Chilean benthic species identified as a new source of antibiotic substances

ABSTRACT Benthic marine organisms are a natural source of bioactive substances with applications in medicine to treat infections, cancer and other diseases. In Chile, this community possesses rich biodiversity that has been scarcely studied as a producer of bioactive substance so far. For that reaso...

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Autores principales:	Strahsburger,Erwin, Pizarro,Jessica, Zúñiga,Alex, Ocares,Sergio, Vallejos,Camila, McClelland,Michael
Lenguaje:	English
Publicado:	Pontificia Universidad Católica de Valparaíso. Facultad de Recursos Naturales. Escuela de Ciencias del Mar 2020
Materias:	Staphylococcus aureus antimicrobial organic extract benthos northern Chile
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-560X2020000200257
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spelling	oai:scielo:S0718-560X20200002002572020-05-25Chilean benthic species identified as a new source of antibiotic substancesStrahsburger,ErwinPizarro,JessicaZúñiga,AlexOcares,SergioVallejos,CamilaMcClelland,Michael Staphylococcus aureus antimicrobial organic extract benthos northern Chile ABSTRACT Benthic marine organisms are a natural source of bioactive substances with applications in medicine to treat infections, cancer and other diseases. In Chile, this community possesses rich biodiversity that has been scarcely studied as a producer of bioactive substance so far. For that reason, we studied the potential production of antibiotic substances in 28 benthic species that inhabit the coast of the Tarapacá region in northern Chile, and belong to phylum Porifera, Cnidaria, Mollusca, Sipuncula, Annelida, Echinodermata and Chordata. The antibiotic activity was evaluated on ethanol extract obtained from their entire body or dissected tissues and was tested against Staphylococcus aureus ATCC 25923 with the diffusion agar method. According to the halo diameter, the antibiotic potency was classified as mild, regular or high. In this way, we could identify 21 benthic species as a producer of antibiotic substances with different antibiotic potency. This activity was found in more than one tissue and with regular or high antibiotic activity in the species; Acanthopleura echinata, Chiton cumingsii, Aulacomya atra, Fissurella crassa, Fissurella latimarginata, Luidia magellanica, Stichaster striatus, Arbacia spatuligera, and Loxechinus albus. The extracts obtained from the entire body and showed regular and high antibiotic activity were from the species; Phymanthea pluvia, Abarenicola affinis, Glycera americana, and Ophiactis kroyeri. In conclusion, northern Chile possesses a rich biodiversity of benthic species producer of antibiotic substances, and more research is encouraged to identify these substances with application in medicine.info:eu-repo/semantics/openAccessPontificia Universidad Católica de Valparaíso. Facultad de Recursos Naturales. Escuela de Ciencias del MarLatin american journal of aquatic research v.48 n.2 20202020-05-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-560X2020000200257en10.3856/vol48-issue2-fulltext-2421
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Staphylococcus aureus antimicrobial organic extract benthos northern Chile
spellingShingle	Staphylococcus aureus antimicrobial organic extract benthos northern Chile Strahsburger,Erwin Pizarro,Jessica Zúñiga,Alex Ocares,Sergio Vallejos,Camila McClelland,Michael Chilean benthic species identified as a new source of antibiotic substances
description	ABSTRACT Benthic marine organisms are a natural source of bioactive substances with applications in medicine to treat infections, cancer and other diseases. In Chile, this community possesses rich biodiversity that has been scarcely studied as a producer of bioactive substance so far. For that reason, we studied the potential production of antibiotic substances in 28 benthic species that inhabit the coast of the Tarapacá region in northern Chile, and belong to phylum Porifera, Cnidaria, Mollusca, Sipuncula, Annelida, Echinodermata and Chordata. The antibiotic activity was evaluated on ethanol extract obtained from their entire body or dissected tissues and was tested against Staphylococcus aureus ATCC 25923 with the diffusion agar method. According to the halo diameter, the antibiotic potency was classified as mild, regular or high. In this way, we could identify 21 benthic species as a producer of antibiotic substances with different antibiotic potency. This activity was found in more than one tissue and with regular or high antibiotic activity in the species; Acanthopleura echinata, Chiton cumingsii, Aulacomya atra, Fissurella crassa, Fissurella latimarginata, Luidia magellanica, Stichaster striatus, Arbacia spatuligera, and Loxechinus albus. The extracts obtained from the entire body and showed regular and high antibiotic activity were from the species; Phymanthea pluvia, Abarenicola affinis, Glycera americana, and Ophiactis kroyeri. In conclusion, northern Chile possesses a rich biodiversity of benthic species producer of antibiotic substances, and more research is encouraged to identify these substances with application in medicine.
author	Strahsburger,Erwin Pizarro,Jessica Zúñiga,Alex Ocares,Sergio Vallejos,Camila McClelland,Michael
author_facet	Strahsburger,Erwin Pizarro,Jessica Zúñiga,Alex Ocares,Sergio Vallejos,Camila McClelland,Michael
author_sort	Strahsburger,Erwin
title	Chilean benthic species identified as a new source of antibiotic substances
title_short	Chilean benthic species identified as a new source of antibiotic substances
title_full	Chilean benthic species identified as a new source of antibiotic substances
title_fullStr	Chilean benthic species identified as a new source of antibiotic substances
title_full_unstemmed	Chilean benthic species identified as a new source of antibiotic substances
title_sort	chilean benthic species identified as a new source of antibiotic substances
publisher	Pontificia Universidad Católica de Valparaíso. Facultad de Recursos Naturales. Escuela de Ciencias del Mar
publishDate	2020
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-560X2020000200257
work_keys_str_mv	AT strahsburgererwin chileanbenthicspeciesidentifiedasanewsourceofantibioticsubstances AT pizarrojessica chileanbenthicspeciesidentifiedasanewsourceofantibioticsubstances AT zunigaalex chileanbenthicspeciesidentifiedasanewsourceofantibioticsubstances AT ocaressergio chileanbenthicspeciesidentifiedasanewsourceofantibioticsubstances AT vallejoscamila chileanbenthicspeciesidentifiedasanewsourceofantibioticsubstances AT mcclellandmichael chileanbenthicspeciesidentifiedasanewsourceofantibioticsubstances
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Chilean benthic species identified as a new source of antibiotic substances

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