluation of a Protocol For Topical Application of Capsaicine Gel 0.025 % in the Management of Burning Mouth Syndrome Correlating its Impact on Quality of Life
title_full Evaluation of a Protocol For Topical Application of Capsaicine Gel 0.025 % in the Management of Burning Mouth Syndrome Correlating its Impact on Quality of Life
title_fullStr Evaluation of a Protocol For Topical Application of Capsaicine Gel 0.025 % in the Management of Burning Mouth Syndrome Correlating its Impact on Quality of Life
title_full_unstemmed Evaluation of a Protocol For Topical Application of Capsaicine Gel 0.025 % in the Management of Burning Mouth Syndrome Correlating its Impact on Quality of Life
title_sort evaluation of a protocol for topical application of capsaicine gel 0.025 % in the management of burning mouth syndrome correlating its impact on quality of life
publisher Universidad de La Frontera. Facultad de Medicina
publishDate 2021
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-381X2021000200443
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